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  4. 2017, Volume 30, Number 3
Editorial

Artificial Intelligence and Machine Learning in Cardiology – A Change of Paradigm

Claudio Tinoco Mesquita

We are experiencing a change paradigm in modern life. With the presence of computers and intelligent machines everywhere, the predictions of science-fiction books from years ago gradually become reality; these are the times of pervasive computing. Among the computational most frequently mentioned tools in clinical studies and seen with enthusiasm by the scientific community is the Artificial Intelligence and consequently the machines that learn, which is best quoted in its original English form, Machine Learning. In general Artificial Intelligence is defined as the constellation of items (algorithms, robotics, neural networks) that allow a software to have intelligence properties that are comparable to those of a human being, among them learning from databases with minimal human interference.

Obermeyer and Emanuel recently wrote an editorial stating that Machine Learning has become widespread and imperative for solving complex problems in the various fields of science, and in the medical field its use will transform the practice. The use of artificial intelligence is evolving increasingly in cardiology and there are already excellent examples in several areas. Using a sophisticated learning system to electrocardiographic interpretation, Li et al. achieved that electrocardiographic patterns were automatically recognized with an accuracy of 88% for the classification of abnormal rhythms(). One of the most important limitations of the system studied was the quality of the electrocardiographic signal for interpretation and learning, which highlights one of the essential characteristics of Machine Learning, that is the need for accurate and reproducible information for the formation of databases., As databases are usually produced from patients selected for their basic condition, one of the most important points for development is the creation of broader and generalizable databases that do not induce biases in the interpretation of findings, point in which industry is heavily investing at the moment.

[…]

  • Artificial Intelligence/trends
  • Cardiovascular Diseases
  • Computer Systems/trends
  • Echocardiography/trends
  • Machine Learning/trends
  • NucleAR Medicine/trends
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01/01/2017 DOI: 10.5935/2359-4802.20170027 Views 2
Review flowchart
Review Article

Effects of Hypoxia on Heart Rate Variability in Healthy Individuals: A Systematic Review

André Luiz Musmanno Branco Oliveira et al. Philippe de Azeredo Rohan Thiago Rodrigues Gonçalves Pedro Paulo da Silva Soares

Abstract

Background:

Hypoxia is a physiological condition that may affect the cardiac autonomic modulation, which can be assessed by spontaneous fluctuations in heart rate, know as heart rate variability (HRV). Studies have reported reductions or maintenance of HRV in hypoxic situation presenting controversial effects. There is a knowledge gap in relation to changes in HRV during hypoxia.

Objective:

The aim of this study was to systematically review the effects of hypoxia on HRV in unacclimatized healthy adults at rest.

Methods:

This systematic review was performed according to PRISMA guidelines. Search terms used in MEDLINE, SCOPUS, LILACS and EUROPE PMC database were: “heart rate variability” OR “cardiac autonomic modulation” OR “cardiac autonomic regulation” AND NOT intermittent NOT sleep (hypoxia OR altitude). Records were filtered by species, age group and language. Results: At the end of the screening and eligibility, 13 manuscripts remained for qualitative synthesis.

Discussion:

The studies used different experimental protocols involving difference in barometric pressure, oxygen level, time of exposure to hypoxia and control of respiratory rate. Possibly the influence of these factors and also the interindividual variation to hypoxia may justify different responses in HRV.

Conclusion:

Based on the investigated studies, hypoxia has been capable of generating a decrease in HRV, either by reduction or maintenance of vagal modulation, or by sympathetic predominance or even the combination of these responses in healthy adults unacclimatized to hypoxia. This effect appears to be dependent on altitude level and barometric pressure. (Int J Cardiovasc Sci. 2017;30(3):251-261)

  • Altitude
  • Atmospheric Pressure
  • Autonomic Nervous System
  • Heart Rate
  • Hipóxia
  • Review
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01/01/2017 DOI: 10.5935/2359-4802.20170035 Views 1
Review Article

Methods of Endothelial Function Assessment: Description and Applications

Amanda Sampaio Storch et al. João Dario de Mattos Renata Alves Iuri dos Santos Galdino Helena Naly Miguens Rocha

Introduction

The endothelium is a monolayer of cells, called endothelial cells, that lines the interior of blood vessels, including arteries, veins and cardiac chambers, acting as a protective layer between circulating blood and other tissues. The endothelium is crucial for the control of vascular homeostasis, and is involved in the regulation of intracellular signaling, vascular tonus and permeability, coagulation cascade and angiogenesis, among others. One of the main activities of the endothelium is the release of autocrine and paracrine substances in response to stimuli. Injuries to the endothelium trigger an inflammatory response with participation of several cell types – lymphocytes, monocytes, platelets and smooth muscle cells – culminating in endothelial cell dysfunction, stiffness of vessel wall and atherosclerotic plaque formation.

Endothelial dysfunction is an early, key characteristic of development and progression of atherosclerotic plaque and subsequent complications. This is characterized by a reduced bioavailability of endothelium-derived vasodilators, such as nitric oxide (NO), along with a relative or absolute increase in available vasoconstrictors. Such unbalanced condition impairs the endothelium-dependent vasodilation, a functional marker of endothelial dysfunction.

[…]

  • Atherosclerosis
  • Endothelium, Vascular
  • Function, Endothelim
  • Vasodilatation
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01/01/2017 DOI: 10.5935/2359-4802.20170034 Views 3
Original Article

Association between Erectile Dysfunction and Quality of Life in Patients with Coronary Artery Disease

André Tabosa et al. Dinaldo Cavalcanti de Oliveira Vitor H. Stangler Henrique Araújo … Vitor Nunes Maria Isabel Gadelha Danielle A. G. C. Oliveira Emmanuelle Tenório

Abstract

Background:

Erectile dysfunction (ED) and coronary artery disease (CAD) share the same risk factors and the associations between ED, quality of life (QoL) and CAD have been the subject of recent studies.

Objective:

To evaluate whether ED is associated with worsening QoL in patients with CAD.

Methods:

A cross-sectional, multicenter, prospective and analytic study was carried out from EDcember 2014 to April 2016, which recruited 304 men (mean age: 57 ± 9.9 years) with clinical diagnosis of CAD. QoL was assessed using Short Form-36 and ED by the International Erectile Function InEDx. EDscriptive and analytical statistical analyzes were performed, and the Kruskal-Wallis non-parametric test was used to test whether there are significant differences in each quality of life domain when comparing different types of ED. For all tests, p ≤ 0.05 was consiEDred significant.

Results:

The prevalence of ED was 76.3%. The median and percentiles 25 and 75 of each life quality domain according to the absence of ED; mild ED, mild to moderate, moderate and severe ED and severe ED, respectively, were: Functional capacity: 85 (63-100), 75 (50 -95), 60 (32-85), 55 (35-75), 50 (30-70), p < 0.001; Physical aspects: 87 (0-100), 40 (0-100), 0 (0-100), 0 (0-31), 0 (0-12), p < 0.001; Pain: 72 (51-100), 66 (51-100), 74 (51-100), 62 (51-100), 51 (31-62), p = 0.001; General state of health: 77 (62-87), 72 (57-77), 67 (55-82), 67 (59-75), 52 (37-68), p < 0.001; Vitality: 75 (60-85), 65 (50-75), 65 (55-75), 60 (43-75), 50 (32-65), p < 0.001; Social Aspects: 87 (62-100), 87 (62-100), 87 (68-100), 75 (62-100), 75 (50-93), p = 0.139; Emotional Aspects: 100 (58-100), 100 (33-100), 100 (33-100), 100 (0-100), 0 (0-100), p = 0.001; Mental health: 80 (67-89), 72 (60-84), 72 (66-80), 68 (58-80), 56 (50-74), p < 0.001.

Conclusions:

The prevalence of erectile dysfunction was high. ED was associated with worsening of QoL in patients with CAD.

  • Coronary Artery Disease
  • erectile dysfunction
  • Life Style
  • Risk Factors
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01/01/2017 DOI: 10.5935/2359-4802.20170042 Views 1
Figure 1
Original Article

Assessment of Bioactive Compounds, Physicochemical Composition, and In Vitro Antioxidant Activity of Eggplant Flour

Mauara Scorsatto et al. Aline de Castro Pimentel Antonio Jorge Ribeiro da Silva Kebba Sabally … Glorimar Rosa Gláucia Maria Moraes de Oliveira

Abstract

Background:

The eggplant (Solanum melongena) is a fruit of world consumption. Its processing in the form of flour is a way to avoid losses and to take advantage of its nutritional characteristics.

Objective:

This study assessed the physicochemical composition (moisture, proteins, lipids, crude fiber, carbohydrates, minerals, niacin, saponins, titratable acidity, dietary fiber, and total phenols) of eggplant flour prepared from the whole fruit dehydrated in an oven.

Methods:

In vitro antioxidant activity was assessed using the following methods: 2.2-diphenyl-1-picrylhydrazyl radical (DPPH); Ferric Reducing/Antioxidant Power (FRAP); and analysis of polyphenols using HPLC (chlorogenic acid, caffeic acid, ferulic acid, and rutin).

Results:

It was possible to observe: 23.09% carbohydrates; 13.34% proteins; 1.85% lipids; 39.19% total fibers; 1,540 mg/100 g total soluble phenolic compounds; 840 mg/100 g saponins; minerals (potassium, magnesium, copper, iron, zinc, manganese); and niacin. In vitro antioxidant activity was observed through DPPH (455.6 mg ascorbic acid/100 g) and FRAP (486.8 mg ascorbic acid/100 g). The HPLC method determined the presence of ascorbic acid, tyrosine, and phenolic acids (chlorogenic acid, caffeic acid, and ferulic acid).

Conclusion:

The eggplant flour had great fiber content in addition to good content of phenolic compounds and saponins with important antioxidant capacity observed through in vitro assays. As a result, eggplant flour is a good addition to the diet of the population, since it can bring potential health benefits.

  • Antioxidants
  • Diet
  • Hyperlipidemias
  • Nutrition
  • Phenolic Compounds
  • Solanum Melongena
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01/01/2017 DOI: 10.5935/2359-4802.20170046 Views 2
Original Article

Evaluation of Endothelial Function in Pre-Menopausal Women with Coronary Arterial Disease

Wilma Karlla dos Santos Farias et al. Tania Pavão Oliveira Rocha Jorgileia Braga de Melo Erika Joseth Nogueira da Cruz Fonseca … Darci Ramos Fernandes Leticia Prince Pontes Maria Valneide Gomes Andrade José Albuquerque de Figueiredo Neto

Abstract

Background:

The endothelium plays an important vascular regulatory function. Its dysfunction is an early marker of cardiovascular risk. However, there are few studies in our community that assess endothelial function in pre-menopausal women.

Objective:

To assess endothelial function in pre-menopausal women in the presence or absence of coronary artery disease, using a biophysical method (carotid intima media thickness) and a biochemical method (serum levels of hsCRP).

Methods:

Cross-sectional study that evaluated carotid intima-media thickness and serum levels of hsCRP of 31 pre-menopausal women undergoing coronary angiography at the Hemodynamics Service of Hospital Universitário da Universidade Federal do Maranhão from March 2012 to July 2013. The data were sent to statistical analysis and a statistical significance level of 5% was considered.

Results:

The sample was divided into two groups according to the presence of coronary artery disease (CAD): CAD group (n = 13) and group without CAD (n = 18). The average ages for the groups were 57.92 ± 5.17 and 51.72 ± 4.63 years, respectively (p = 0.001). CIMT was abnormal in 29.03% in the general population. Carotid intima-media thickness was 1.55 ± 0.78 mm in the general group, 1.92 ± 0.94 mm in the CAD group and 1.18 ± 0.71 mm in the group without CAD (p = 0.001). CAD patients had predominance of abnormal CMIT compared those without CAD: 36.46% vs. 22.22%, respectively. There was a sensitivity of 38%, specificity of 77% with a positive predictive value of 0.55 and a negative predictive value of 0.63 with likelihood ratio of 1.73. Patients with abnormal CIMT presented higher levels of hsCRP, but without statistical significance. CAD patients had higher levels of hsCRP, but without statistical significance.

Conclusion:

In the population studied, assessment of endothelial function using the CIMT method showed higher sensitivity and specificity for the diagnosis of CAD compared to the measurement of hsCRP levels in menopausal women.

  • Atherosclerosis
  • Cineangiography
  • Coronary Artery Disease
  • Endothelium / dysfunction
  • Premenopause
  • Women
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01/01/2017 DOI: 10.5935/2359-4802.20170043 Views 1
Original Article

High Blood Pressure in Pre-Adolescents and Adolescents in Petrópolis: Prevalence and Correlation with Overweight and Obesity

Flavio Figueirinha et al. Gesmar Volga Haddad Herdy

Abstract

Background:

Arterial hypertension is a multisystem disease that increases the risk of fatal cardiac events.

Objectives:

This study aims to determine the prevalence of increased blood pressure levels of pre-adolescents and adolescents and correlate these pressure levels with the presence of overweight or obesity and family history of hypertension.

Methods:

In an observational, cross-sectional study, a sample of 157 students from the city of Petropolis aged from ten to nineteen was randomly selected. The study included four public schools and one private school. The persons responsible for each student answered a questionnaire on pre-existing conditions, family history of hypertension and previous blood pressure measurements. A thorough physical examination, anthropometric evaluation and two blood pressure readings were taken at intervals of at least ten minutes, on three different occasions, totaling six measurements.

Results:

Blood pressure levels have shown to be abnormal in 17 (10.8% / IC95% 5.9-15.7) studied individuals. Statistical significance was found between the change in blood pressure and the presence of overweight and obesity (p < 0.001), as well as with the presence of family history of hypertension (p < 0.05). A portion of 32.5% of the subjects had never had their blood pressure measured, and over the twelve months prior to the study, 45.5% of the sample had not measured it either.

Conclusions:

This study demonstrated that a significant percentage of students in the city of Petrópolis, in the state of Rio de Janeiro, has high blood pressure with a statistically significant correlation with overweight or obesity and a family history of hypertension.

  • Adolescent
  • Child
  • Hypertension/epidemiology
  • Obesity
  • Oveweight
  • Prevalence
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01/01/2017 DOI: 10.5935/2359-4802.20170040 Views 1
Figure 1
Original Article

Profile of Patients Hospitalized for Heart Failure in Tertiary Care Hospital

Milton Ricardo Poffo et al. Amberson Vieira de Assis Maíra Fracasso Ozir Miguel Londero Filho … Sulyane Matos de Menezes Alves Ana Paula Bald Camila Bussolo Schmitt Nilton Rogério Alves Filho

Abstract

Background:

Heart failure is a highly prevalent disease, responsible for many admissions and high mortality rates in our country. The treatment influences patient’s mortality and quality of life.

Objective:

To identify and compare the clinical and epidemiological survivor’s and non-survivor’s profiles and treatment of patients hospitalized with heart failure with the international literature.

Methods:

Cross-sectional, retrospective study of 816 survivors and non-survivors with heart failure. All patients had their clinical and epidemiological, laboratory and echocardiographic data and treatment recorded.

Results:

Most patients were in functional class III/IV. Mean age was 66.5 ± 13.8 years. Half of the patients were men and 88.3% were Caucasians. In-hospital mortality was 11,2%. Highly mortality was associated with old age, Caucasian ethnicity, high functional class, readmissions, prolonged hospitalization, presence of coronary artery disease, chronic atrial fibrillation, severe mitral regurgitation, restrictive diastolic dysfunction, renal dysfunction, and elevated natriuretic peptide levels, as well as with patients who had pulmonary embolism, acute coronary syndrome, pulmonary infection or required dialysis during hospitalization. The use of angiotensin-converting enzyme inhibitors or angiotensin-receptor blockers at admission was significantly higher among survivors.

Conclusion:

In-hospital mortality was high when compared to international averages, but it was similar to other Brazilian referral services. Numerous higher severity indicators were observed in the non-survivor group.

  • Heart Failure / mortality
  • Hospitalization
  • Prevalence
  • Restrospective Studies
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01/01/2017 DOI: 10.5935/2359-4802.20170044 Views 1
Figure 1
Case Report

Case Report: Catheter-Related Interatrial Septum Endocarditis Caused by Candida Parapsilosis

Gustavo Neves de Araújo et al. Felipe H. Valle Douglas M. Freitas Felipe Martins Lampa … Miguel Gus Luis E. Rohde

Introduction

Patients with end-stage chronic kidney disease without mature arteriovenous fistula frequently require central venous access for dialytic therapy. More than 15 percent of patients who receive these catheters have complications such as infection, arterial puncture, thrombosis and pneumothorax. Infective endocarditis (IE) is a rare and serious complication with high morbidity and mortality. Right-sided endocarditis is uncommon due to low hemodynamic pressure, but patients using central venous catheters have an increased risk. The correct therapeutic approach whenever there is no valvar involvement is not well defined. We report a case of interatrial septum endocarditis caused by candida sp., associated to the prolonged use of catheter.

[…]

  • Candida
  • Catheter-Related Infections
  • Endocarditis, bacterial
  • Renal Insufficiency, Chronic
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01/01/2017 DOI: 10.5935/2359-4802.20170030 Views 2
Figure 1
Case Report

Takotsubo Cardiomyopathy with Extracorporeal Membrane Oxygenation (ECMO) Requirement after Atrial Myxoma Surgery

Fernando Garagoli et al. Aníbal Arias Vadim Kotowicz Arturo Cagide César Belziti

Introduction

Takotsubo’s syndrome is a cardiomyopathy characterized by transient left ventricular dysfunction. This condition is often described in postmenopausal women secondary to physical or emotional triggers. The clinical behavior mimics an acute coronary syndrome. However, angiography shows no obstructive epicardial coronary artery disease.

This syndrome is considered a reversible cardiomyopathy. However, patients with Takotsubo cardiomyopathy have risk of serious complications, such as cardiogenic shock, ventricular tachycardia and ventricular thrombus.

[…]

  • Extracorporeal Membrane Oxygenation
  • Takotsubo Cardiomyopathy/complications
  • Takotsubo Cardiomyopathy/surgery
  • Ventricular Dysfunction, Left
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01/01/2017 DOI: 10.5935/2359-4802.20170022 Views 2
Figure 1
Original Article

Gallic Acid and Cyclosporine Mixture and their Effects on Cardiac Dysfunction Induced by Ischemia/Reperfusion and eNOS/iNOS Expression

Mohammad Badavi et al. Najmeh Sadeghi Mahin Dianat Alireza Samarbafzadeh

Abstract

Background:

Although many researches have been conducted on either a certain antioxidant or mPTP individually, little attention has been drawn to the effects of co-administration of an antioxidant and mPTP inhibitor together on cardiac dysfunction after I/R injury.

Objectives:

This study aims at determining the effects of gallic acid (as Antioxidant) combined with cyclosporine A (CsA) (as mPTP inhibitor) on I/R induced cardiac and endothelial (role of NO) dysfunction.

Methods:

Male Wistar rats were pretreated with gallic acid (7.5, 15, or 30 mg.kg-1 body weight, daily) for a period of 10 days. Then, the heart was isolated and exposed to 30-minute ischemia and perfused by CsA (0.2 µM) 20 min during reperfusion period.

Results:

The data have shown that infarct size was decreased significantly by CsA and gallic acid alone (p < 0.05, one way ANOVA followed by LSD test), however the combination of both drugs had more significant improving effects (p < 0.001). The combination of these two drugs improved more significantly maximum rate of rise and fall of ventricular pressure (±dp.dt-1 max), rate pressure product (RPP), left ventricular developed pressure (LVDP), heart rate and coronary flow rather than applying each one alone (p < 0.05, repeated measurement ANOVA followed by LSD test).

Conclusions:

In conclusion, benefiting from an antioxidant concomitant with an mPTP inhibitor could have more improving effects on the cardiac dysfunction induced by I/R injury.

  • Antioxidants
  • cyclosporine
  • Endothelium
  • Gallic Acid
  • nitric oxide Synthase
  • Rats
  • Reperfusion
  • Ventricular Function
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01/01/2017 DOI: 10.5935/2359-4802.20170047 Views 1
Original Article

Matricial Support and Arterial Hypertension Control

Clóvis Hoepfner et al. Morgana Longo Andressa de Oliveira Coiradas Laíssa Mara Rodrigues Teixeira

Abstract

Background:

A continuing education program for health professionals improves their performance and increases hypertension control rates.

Objective:

To estimate the prevalence of hypertension control and therapeutic inertia among adults treated at Primary Health Care Units after a continuing education program focused on cardiology for health professionals.

Methods:

A cross-sectional study was carried out, which included cluster sampling and analysis of medical records. We evaluated 463 patients with high blood pressure and analyzed the blood pressure, medications, and therapeutic increments in 2013, which were compared to the data obtained in 2007.

Results:

There was prevalence of female patients and appointments at the Family Health Care Units. The age ranged between 24 and 92 years (mean of 61.7 years). There was a reduction in the mean blood pressure (148.62/91.60 ± 23.52/14.51 mmHg to 137.60/84.03 ± 21.84/12.72) between the first and last records, and BP control in 58% of the sample, that is, higher than the 36.6% found in 2007. In the analyzed period, there was a therapeutic increment of 39% in appointments, which benefited 52% patients with high blood pressure, higher than the 12% and 29.5%, respectively, found in 2007. The mean number of drugs per patient increased from 1.85 to 2.05, with a predominance of diuretics and angiotensin-converting-enzyme inhibitors.

Conclusion:

There was a reduction in the clinical inertia and increased control of arterial hypertension was observed, compared with the findings of the previous study. The result suggests that the matricial support program for health professionals and other measures to improve disease control in the Primary Health Care Units were effective.

  • health centers
  • Health Education
  • Hypertension / prevention & control
  • Hypertension/epidemiology
  • Inertia
  • Prevalence
  • Primary Health Care
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01/01/2017 DOI: 10.5935/2359-4802.20170045 Views 2

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Mesquita CT. Artificial Intelligence and Machine Learning in Cardiology – A Change of Paradigm. International Journal of Cardiovascular Sciences 2017;30(3):187-8.

Electronic Document Format (ABNT)

Mesquita, Claudio Tinoco. Artificial Intelligence and Machine Learning in Cardiology – A Change of Paradigm. International Journal of Cardiovascular Sciences, v. 30, n. 3, p. 187-188, Dec. 2016.

Electronic Document Format (APA)

Mesquita, C. T. (2017). Artificial Intelligence and Machine Learning in Cardiology – A Change of Paradigm. International Journal of Cardiovascular Sciences, 30(3), 187-188.

Electronic Document Format (ISO)

Mesquita, Claudio Tinoco. Artificial Intelligence and Machine Learning in Cardiology – A Change of Paradigm. International Journal of Cardiovascular Sciences [online]. 2017, vol. 30, n. 3, [cited 2026-10-14], pp. 187-188. Available from: <https://journals.cardiol.br/en/article/artificial-intelligence-and-machine-learning-in-cardiology-a-change-of-paradigm/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Oliveira ALMB, Rohan PA, Gonçalves TR, Soares PPS. Effects of Hypoxia on Heart Rate Variability in Healthy Individuals: A Systematic Review. International Journal of Cardiovascular Sciences 2017;30(3):251-6.

Electronic Document Format (ABNT)

Oliveira, André Luiz Musmanno Branco; Rohan, Philippe de Azeredo; Gonçalves, Thiago Rodrigues; Soares, Pedro Paulo da Silva. Effects of Hypoxia on Heart Rate Variability in Healthy Individuals: A Systematic Review. International Journal of Cardiovascular Sciences, v. 30, n. 3, p. 251-261, Dec. 2016.

Electronic Document Format (APA)

Oliveira, A. L. M. B., Rohan, P. A., Gonçalves, T. R., & Soares, P. P. S. (2017). Effects of Hypoxia on Heart Rate Variability in Healthy Individuals: A Systematic Review. International Journal of Cardiovascular Sciences, 30(3), 251-261.

Electronic Document Format (ISO)

Oliveira, André Luiz Musmanno Branco and Rohan, Philippe de Azeredo and Gonçalves, Thiago Rodrigues and Soares, Pedro Paulo da Silva. Effects of Hypoxia on Heart Rate Variability in Healthy Individuals: A Systematic Review. International Journal of Cardiovascular Sciences [online]. 2017, vol. 30, n. 3, [cited 2026-10-14], pp. 251-261. Available from: <https://journals.cardiol.br/en/article/effects-of-hypoxia-on-heart-rate-variability-in-healthy-individuals-a-systematic-review/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Storch AS, Mattos JD, Alves R, Galdino IS, Rocha HNM. Methods of Endothelial Function Assessment: Description and Applications. International Journal of Cardiovascular Sciences 2017;30(3):262-73.

Electronic Document Format (ABNT)

Storch, Amanda Sampaio; Mattos, João Dario de; Alves, Renata; Galdino, Iuri dos Santos; Rocha, Helena Naly Miguens. Methods of Endothelial Function Assessment: Description and Applications. International Journal of Cardiovascular Sciences, v. 30, n. 3, p. 262-273, Dec. 2016.

Electronic Document Format (APA)

Storch, A. S., Mattos, J. D. , Alves, R., Galdino, I. S., & Rocha, H. N. M. (2017). Methods of Endothelial Function Assessment: Description and Applications. International Journal of Cardiovascular Sciences, 30(3), 262-273.

Electronic Document Format (ISO)

Storch, Amanda Sampaio and Mattos, João Dario de and Alves, Renata and Galdino, Iuri dos Santos and Rocha, Helena Naly Miguens. Methods of Endothelial Function Assessment: Description and Applications. International Journal of Cardiovascular Sciences [online]. 2017, vol. 30, n. 3, [cited 2026-10-14], pp. 262-273. Available from: <https://journals.cardiol.br/en/article/methods-of-endothelial-function-assessment-description-and-applications/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Tabosa A, Oliveira DC, Stangler VH, Araújo H, Nunes V, Gadelha MI, Oliveira DAGC, et al. Association between Erectile Dysfunction and Quality of Life in Patients with Coronary Artery Disease. International Journal of Cardiovascular Sciences 2017;30(3):219-26.

Electronic Document Format (ABNT)

Tabosa, André; Oliveira, Dinaldo Cavalcanti de; Stangler, Vitor H.; Araújo, Henrique; Nunes, Vitor; Gadelha, Maria Isabel; Oliveira, Danielle A. G. C.; Tenório, Emmanuelle. Association between Erectile Dysfunction and Quality of Life in Patients with Coronary Artery Disease. International Journal of Cardiovascular Sciences, v. 30, n. 3, p. 219-226, Dec. 2016.

Electronic Document Format (APA)

Tabosa, A., Oliveira, D. C. , Stangler, V. H., Araújo, H., Nunes, V., Gadelha, M. I., Oliveira, D. A. G. C., & Tenório, E. (2017). Association between Erectile Dysfunction and Quality of Life in Patients with Coronary Artery Disease. International Journal of Cardiovascular Sciences, 30(3), 219-226.

Electronic Document Format (ISO)

Tabosa, André and Oliveira, Dinaldo Cavalcanti de and Stangler, Vitor H. and Araújo, Henrique and Nunes, Vitor and Gadelha, Maria Isabel and Oliveira, Danielle A. G. C. and Tenório, Emmanuelle. Association between Erectile Dysfunction and Quality of Life in Patients with Coronary Artery Disease. International Journal of Cardiovascular Sciences [online]. 2017, vol. 30, n. 3, [cited 2026-10-14], pp. 219-226. Available from: <https://journals.cardiol.br/en/article/association-between-erectile-dysfunction-and-quality-of-life-in-patients-with-coronary-artery-disease/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Scorsatto M, Pimentel AC, Silva AJR, Sabally K, Rosa G, Oliveira GMM. Assessment of Bioactive Compounds, Physicochemical Composition, and In Vitro Antioxidant Activity of Eggplant Flour. International Journal of Cardiovascular Sciences 2017;30(3):235-42.

Electronic Document Format (ABNT)

Scorsatto, Mauara; Pimentel, Aline de Castro; Silva, Antonio Jorge Ribeiro da; Sabally, Kebba; Rosa, Glorimar; Oliveira, Gláucia Maria Moraes de. Assessment of Bioactive Compounds, Physicochemical Composition, and In Vitro Antioxidant Activity of Eggplant Flour. International Journal of Cardiovascular Sciences, v. 30, n. 3, p. 235-242, Dec. 2016.

Electronic Document Format (APA)

Scorsatto, M., Pimentel, A. C., Silva, A. J. R. , Sabally, K., Rosa, G., & Oliveira, G. M. M. (2017). Assessment of Bioactive Compounds, Physicochemical Composition, and In Vitro Antioxidant Activity of Eggplant Flour. International Journal of Cardiovascular Sciences, 30(3), 235-242.

Electronic Document Format (ISO)

Scorsatto, Mauara and Pimentel, Aline de Castro and Silva, Antonio Jorge Ribeiro da and Sabally, Kebba and Rosa, Glorimar and Oliveira, Gláucia Maria Moraes de. Assessment of Bioactive Compounds, Physicochemical Composition, and In Vitro Antioxidant Activity of Eggplant Flour. International Journal of Cardiovascular Sciences [online]. 2017, vol. 30, n. 3, [cited 2026-10-14], pp. 235-242. Available from: <https://journals.cardiol.br/en/article/assessment-of-bioactive-compounds-physicochemical-composition-and-in-vitro-antioxidant-activity-of-eggplant-flour/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Farias WKS, Rocha TPO, Melo JB, Fonseca EJNC, Fernandes DR, Pontes LP, Andrade MVG, et al. Evaluation of Endothelial Function in Pre-Menopausal Women with Coronary Arterial Disease. International Journal of Cardiovascular Sciences 2017;30(3):227-34.

Electronic Document Format (ABNT)

Farias, Wilma Karlla dos Santos; Rocha, Tania Pavão Oliveira; Melo, Jorgileia Braga de; Fonseca, Erika Joseth Nogueira da Cruz; Fernandes, Darci Ramos; Pontes, Leticia Prince; Andrade, Maria Valneide Gomes; Figueiredo Neto, José Albuquerque de. Evaluation of Endothelial Function in Pre-Menopausal Women with Coronary Arterial Disease. International Journal of Cardiovascular Sciences, v. 30, n. 3, p. 227-234, Dec. 2016.

Electronic Document Format (APA)

Farias, W. K. S., Rocha, T. P. O., Melo, J. B. , Fonseca, E. J. N. C., Fernandes, D. R., Pontes, L. P., Andrade, M. V. G., & Figueiredo Neto, J. A. (2017). Evaluation of Endothelial Function in Pre-Menopausal Women with Coronary Arterial Disease. International Journal of Cardiovascular Sciences, 30(3), 227-234.

Electronic Document Format (ISO)

Farias, Wilma Karlla dos Santos and Rocha, Tania Pavão Oliveira and Melo, Jorgileia Braga de and Fonseca, Erika Joseth Nogueira da Cruz and Fernandes, Darci Ramos and Pontes, Leticia Prince and Andrade, Maria Valneide Gomes and Figueiredo Neto, José Albuquerque de. Evaluation of Endothelial Function in Pre-Menopausal Women with Coronary Arterial Disease. International Journal of Cardiovascular Sciences [online]. 2017, vol. 30, n. 3, [cited 2026-10-14], pp. 227-234. Available from: <https://journals.cardiol.br/en/article/evaluation-of-endothelial-function-in-pre-menopausal-women-with-coronary-arterial-disease/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Figueirinha F, Herdy GVH. High Blood Pressure in Pre-Adolescents and Adolescents in Petrópolis: Prevalence and Correlation with Overweight and Obesity. International Journal of Cardiovascular Sciences 2017;30(3):243-50.

Electronic Document Format (ABNT)

Figueirinha, Flavio; Herdy, Gesmar Volga Haddad. High Blood Pressure in Pre-Adolescents and Adolescents in Petrópolis: Prevalence and Correlation with Overweight and Obesity. International Journal of Cardiovascular Sciences, v. 30, n. 3, p. 243-250, Dec. 2016.

Electronic Document Format (APA)

Figueirinha, F., & Herdy, G. V. H. (2017). High Blood Pressure in Pre-Adolescents and Adolescents in Petrópolis: Prevalence and Correlation with Overweight and Obesity. International Journal of Cardiovascular Sciences, 30(3), 243-250.

Electronic Document Format (ISO)

Figueirinha, Flavio and Herdy, Gesmar Volga Haddad. High Blood Pressure in Pre-Adolescents and Adolescents in Petrópolis: Prevalence and Correlation with Overweight and Obesity. International Journal of Cardiovascular Sciences [online]. 2017, vol. 30, n. 3, [cited 2026-10-14], pp. 243-250. Available from: <https://journals.cardiol.br/en/article/high-blood-pressure-in-pre-adolescents-and-adolescents-in-petropolis-prevalence-and-correlation-with-overweight-and-obesity/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Poffo MR, Assis AV, Fracasso M, Londero Filho OM, Alves SMM, Bald AP, Schmitt CB, et al. Profile of Patients Hospitalized for Heart Failure in Tertiary Care Hospital. International Journal of Cardiovascular Sciences 2017;30(3):189-98.

Electronic Document Format (ABNT)

Poffo, Milton Ricardo; Assis, Amberson Vieira de; Fracasso, Maíra; Londero Filho, Ozir Miguel; Alves, Sulyane Matos de Menezes; Bald, Ana Paula; Schmitt, Camila Bussolo; Alves Filho, Nilton Rogério. Profile of Patients Hospitalized for Heart Failure in Tertiary Care Hospital. International Journal of Cardiovascular Sciences, v. 30, n. 3, p. 189-198, Dec. 2016.

Electronic Document Format (APA)

Poffo, M. R., Assis, A. V. , Fracasso, M., Londero Filho, O. M., Alves, S. M. M., Bald, A. P., Schmitt, C. B., & Alves Filho, N. R. (2017). Profile of Patients Hospitalized for Heart Failure in Tertiary Care Hospital. International Journal of Cardiovascular Sciences, 30(3), 189-198.

Electronic Document Format (ISO)

Poffo, Milton Ricardo and Assis, Amberson Vieira de and Fracasso, Maíra and Londero Filho, Ozir Miguel and Alves, Sulyane Matos de Menezes and Bald, Ana Paula and Schmitt, Camila Bussolo and Alves Filho, Nilton Rogério. Profile of Patients Hospitalized for Heart Failure in Tertiary Care Hospital. International Journal of Cardiovascular Sciences [online]. 2017, vol. 30, n. 3, [cited 2026-10-14], pp. 189-198. Available from: <https://journals.cardiol.br/en/article/profile-of-patients-hospitalized-for-heart-failure-in-tertiary-care-hospital/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Araújo GN, Valle FH, Freitas DM, Lampa FM, Gus M, Rohde LE. Case Report: Catheter-Related Interatrial Septum Endocarditis Caused by Candida Parapsilosis. International Journal of Cardiovascular Sciences 2017;30(3):274-6.

Electronic Document Format (ABNT)

Araújo, Gustavo Neves de; Valle, Felipe H.; Freitas, Douglas M.; Lampa, Felipe Martins; Gus, Miguel; Rohde, Luis E.. Case Report: Catheter-Related Interatrial Septum Endocarditis Caused by Candida Parapsilosis. International Journal of Cardiovascular Sciences, v. 30, n. 3, p. 274-276, Dec. 2016.

Electronic Document Format (APA)

Araújo, G. N. , Valle, F. H., Freitas, D. M., Lampa, F. M., Gus, M., & Rohde, L. E. (2017). Case Report: Catheter-Related Interatrial Septum Endocarditis Caused by Candida Parapsilosis. International Journal of Cardiovascular Sciences, 30(3), 274-276.

Electronic Document Format (ISO)

Araújo, Gustavo Neves de and Valle, Felipe H. and Freitas, Douglas M. and Lampa, Felipe Martins and Gus, Miguel and Rohde, Luis E.. Case Report: Catheter-Related Interatrial Septum Endocarditis Caused by Candida Parapsilosis. International Journal of Cardiovascular Sciences [online]. 2017, vol. 30, n. 3, [cited 2026-10-14], pp. 274-276. Available from: <https://journals.cardiol.br/en/article/case-report-catheter-related-interatrial-septum-endocarditis-caused-by-candida-parapsilosis/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Garagoli F, Arias A, Kotowicz V, Cagide A, Belziti C. Takotsubo Cardiomyopathy with Extracorporeal Membrane Oxygenation (ECMO) Requirement after Atrial Myxoma Surgery. International Journal of Cardiovascular Sciences 2017;30(3):277-80.

Electronic Document Format (ABNT)

Garagoli, Fernando; Arias, Aníbal; Kotowicz, Vadim; Cagide, Arturo; Belziti, César. Takotsubo Cardiomyopathy with Extracorporeal Membrane Oxygenation (ECMO) Requirement after Atrial Myxoma Surgery. International Journal of Cardiovascular Sciences, v. 30, n. 3, p. 277-280, Dec. 2016.

Electronic Document Format (APA)

Garagoli, F., Arias, A., Kotowicz, V., Cagide, A., & Belziti, C. (2017). Takotsubo Cardiomyopathy with Extracorporeal Membrane Oxygenation (ECMO) Requirement after Atrial Myxoma Surgery. International Journal of Cardiovascular Sciences, 30(3), 277-280.

Electronic Document Format (ISO)

Garagoli, Fernando and Arias, Aníbal and Kotowicz, Vadim and Cagide, Arturo and Belziti, César. Takotsubo Cardiomyopathy with Extracorporeal Membrane Oxygenation (ECMO) Requirement after Atrial Myxoma Surgery. International Journal of Cardiovascular Sciences [online]. 2017, vol. 30, n. 3, [cited 2026-10-14], pp. 277-280. Available from: <https://journals.cardiol.br/en/article/takotsubo-cardiomyopathy-with-extracorporeal-membrane-oxygenation-ecmo-requirement-after-atrial-myxoma-surgery/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Badavi M, Sadeghi N, Dianat M, Samarbafzadeh A. Gallic Acid and Cyclosporine Mixture and their Effects on Cardiac Dysfunction Induced by Ischemia/Reperfusion and eNOS/iNOS Expression. International Journal of Cardiovascular Sciences 2017;30(3):207-18.

Electronic Document Format (ABNT)

Badavi, Mohammad; Sadeghi, Najmeh; Dianat, Mahin; Samarbafzadeh, Alireza. Gallic Acid and Cyclosporine Mixture and their Effects on Cardiac Dysfunction Induced by Ischemia/Reperfusion and eNOS/iNOS Expression. International Journal of Cardiovascular Sciences, v. 30, n. 3, p. 207-218, Dec. 2016.

Electronic Document Format (APA)

Badavi, M., Sadeghi, N., Dianat, M., & Samarbafzadeh, A. (2017). Gallic Acid and Cyclosporine Mixture and their Effects on Cardiac Dysfunction Induced by Ischemia/Reperfusion and eNOS/iNOS Expression. International Journal of Cardiovascular Sciences, 30(3), 207-218.

Electronic Document Format (ISO)

Badavi, Mohammad and Sadeghi, Najmeh and Dianat, Mahin and Samarbafzadeh, Alireza. Gallic Acid and Cyclosporine Mixture and their Effects on Cardiac Dysfunction Induced by Ischemia/Reperfusion and eNOS/iNOS Expression. International Journal of Cardiovascular Sciences [online]. 2017, vol. 30, n. 3, [cited 2026-10-14], pp. 207-218. Available from: <https://journals.cardiol.br/en/article/gallic-acid-and-cyclosporine-mixture-and-their-effects-on-cardiac-dysfunction-induced-by-ischemia-reperfusion-and-enos-inos-expression/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Hoepfner C, Longo M, Coiradas AO, Teixeira LMR. Matricial Support and Arterial Hypertension Control. International Journal of Cardiovascular Sciences 2017;30(3):199-206.

Electronic Document Format (ABNT)

Hoepfner, Clóvis; Longo, Morgana; Coiradas, Andressa de Oliveira; Teixeira, Laíssa Mara Rodrigues. Matricial Support and Arterial Hypertension Control. International Journal of Cardiovascular Sciences, v. 30, n. 3, p. 199-206, Dec. 2016.

Electronic Document Format (APA)

Hoepfner, C., Longo, M., Coiradas, A. O., & Teixeira, L. M. R. (2017). Matricial Support and Arterial Hypertension Control. International Journal of Cardiovascular Sciences, 30(3), 199-206.

Electronic Document Format (ISO)

Hoepfner, Clóvis and Longo, Morgana and Coiradas, Andressa de Oliveira and Teixeira, Laíssa Mara Rodrigues. Matricial Support and Arterial Hypertension Control. International Journal of Cardiovascular Sciences [online]. 2017, vol. 30, n. 3, [cited 2026-10-14], pp. 199-206. Available from: <https://journals.cardiol.br/en/article/matricial-support-and-arterial-hypertension-control/>. ISSN 2359-4802

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