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  4. 2014, Volume 103, Number 5
Figure 1
Anatomopathological Session

Case 5/2014 – 41-Year-Old Woman with Rheumatic Disease and Previous Mitral Valve Repair with Pulmonary Embolism and Cardiogenic and Septic Shock

Eduardo Gomes Lima et al. Ricardo D’Oliveira Vieira Paula Bombonati Jussara Bianchi Castelli

Clinical aspects

This is 41-year-old patient with a history of rheumatic disease who developed mitral stenosis and underwent mitral commissurotomy at age 36 due to the presence of incapacitating symptoms. In our country, the combination of mitral stenosis with rheumatic disease is quite common . About 25% of all patients with rheumatic disease have isolated mitral stenosis; 40% have double mitral dysfunction . The mean time interval between the initial acute onset and the appearance of symptoms can vary from a few to more than 20 years.

The presence of symptoms of heart failure (classes III and IV of the New York Heart Association), together with echocardiographic data that confirm significant anatomic lesion, is crucial for intervention indication: balloon valvuloplasty or surgery (commissurotomy or valve replacement). Whenever possible, there is an attempt to correct the valve defect, keeping the patient’s valve system, postponing prosthesis implantation. In this case, commissurotomy was performed, which maintained the patient well for approximately five years, when she started to present symptoms again, when mitral valve repair was performed. This evolution in the rheumatic patient can occur due to repeated episodes of valvulitis, hence the need to maintain secondary prophylaxis with benzathine penicillin in patients with cardiac involvement, preferably throughout life or up to the fifth decade, when it is not possible .

[…]

  • Acinetobacter Infections
  • Mitral Valve Stenosis / serugery
  • Pulmonary embolism
  • Shock, Cardiogenic
  • Shock, Septic
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01/11/2014 DOI: 10.5935/abc.20140180 Views 1
Figure 1
Editorial

Cardiovascular Computed Tomography and Magnetic Resonance: History and Growing Impact in Brazil and in the World

Marcelo Souto Nacif et al. Carlos Eduardo Rochitte

Growth in Brazil and in the World

Cardiovascular computed tomography and magnetic resonance are an important topic within the area of cardiovascular imaging in Brazil and in the world. In the Arquivos Brasileiros de Cardiologia this is not different, and despite the increased focus in clinical study, these two topics have grown in impact and scientific publications in recent years.

It is notorious the expansion of the national technological park with entrance of countless devices capable of performing advanced studies using cardiovascular tomography and magnetic resonance with increasing impetus for opening more centers specialized in these methods.

[…]

  • Diagnostic Imaging/history
  • Diagnostic Imaging/trends
  • Magnetic Resonance Spectroscopy/history
  • Tomography, X-Ray Computed/history
  • Tomography,X-Ray Computed/trends
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01/11/2014 DOI: 10.5935/abc.20140186 Views 2
Erratum

Edition of March 2014, vol. 102 (3), Supl. 1, pg. 1-61

The “Brazilian Society of Cardiology Guidelines on Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction (2nd Edition, 2007) – 2013 Updating”, published as supplement number 3 of the March 2014 edition of the Arquivos Brasileiros de Cardiologia [Arq Bras Cardiol. 2014;102(3Supl.1):1-61], has undergone the following corrections:

On page 46, item “Lipid Approach – Summary of Recommendations and Evidence”, sub-item “Class 1 recommendations”, the following text has been considered second topic:

[…]

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01/11/2014 DOI: 10.5935/abc.2014S001e
Letter to the Editor

ACE I/D Gene Polymorphism in Children with Family History of Premature Coronary Disease

Dilek Yý lmaz Çiftdoð an

Additional information:

In addition to ACE I/D gene polymorphism, glycoprotein IIIa, factor V G1691A, factor V H1299R, prothrombin G20210A and apolipoprotein E polymorphism had been investigated in the same study group. These results were published in various journals.

* Ciftdoğan DY. Glycoprotein IIIa gene polymorphism in children with a family history of premature coronary artery disease. Acta Cardiol. 2010 Dec;65(6):695; author reply 695-6.

[…]

  • Child
  • Coronary Artery Disease
  • Peptidyl-Dipeptidase A
  • Polymorfism, Genetic
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01/11/2014 DOI: 10.5935/abc.20140182 Views 1
Figure 1
Case Report

Multiple Benefits of Rehabilitation in a Patient with Heart and Renal Failure

Carlos Alberto Cordeiro Hossri et al. Fernando José Pinho Queiroga Júnior Vitor Oliveira Carvalho Carlos Roberto Ribeiro Carvalho Andre Luis Pereira Albuquerque

Introduction

Heart failure is associated with high mortality and significantly reduced exercise capacity in many cases, despite medical treatment. Patients may present also renal failure, one of the most important comorbidities, which contributes even more to a poor prognosis, especially in patients who are already attending dialysis sessions . Reduction of renal function occurs in approximately 25% of patients with chronic heart failure, regardless the severity of left ventricular dysfunction .

Exercise training is formally recommended as a safe non-pharmacological intervention in stable heart failure ,. Nevertheless, many patients in severe stage are extremely symptomatic and consider themselves as incapable to attend an exerce training program. The association of heart failure and renal failure in use of continuous ambulatory peritoneal dialysis makes this attendance even more complicated. The physicians also are insecure and resistant to recommend cardiopulmonary rehabilitation for a patient with such important impairment.

[…]

  • Exercise
  • Exercise Therapy
  • Heart failure / rehabilitation
  • Renal Insufficiency / rehabilitation
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01/11/2014 DOI: 10.5935/abc.20140127 Views 1
Left Internal Mammary Artery Graft-to-Pulmonary Artery Fistula
Image

Left Internal Mammary Artery Graft-to-Pulmonary Artery Fistula

Emmanouil Petrou et al. Ioannis Iakovou

A

n

[…]

  • Arteriovenous Fistula
  • Mammary Arteries
  • Myocardial Revascularization
  • Pulmonary Artery
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01/11/2014 DOI: 10.5935/abc.20140160
Figure 1
Original Article

Impact of Intensive Physiotherapy on Cognitive Function after Coronary Artery Bypass Graft Surgery

Elder dos Santos Cavalcante et al. Rosmeiri Magario César Augusto Conforti Gerson Cipriano Júnior … Ross Arena Antonio Carlos C. Carvalho Enio Buffolo Bráulio Luna Filho

Background:

Coronary artery bypass graft (CABG) is a standard surgical option for patients with diffuse and significant arterial plaque. This procedure, however, is not free of postoperative complications, especially pulmonary and cognitive disorders.

Objective:

This study aimed at comparing the impact of two different physiotherapy treatment approaches on pulmonary and cognitive function of patients undergoing CABG.

Methods:

Neuropsychological and pulmonary function tests were applied, prior to and following CABG, to 39 patients randomized into two groups as follows: Group 1 (control) – 20 patients underwent one physiotherapy session daily; and Group 2 (intensive physiotherapy) – 19 patients underwent three physiotherapy sessions daily during the recovery phase at the hospital. Non-paired and paired Student t tests were used to compare continuous variables. Variables without normal distribution were compared between groups by using Mann-Whitney test, and, within the same group at different times, by using Wilcoxon test. The chi-square test assessed differences of categorical variables. Statistical tests with a p value ≤ 0.05 were considered significant.

Results:

Changes in pulmonary function were not significantly different between the groups. However, while Group 2 patients showed no decline in their neurocognitive function, Group 1 patients showed a decline in their cognitive functions (P ≤ 0.01).

Conclusion:

Those results highlight the importance of physiotherapy after CABG and support the implementation of multiple sessions per day, providing patients with better psychosocial conditions and less morbidity.

  • Myocardial Revascularization / rehabilitation
  • Physical Therapy Speciality
  • Postoperative Care
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28/10/2014 DOI: 10.5935/abc.20140161 Views 1
Figure 1
Original Article

Physical Stress Echocardiography: Prediction of Mortality and Cardiac Events in Patients with Exercise Test showing Ischemia

Ana Carla Pereira de Araujo et al. Bruno F. de Oliveira Santos Flavia Ricci Calasans Ibraim M. Francisco Pinto … Daniel Pio de Oliveira Luiza Dantas Melo Stephanie Macedo Andrade Irlaneide da Silva Tavares Antonio Carlos Sobral Sousa Joselina Luzia Menezes Oliveira

Background:

Studies have demonstrated the diagnostic accuracy and prognostic value of physical stress echocardiography in coronary artery disease. However, the prediction of mortality and major cardiac events in patients with exercise test positive for myocardial ischemia is limited.

Objective:

To evaluate the effectiveness of physical stress echocardiography in the prediction of mortality and major cardiac events in patients with exercise test positive for myocardial ischemia.

Methods:

This is a retrospective cohort in which 866 consecutive patients with exercise test positive for myocardial ischemia, and who underwent physical stress echocardiography were studied. Patients were divided into two groups: with physical stress echocardiography negative (G1) or positive (G2) for myocardial ischemia. The endpoints analyzed were all-cause mortality and major cardiac events, defined as cardiac death and non-fatal acute myocardial infarction.

Results:

G2 comprised 205 patients (23.7%). During the mean 85.6 ± 15.0-month follow-up, there were 26 deaths, of which six were cardiac deaths, and 25 non-fatal myocardial infarction cases. The independent predictors of mortality were: age, diabetes mellitus, and positive physical stress echocardiography (hazard ratio: 2.69; 95% confidence interval: 1.20 – 6.01; p = 0.016). The independent predictors of major cardiac events were: age, previous coronary artery disease, positive physical stress echocardiography (hazard ratio: 2.75; 95% confidence interval: 1.15 – 6.53; p = 0.022) and absence of a 10% increase in ejection fraction. All-cause mortality and the incidence of major cardiac events were significantly higher in G2 (p < 0. 001 and p = 0.001, respectively).

Conclusion:

Physical stress echocardiography provides additional prognostic information in patients with exercise test positive for myocardial ischemia.

  • Coronary Artery Disease
  • Echocardiography,Stress/mortality
  • Exercise Test
  • Myocardial Ischemia
  • Physical Exertion
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28/10/2014 DOI: 10.5935/abc.20140144 Views 1
Figure 1
Review Article

Effects of Yoga in Patients with Chronic Heart Failure: A Meta-Analysis

Mansueto Gomes-Neto et al. Erenaldo Sousa Rodrigues-Jr Walderi Monteiro Silva-Jr Vitor Oliveira Carvalho

The use of yoga as an effective cardiac rehabilitation in patients with chronic heart failure (CHF) remains controversial.

We performed a meta-analysis to examine the effects of yoga on exercise capacity and health-related quality of life (HRQOL) in patients with CHF. Methods: We searched MEDLINE, Cochrane Central Register of Controlled Trials, Excerpta Medica database, LILACS, Physiotherapy Evidence Database, The Scientific Electronic Library Online, and Cumulative Index to Nursing and Allied Health (from the earliest date available to December 2013) for randomized controlled trials (RCTs) examining the effects of yoga versus exercise and/or of yoga versus control on exercise capacity (peakVO2) and quality-of-life (HRQOL) in CHF. Two reviewers selected studies independently. Weighted mean differences (WMDs) and 95% confidence intervals (CIs) were calculated, and heterogeneity was assessed using the I2 test.

Two studies met the selection criteria (total: 30 yoga and 29 control patients). The results suggested that yoga compared with control had a positive impact on peak VO2 and HRQOL. Peak VO2, WMD (3.87 95% CI: 1.95 to 5.80), and global HRQOL standardized mean differences (-12.46 95% CI: -22.49 to -2.43) improved in the yoga group compared to the control group.

Yoga enhances peak VO2 and HRQOL in patients with CHF and could be considered for inclusion in cardiac rehabilitation programs. Larger RCTs are required to further investigate the effects of yoga in patients with CHF.

  • Complementary Therapies/utilization
  • Exercise Therapy
  • Heart Failure
  • Meta-Analysis
  • Yoga
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10/10/2014 DOI: 10.5935/abc.20140149
Graph 1
Original Article

Hemodynamic Effects of Noninvasive Ventilation in Patients with Venocapillary Pulmonary Hypertension

André Moreira Bento et al. Luiz Francisco Cardoso Flávio Tarasoutchi Roney Orismar Sampaio … Luiz Junya Kajita Pedro Alves Lemos Neto

Background:

The hemodynamic effects of noninvasive ventilation with positive pressure in patients with pulmonary hypertension without left ventricular dysfunction are not clearly established.

Objectives:

Analyze the impact of increasing airway pressure with continuous positive airway pressure on hemodynamic parameters and, in particular, on cardiac output in patients with variable degrees of pulmonary hypertension.

Methods:

The study included 38 patients with pulmonary hypertension caused by mitral stenosis without left ventricular dysfunction or other significant valvulopathy. The hemodynamic state of these patients was analyzed in three conditions: baseline, after continuous positive pressure of 7 cmH2O and, finally, after pressure of 14 cmH2O.

Results:

The population was composed of predominantly young and female individuals with significant elevation in pulmonary arterial pressure (mean systolic pressure of 57 mmHg). Of all variables analyzed, only the right atrial pressure changed across the analyzed moments (from the baseline condition to the pressure of 14 cmH2O there was a change from 8 ± 4 mmHg to 11 ± 3 mmHg, respectively, p = 0.031). Even though there was no variation in mean cardiac output, increased values in pulmonary artery pressure were associated with increased cardiac output. There was no harmful effect or other clinical instability associated with use application of airway pressure.

Conclusion:

In patients with venocapillary pulmonary hypertension without left ventricular dysfunction, cardiac output response was directly associated with the degree of pulmonary hypertension. The application of noninvasive ventilation did not cause complications directly related to the ventilation systems.

  • Heart Failure
  • Hemodynamics
  • Hypertension
  • Noninvasive Ventilation
  • Pulmonary
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10/10/2014 DOI: 10.5935/abc.20140147
Figure 1
Original Article

Congenital Heart Disease as a Warning Sign for the Diagnosis of the 22q11.2 Deletion

Marcília S. Grassi et al. Cristina M. A. Jacob Leslie D. Kulikowski Antonio C. Pastorino … Roberta L. Dutra Nana Miura Marcelo B. Jatene Stephanie P. Pegler Chong A. Kim Magda Carneiro-Sampaio

Background:

To alert for the diagnosis of the 22q11.2 deletion syndrome (22q11.2DS) in patients with congenital heart disease (CHD).

Objective:

To describe the main CHDs, as well as phenotypic, metabolic and immunological findings in a series of 60 patients diagnosed with 22q11.2DS.

Methods:

The study included 60 patients with 22q11.2DS evaluated between 2007 and 2013 (M:F=1.3, age range 14 days to 20 years and 3 months) at a pediatric reference center for primary immunodeficiencies. The diagnosis was established by detection of the 22q11.2 microdeletion using FISH (n = 18) and/or MLPA (n = 42), in association with clinical and laboratory information. Associated CHDs, progression of phenotypic facial features, hypocalcemia and immunological changes were analyzed.

Results:

CHDs were detected in 77% of the patients and the most frequent type was tetralogy of Fallot (38.3%). Surgical correction of CHD was performed in 34 patients. Craniofacial dysmorphisms were detected in 41 patients: elongated face (60%) and/or elongated nose (53.3%), narrow palpebral fissure (50%), dysplastic, overfolded ears (48.3%), thin lips (41.6%), elongated fingers (38.3%) and short stature (36.6%). Hypocalcemia was detected in 64.2% and decreased parathyroid hormone (PTH) level in 25.9%. Decrease in total lymphocytes, CD4 and CD8 counts were present in 40%, 53.3% and 33.3%, respectively. Hypogammaglobulinemia was detected in one patient and decreased concentrations of immunoglobulin M (IgM) in two other patients.

Conclusion:

Suspicion for 22q11.2DS should be raised in all patients with CHD associated with hypocalcemia and/or facial dysmorphisms, considering that many of these changes may evolve with age. The 22q11.2 microdeletion should be confirmed by molecular testing in all patients.

  • Chromosomes
  • Congenital
  • Crromosome Delection
  • DiGeorge Syndrme
  • Heart Defects
  • human
  • Hypocalcemia
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10/10/2014 DOI: 10.5935/abc.20140145 Views 1
Original Article

Applicability of the Appropriate use Criteria for Myocardial Perfusion Scintigraphy

Anderson de Oliveira et al. Maria Fernanda Rezende Renato Corrêa Rodrigo Mousinho … Jader Cunha Azevedo Sandra Marina Miranda Aline Ribeiro Oliveira Ricardo Fraga Gutterres Evandro Tinoco Mesquita Cláudio Tinoco Mesquita

Background:

Appropriateness Criteria for nuclear imaging exams were created by American College of Cardiology (ACC) e American Society of Nuclear Cardiology (ASNC) to allow the rational use of tests. Little is known whether these criteria have been followed in clinical practice.

Objective:

To evaluate whether the medical applications of myocardial perfusion scintigraphy (MPS) in a private nuclear medicine service of a tertiary cardiology hospital were suitable to the criteria of indications proposed by the American medical societies in 2005 and 2009 and compare the level of indication of both.

Methods:

We included records of 383 patients that underwent MPS, November 2008 up to February 2009. Demographic characteristics, patient’s origin, coronary risk factors, time of medical graduation and appropriateness criteria of medical applications were studied. The criteria were evaluated by two independent physicians and, in doubtful cases, defined by a medical expert in MPS.

Results:

Mean age was 65 ± 12 years. Of the 367 records reviewed, 236 (64.3%) studies were performed in men and 75 (20.4%) were internee. To ACC 2005, 255 (69.5%) were considered appropriate indication and 13 (3.5%) inappropriate. With ACC 2009, 249 (67.8%) were considered appropriate indications and 13 (5.2%) inappropriate.

Conclusions:

We observed a high rate of adequacy of medical indications for MPS. Compared to the 2005 version, 2009 did not change the results.

  • Diagnostic Imaging
  • Myocardial Perfusion Imaging
  • Myocardial/radionuclide imaging
  • Quality of Health Care
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23/09/2014 DOI: 10.5935/abc.20140140
Original Article

Sleep Apnea and Nocturnal Cardiac Arrhythmia: A Populational Study

Fatima Dumas Cintra et al. Renata Pimentel Leite Luciana Julio Storti Lia Azeredo Bittencourt … Dalva Poyares Laura de Siqueira Castro Sergio Tufik Angelo de Paola

Background:

The mechanisms associated with the cardiovascular consequences of obstructive sleep apnea include abrupt changes in autonomic tone, which can trigger cardiac arrhythmias. The authors hypothesized that nocturnal cardiac arrhythmia occurs more frequently in patients with obstructive sleep apnea.

Objective:

To analyze the relationship between obstructive sleep apnea and abnormal heart rhythm during sleep in a population sample.

Methods:

Cross-sectional study with 1,101 volunteers, who form a representative sample of the city of São Paulo. The overnight polysomnography was performed using an EMBLA® S7000 digital system during the regular sleep schedule of the individual. The electrocardiogram channel was extracted, duplicated, and then analyzed using a Holter (Cardio Smart®) system.

Results:

A total of 767 participants (461 men) with a mean age of 42.00 ± 0.53 years, were included in the analysis. At least one type of nocturnal cardiac rhythm disturbance (atrial/ventricular arrhythmia or beat) was observed in 62.7% of the sample. The occurrence of nocturnal cardiac arrhythmias was more frequent with increased disease severity. Rhythm disturbance was observed in 53.3% of the sample without breathing sleep disorders, whereas 92.3% of patients with severe obstructive sleep apnea showed cardiac arrhythmia. Isolated atrial and ventricular ectopy was more frequent in patients with moderate/severe obstructive sleep apnea when compared to controls (p < 0.001). After controlling for potential confounding factors, age, sex and apnea-hypopnea index were associated with nocturnal cardiac arrhythmia.

Conclusion:

Nocturnal cardiac arrhythmia occurs more frequently in patients with obstructive sleep apnea and the prevalence increases with disease severity. Age, sex, and the Apnea-hypopnea index were predictors of arrhythmia in this sample.

  • Arrhythmias Cardiac
  • Sleep
  • Sleep apnea syndromes
  • Sleep Apnea, Obstructive
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23/09/2014 DOI: 10.5935/abc.20140142 Views 2
Original Article

Association of Aortic Valve Sclerosis with Previous Coronary Artery Disease and Risk Factors

Filipe Carvalho Marmelo et al. Sónia Matilde Fonseca Mateus Alexandre José Marques Pereira

Background:

Aortic valve sclerosis (AVS) is characterized by increased thickness, calcification and stiffness of the aortic leaflets without fusion of the commissures. Several studies show an association between AVS and presence of coronary artery disease.

Objective:

The aim of this study is to investigate the association between presence of AVS with occurrence of previous coronary artery disease and classical risk factors.

Methods:

The sample was composed of 2,493 individuals who underwent transthoracic echocardiography between August 2011 and December 2012. The mean age of the cohort was 67.5 ± 15.9 years, and 50.7% were female.

Results:

The most frequent clinical indication for Doppler echocardiography was the presence of stroke (28.8%), and the most common risk factor was hypertension (60.8%). The most prevalent pathological findings on Doppler echocardiography were mitral valve sclerosis (37.1%) and AVS (36.7%). There was a statistically significant association between AVS with hypertension (p < 0.001), myocardial infarction (p = 0.007), diabetes (p = 0.006) and compromised left ventricular systolic function (p < 0.001). Conclusion: Patients with AVS have higher prevalences of hypertension, stroke, hypercholesterolemia, myocardial infarction, diabetes and compromised left ventricular systolic function when compared with patients without AVS. We conclude that there is an association between presence of AVS with previous coronary artery disease and classical risk factors.

  • Coronary Artery Disease
  • Echocardiography, Doppler
  • Heart Valve Disease/physopathology
  • Risk Factors
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12/09/2014 DOI: 10.5935/abc.20140136
Figure 1
Original Article

Prevention of Pazopanib-Induced Prolonged Cardiac Repolarization and Proarrhythmic Effects

Tulay Akman et al. Oytun Erbas Levent Akman Ahmet U. Yilmaz

Background:

Pazopanib (PZP) may induce prolonged cardiac repolarization and proarrhythmic effects, similarly to other tyrosine kinase inhibitors.

Objectives:

To demonstrate PZP-induced prolonged cardiac repolarization and proarrhythmic electrophysiological effects and to investigate possible preventive effects of metoprolol and diltiazem on ECG changes (prolonged QT) in an experimental rat model.

Methods:

Twenty-four Sprague-Dawley adult male rats were randomly assigned to 4 groups (n = 6). The first group (normal group) received 4 mL of tap water and the other groups received 100 mg/kg of PZP (Votrient® tablet) perorally, via orogastric tubes. After 3 hours, the following solutions were intraperitoneally administered to the animals: physiological saline solution (SP), to the normal group and to the second group (control-PZP+SP group); 1 mg/kg metoprolol (Beloc, Ampule, AstraZeneca), to the third group (PZP+metoprolol group); and 1mg/kg diltiazem (Diltiazem, Mustafa Nevzat), to the fourth group (PZP+diltiazem group). One hour after, and under anesthesia, QTc was calculated by recording ECG on lead I.

Results:

The mean QTc interval values were as follows: normal group, 99.93 ± 3.62 ms; control-PZP+SP group, 131.23 ± 12.21 ms; PZP+metoprolol group, 89.36 ± 3.61 ms; and PZP+diltiazem group, 88.86 ± 4.04 ms. Both PZP+metoprolol and PZP+diltiazem groups had significantly shorter QTc intervals compared to the control-PZP+SP group (p < 0.001).

Conclusion:

Both metoprolol and diltiazem prevented PZP-induced QT interval prolongation. These drugs may provide a promising prophylactic strategy for the prolonged QTc interval associated with tyrosine kinase inhibitor use.

  • Arrhythmias, Cardiac/therapy
  • Heart / physiology
  • Heart Conduction System / physiology
  • Pyrimidines / adverse effects
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12/09/2014 DOI: 10.5935/abc.20140138
Original Article

Determinants of Functional and Structural Properties of Large Arteries in Healthy Individuals

Elaine Cristina Tolezani et al. Valéria Costa-Hong Gustavo Correia Alfredo José Mansur … Luciano Ferreira Drager Luiz Aparecido Bortolotto

Background:

Changes in the properties of large arteries correlate with higher cardiovascular risk. Recent guidelines have included the assessment of those properties to detect subclinical disease. Establishing reference values for the assessment methods as well as determinants of the arterial parameters and their correlations in healthy individuals is important to stratify patients.

Objective:

To assess, in healthy adults, the distribution of the values of pulse wave velocity, diameter, intima-media thickness and relative distensibility of the carotid artery, in addition to assessing the demographic and clinical determinants of those parameters and their correlations.

Methods:

This study evaluated 210 individuals (54% women; mean age, 44 ± 13 years) with no evidence of cardiovascular disease. The carotid-femoral pulse wave velocity was measured with a Complior® device. The functional and structural properties of the carotid artery were assessed by using radiofrequency ultrasound.

Results:

The means of the following parameters were: pulse wave velocity, 8.7 ± 1.5 m/s; diameter, 6,707.9 ± 861.6 μm; intima-media thickness, 601 ± 131 μm; relative distensibility, 5.3 ± 2.1%. No significant difference related to sex or ethnicity was observed. On multiple linear logistic regression, the factors independently related to the vascular parameters were: pulse wave velocity, to age (p < 0.01) and triglycerides (p = 0.02); intima-media thickness, to age (p < 0.01); diameter, to creatinine (p = 0.03) and age (p = 0.02); relative distensibility, to age (p < 0.01) and systolic and diastolic blood pressures (p = 0.02 and p = 0.01, respectively). Pulse wave velocity showed a positive correlation with intima media thickness (p < 0.01) and with relative distensibility (p < 0.01), while diameter showed a positive correlation with distensibility (p = 0.03).

Conclusion:

In healthy individuals, age was the major factor related to aortic stiffness, while age and diastolic blood pressure related to the carotid functional measure. The carotid artery structure was directly related to aortic stiffness, which was inversely related to the carotid artery functional property.

  • Arterial Pressure
  • Arteries
  • Carotid Intima-Media Thickness
  • Pulse Wave Analysis
  • Vascular Stiffness
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29/08/2014 DOI: 10.5935/abc.20140124 Views 1

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Lima EG, Vieira RD, Bombonati P, Castelli JB. Case 5/2014 – 41-Year-Old Woman with Rheumatic Disease and Previous Mitral Valve Repair with Pulmonary Embolism and Cardiogenic and Septic Shock. Arquivos Brasileiros de Cardiologia 2014;103(5):e57.

Electronic Document Format (ABNT)

Lima, Eduardo Gomes; Vieira, Ricardo D’Oliveira; Bombonati, Paula; Castelli, Jussara Bianchi. Case 5/2014 – 41-Year-Old Woman with Rheumatic Disease and Previous Mitral Valve Repair with Pulmonary Embolism and Cardiogenic and Septic Shock. Arquivos Brasileiros de Cardiologia, v. 103, n. 5, e57, Oct. 2014.

Electronic Document Format (APA)

Lima, E. G., Vieira, R. D., Bombonati, P., & Castelli, J. B. (2014). Case 5/2014 – 41-Year-Old Woman with Rheumatic Disease and Previous Mitral Valve Repair with Pulmonary Embolism and Cardiogenic and Septic Shock. Arquivos Brasileiros de Cardiologia, 103(5), e57.

Electronic Document Format (ISO)

Lima, Eduardo Gomes and Vieira, Ricardo D’Oliveira and Bombonati, Paula and Castelli, Jussara Bianchi. Case 5/2014 – 41-Year-Old Woman with Rheumatic Disease and Previous Mitral Valve Repair with Pulmonary Embolism and Cardiogenic and Septic Shock. Arquivos Brasileiros de Cardiologia [online]. 2014, vol. 103, n. 5, [cited 2026-10-14], e57. Available from: <https://journals.cardiol.br/en/article/case-5-2014-41-year-old-woman-with-rheumatic-disease-and-previous-mitral-valve-repair-with-pulmonary-embolism-and-cardiogenic-and-septic-shock/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Nacif MS, Rochitte CE. Cardiovascular Computed Tomography and Magnetic Resonance: History and Growing Impact in Brazil and in the World. Arquivos Brasileiros de Cardiologia 2014;103(5):362-7.

Electronic Document Format (ABNT)

Nacif, Marcelo Souto; Rochitte, Carlos Eduardo. Cardiovascular Computed Tomography and Magnetic Resonance: History and Growing Impact in Brazil and in the World. Arquivos Brasileiros de Cardiologia, v. 103, n. 5, p. 362-367, Oct. 2014.

Electronic Document Format (APA)

Nacif, M. S., & Rochitte, C. E. (2014). Cardiovascular Computed Tomography and Magnetic Resonance: History and Growing Impact in Brazil and in the World. Arquivos Brasileiros de Cardiologia, 103(5), 362-367.

Electronic Document Format (ISO)

Nacif, Marcelo Souto and Rochitte, Carlos Eduardo. Cardiovascular Computed Tomography and Magnetic Resonance: History and Growing Impact in Brazil and in the World. Arquivos Brasileiros de Cardiologia [online]. 2014, vol. 103, n. 5, [cited 2026-10-14], pp. 362-367. Available from: <https://journals.cardiol.br/en/article/cardiovascular-computed-tomography-and-magnetic-resonance-history-and-growing-impact-in-brazil-and-in-the-world/>. ISSN 0066-782X

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. Edition of March 2014, vol. 102 (3), Supl. 1, pg. 1-61. Arquivos Brasileiros de Cardiologia 2014;103(5):443.

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. Edition of March 2014, vol. 102 (3), Supl. 1, pg. 1-61. Arquivos Brasileiros de Cardiologia, v. 103, n. 5, p. 443-443, Oct. 2014.

Electronic Document Format (APA)

(2014). Edition of March 2014, vol. 102 (3), Supl. 1, pg. 1-61. Arquivos Brasileiros de Cardiologia, 103(5), 443-443.

Electronic Document Format (ISO)

. Edition of March 2014, vol. 102 (3), Supl. 1, pg. 1-61. Arquivos Brasileiros de Cardiologia [online]. 2014, vol. 103, n. 5, [cited 2026-10-14], pp. 443-443. Available from: <https://journals.cardiol.br/en/article/edition-of-march-2014-vol-102-3-supl-1-pg-1-61/>. ISSN 0066-782X

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an DY. ACE I/D Gene Polymorphism in Children with Family History of Premature Coronary Disease. Arquivos Brasileiros de Cardiologia 2014;103(5):440-2.

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an, Dilek Yý lmaz Çiftdoð. ACE I/D Gene Polymorphism in Children with Family History of Premature Coronary Disease. Arquivos Brasileiros de Cardiologia, v. 103, n. 5, p. 440-442, Oct. 2014.

Electronic Document Format (APA)

an, D. Y. (2014). ACE I/D Gene Polymorphism in Children with Family History of Premature Coronary Disease. Arquivos Brasileiros de Cardiologia, 103(5), 440-442.

Electronic Document Format (ISO)

an, Dilek Yý lmaz Çiftdoð. ACE I/D Gene Polymorphism in Children with Family History of Premature Coronary Disease. Arquivos Brasileiros de Cardiologia [online]. 2014, vol. 103, n. 5, [cited 2026-10-14], pp. 440-442. Available from: <https://journals.cardiol.br/en/article/ace-i-d-gene-polymorphism-in-children-with-family-history-of-premature-coronary-disease/>. ISSN 0066-782X

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Hossri CAC, Queiroga Júnior FJP, Carvalho VO, Carvalho CRR, Albuquerque ALP. Multiple Benefits of Rehabilitation in a Patient with Heart and Renal Failure. Arquivos Brasileiros de Cardiologia 2014;103(5):e68.

Electronic Document Format (ABNT)

Hossri, Carlos Alberto Cordeiro; Queiroga Júnior, Fernando José Pinho; Carvalho, Vitor Oliveira; Carvalho, Carlos Roberto Ribeiro; Albuquerque, Andre Luis Pereira. Multiple Benefits of Rehabilitation in a Patient with Heart and Renal Failure. Arquivos Brasileiros de Cardiologia, v. 103, n. 5, e68, Oct. 2014.

Electronic Document Format (APA)

Hossri, C. A. C., Queiroga Júnior, F. J. P., Carvalho, V. O., Carvalho, C. R. R., & Albuquerque, A. L. P. (2014). Multiple Benefits of Rehabilitation in a Patient with Heart and Renal Failure. Arquivos Brasileiros de Cardiologia, 103(5), e68.

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Hossri, Carlos Alberto Cordeiro and Queiroga Júnior, Fernando José Pinho and Carvalho, Vitor Oliveira and Carvalho, Carlos Roberto Ribeiro and Albuquerque, Andre Luis Pereira. Multiple Benefits of Rehabilitation in a Patient with Heart and Renal Failure. Arquivos Brasileiros de Cardiologia [online]. 2014, vol. 103, n. 5, [cited 2026-10-14], e68. Available from: <https://journals.cardiol.br/en/article/multiple-benefits-of-rehabilitation-in-a-patient-with-heart-and-renal-failure/>. ISSN 0066-782X

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Petrou E, Iakovou I. Left Internal Mammary Artery Graft-to-Pulmonary Artery Fistula. Arquivos Brasileiros de Cardiologia 2014;103(5):e72.

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Petrou, Emmanouil; Iakovou, Ioannis. Left Internal Mammary Artery Graft-to-Pulmonary Artery Fistula. Arquivos Brasileiros de Cardiologia, v. 103, n. 5, e72, Oct. 2014.

Electronic Document Format (APA)

Petrou, E., & Iakovou, I. (2014). Left Internal Mammary Artery Graft-to-Pulmonary Artery Fistula. Arquivos Brasileiros de Cardiologia, 103(5), e72.

Electronic Document Format (ISO)

Petrou, Emmanouil and Iakovou, Ioannis. Left Internal Mammary Artery Graft-to-Pulmonary Artery Fistula. Arquivos Brasileiros de Cardiologia [online]. 2014, vol. 103, n. 5, [cited 2026-10-14], e72. Available from: <https://journals.cardiol.br/en/article/left-internal-mammary-artery-graft-to-pulmonary-artery-fistula/>. ISSN 0066-782X

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Cavalcante ES, Magario R, Conforti CA, Cipriano Júnior G, Arena R, Carvalho ACC, Buffolo E, et al. Impact of Intensive Physiotherapy on Cognitive Function after Coronary Artery Bypass Graft Surgery. Arquivos Brasileiros de Cardiologia 2014;103(5):391-7.

Electronic Document Format (ABNT)

Cavalcante, Elder dos Santos; Magario, Rosmeiri; Conforti, César Augusto; Cipriano Júnior, Gerson; Arena, Ross; Carvalho, Antonio Carlos C.; Buffolo, Enio; Luna Filho, Bráulio. Impact of Intensive Physiotherapy on Cognitive Function after Coronary Artery Bypass Graft Surgery. Arquivos Brasileiros de Cardiologia, v. 103, n. 5, p. 391-397, Oct. 2014.

Electronic Document Format (APA)

Cavalcante, E. S., Magario, R., Conforti, C. A., Cipriano Júnior, G., Arena, R., Carvalho, A. C. C., Buffolo, E., & Luna Filho, B. (2014). Impact of Intensive Physiotherapy on Cognitive Function after Coronary Artery Bypass Graft Surgery. Arquivos Brasileiros de Cardiologia, 103(5), 391-397.

Electronic Document Format (ISO)

Cavalcante, Elder dos Santos and Magario, Rosmeiri and Conforti, César Augusto and Cipriano Júnior, Gerson and Arena, Ross and Carvalho, Antonio Carlos C. and Buffolo, Enio and Luna Filho, Bráulio. Impact of Intensive Physiotherapy on Cognitive Function after Coronary Artery Bypass Graft Surgery. Arquivos Brasileiros de Cardiologia [online]. 2014, vol. 103, n. 5, [cited 2026-10-14], pp. 391-397. Available from: <https://journals.cardiol.br/en/article/impact-of-intensive-physiotherapy-on-cognitive-function-after-coronary-artery-bypass-graft-surgery/>. ISSN 0066-782X

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Araujo ACP, Santos BFO, Calasans FR, Pinto IMF, Oliveira DP, Melo LD, Andrade SM, et al. Physical Stress Echocardiography: Prediction of Mortality and Cardiac Events in Patients with Exercise Test showing Ischemia. Arquivos Brasileiros de Cardiologia 2014;103(5):418-25.

Electronic Document Format (ABNT)

Araujo, Ana Carla Pereira de; Santos, Bruno F. de Oliveira; Calasans, Flavia Ricci; Pinto, Ibraim M. Francisco; Oliveira, Daniel Pio de; Melo, Luiza Dantas; Andrade, Stephanie Macedo; Tavares, Irlaneide da Silva; Sousa, Antonio Carlos Sobral; Oliveira, Joselina Luzia Menezes. Physical Stress Echocardiography: Prediction of Mortality and Cardiac Events in Patients with Exercise Test showing Ischemia. Arquivos Brasileiros de Cardiologia, v. 103, n. 5, p. 418-425, Oct. 2014.

Electronic Document Format (APA)

Araujo, A. C. P. , Santos, B. F. O., Calasans, F. R., Pinto, I. M. F., Oliveira, D. P. , Melo, L. D., Andrade, S. M., Tavares, I. S., Sousa, A. C. S., & Oliveira, J. L. M. (2014). Physical Stress Echocardiography: Prediction of Mortality and Cardiac Events in Patients with Exercise Test showing Ischemia. Arquivos Brasileiros de Cardiologia, 103(5), 418-425.

Electronic Document Format (ISO)

Araujo, Ana Carla Pereira de and Santos, Bruno F. de Oliveira and Calasans, Flavia Ricci and Pinto, Ibraim M. Francisco and Oliveira, Daniel Pio de and Melo, Luiza Dantas and Andrade, Stephanie Macedo and Tavares, Irlaneide da Silva and Sousa, Antonio Carlos Sobral and Oliveira, Joselina Luzia Menezes. Physical Stress Echocardiography: Prediction of Mortality and Cardiac Events in Patients with Exercise Test showing Ischemia. Arquivos Brasileiros de Cardiologia [online]. 2014, vol. 103, n. 5, [cited 2026-10-14], pp. 418-425. Available from: <https://journals.cardiol.br/en/article/physical-stress-echocardiography-prediction-of-mortality-and-cardiac-events-in-patients-with-exercise-test-showing-ischemia/>. ISSN 0066-782X

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Gomes-Neto M, Rodrigues-Jr ES, Silva-Jr WM, Carvalho VO. Effects of Yoga in Patients with Chronic Heart Failure: A Meta-Analysis. Arquivos Brasileiros de Cardiologia 2014;103(5):433-9.

Electronic Document Format (ABNT)

Gomes-Neto, Mansueto; Rodrigues-Jr, Erenaldo Sousa; Silva-Jr, Walderi Monteiro; Carvalho, Vitor Oliveira. Effects of Yoga in Patients with Chronic Heart Failure: A Meta-Analysis. Arquivos Brasileiros de Cardiologia, v. 103, n. 5, p. 433-439, Oct. 2014.

Electronic Document Format (APA)

Gomes-Neto, M., Rodrigues-Jr, E. S., Silva-Jr, W. M., & Carvalho, V. O. (2014). Effects of Yoga in Patients with Chronic Heart Failure: A Meta-Analysis. Arquivos Brasileiros de Cardiologia, 103(5), 433-439.

Electronic Document Format (ISO)

Gomes-Neto, Mansueto and Rodrigues-Jr, Erenaldo Sousa and Silva-Jr, Walderi Monteiro and Carvalho, Vitor Oliveira. Effects of Yoga in Patients with Chronic Heart Failure: A Meta-Analysis. Arquivos Brasileiros de Cardiologia [online]. 2014, vol. 103, n. 5, [cited 2026-10-14], pp. 433-439. Available from: <https://journals.cardiol.br/en/article/effects-of-yoga-in-patients-with-chronic-heart-failure-a-meta-analysis/>. ISSN 0066-782X

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Bento AM, Cardoso LF, Tarasoutchi F, Sampaio RO, Kajita LJ, Lemos Neto PA. Hemodynamic Effects of Noninvasive Ventilation in Patients with Venocapillary Pulmonary Hypertension. Arquivos Brasileiros de Cardiologia 2014;103(5):410-7.

Electronic Document Format (ABNT)

Bento, André Moreira; Cardoso, Luiz Francisco; Tarasoutchi, Flávio; Sampaio, Roney Orismar; Kajita, Luiz Junya; Lemos Neto, Pedro Alves. Hemodynamic Effects of Noninvasive Ventilation in Patients with Venocapillary Pulmonary Hypertension. Arquivos Brasileiros de Cardiologia, v. 103, n. 5, p. 410-417, Oct. 2014.

Electronic Document Format (APA)

Bento, A. M., Cardoso, L. F., Tarasoutchi, F., Sampaio, R. O., Kajita, L. J., & Lemos Neto, P. A. (2014). Hemodynamic Effects of Noninvasive Ventilation in Patients with Venocapillary Pulmonary Hypertension. Arquivos Brasileiros de Cardiologia, 103(5), 410-417.

Electronic Document Format (ISO)

Bento, André Moreira and Cardoso, Luiz Francisco and Tarasoutchi, Flávio and Sampaio, Roney Orismar and Kajita, Luiz Junya and Lemos Neto, Pedro Alves. Hemodynamic Effects of Noninvasive Ventilation in Patients with Venocapillary Pulmonary Hypertension. Arquivos Brasileiros de Cardiologia [online]. 2014, vol. 103, n. 5, [cited 2026-10-14], pp. 410-417. Available from: <https://journals.cardiol.br/en/article/hemodynamic-effects-of-noninvasive-ventilation-in-patients-with-venocapillary-pulmonary-hypertension/>. ISSN 0066-782X

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Electronic Document Format (Vancouver)

Grassi MS, Jacob CMA, Kulikowski LD, Pastorino AC, Dutra RL, Miura N, Jatene MB, et al. Congenital Heart Disease as a Warning Sign for the Diagnosis of the 22q11.2 Deletion. Arquivos Brasileiros de Cardiologia 2014;103(5):382-90.

Electronic Document Format (ABNT)

Grassi, Marcília S.; Jacob, Cristina M. A.; Kulikowski, Leslie D.; Pastorino, Antonio C.; Dutra, Roberta L.; Miura, Nana; Jatene, Marcelo B.; Pegler, Stephanie P.; Kim, Chong A.; Carneiro-Sampaio, Magda. Congenital Heart Disease as a Warning Sign for the Diagnosis of the 22q11.2 Deletion. Arquivos Brasileiros de Cardiologia, v. 103, n. 5, p. 382-390, Oct. 2014.

Electronic Document Format (APA)

Grassi, M. S., Jacob, C. M. A., Kulikowski, L. D., Pastorino, A. C., Dutra, R. L., Miura, N., Jatene, M. B., Pegler, S. P., Kim, C. A., & Carneiro-Sampaio, M. (2014). Congenital Heart Disease as a Warning Sign for the Diagnosis of the 22q11.2 Deletion. Arquivos Brasileiros de Cardiologia, 103(5), 382-390.

Electronic Document Format (ISO)

Grassi, Marcília S. and Jacob, Cristina M. A. and Kulikowski, Leslie D. and Pastorino, Antonio C. and Dutra, Roberta L. and Miura, Nana and Jatene, Marcelo B. and Pegler, Stephanie P. and Kim, Chong A. and Carneiro-Sampaio, Magda. Congenital Heart Disease as a Warning Sign for the Diagnosis of the 22q11.2 Deletion. Arquivos Brasileiros de Cardiologia [online]. 2014, vol. 103, n. 5, [cited 2026-10-14], pp. 382-390. Available from: <https://journals.cardiol.br/en/article/congenital-heart-disease-as-a-warning-sign-for-the-diagnosis-of-the-22q11-2-deletion/>. ISSN 0066-782X

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Oliveira A, Rezende MF, Corrêa R, Mousinho R, Azevedo JC, Miranda SM, Oliveira AR, et al. Applicability of the Appropriate use Criteria for Myocardial Perfusion Scintigraphy. Arquivos Brasileiros de Cardiologia 2014;103(5):375-81.

Electronic Document Format (ABNT)

Oliveira, Anderson de; Rezende, Maria Fernanda; Corrêa, Renato; Mousinho, Rodrigo; Azevedo, Jader Cunha; Miranda, Sandra Marina; Oliveira, Aline Ribeiro; Gutterres, Ricardo Fraga; Mesquita, Evandro Tinoco; Mesquita, Cláudio Tinoco. Applicability of the Appropriate use Criteria for Myocardial Perfusion Scintigraphy. Arquivos Brasileiros de Cardiologia, v. 103, n. 5, p. 375-381, Sep. 2014.

Electronic Document Format (APA)

Oliveira, A. , Rezende, M. F., Corrêa, R., Mousinho, R., Azevedo, J. C., Miranda, S. M., Oliveira, A. R., Gutterres, R. F., Mesquita, E. T., & Mesquita, C. T. (2014). Applicability of the Appropriate use Criteria for Myocardial Perfusion Scintigraphy. Arquivos Brasileiros de Cardiologia, 103(5), 375-381.

Electronic Document Format (ISO)

Oliveira, Anderson de and Rezende, Maria Fernanda and Corrêa, Renato and Mousinho, Rodrigo and Azevedo, Jader Cunha and Miranda, Sandra Marina and Oliveira, Aline Ribeiro and Gutterres, Ricardo Fraga and Mesquita, Evandro Tinoco and Mesquita, Cláudio Tinoco. Applicability of the Appropriate use Criteria for Myocardial Perfusion Scintigraphy. Arquivos Brasileiros de Cardiologia [online]. 2014, vol. 103, n. 5, [cited 2026-10-14], pp. 375-381. Available from: <https://journals.cardiol.br/en/article/applicability-of-the-appropriate-use-criteria-for-myocardial-perfusion-scintigraphy/>. ISSN 0066-782X

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Electronic Document Format (Vancouver)

Cintra FD, Leite RP, Storti LJ, Bittencourt LA, Poyares D, Castro LS, Tufik S, et al. Sleep Apnea and Nocturnal Cardiac Arrhythmia: A Populational Study. Arquivos Brasileiros de Cardiologia 2014;103(5):368-74.

Electronic Document Format (ABNT)

Cintra, Fatima Dumas; Leite, Renata Pimentel; Storti, Luciana Julio; Bittencourt, Lia Azeredo; Poyares, Dalva; Castro, Laura de Siqueira; Tufik, Sergio; Paola, Angelo de. Sleep Apnea and Nocturnal Cardiac Arrhythmia: A Populational Study. Arquivos Brasileiros de Cardiologia, v. 103, n. 5, p. 368-374, Sep. 2014.

Electronic Document Format (APA)

Cintra, F. D., Leite, R. P., Storti, L. J., Bittencourt, L. A., Poyares, D., Castro, L. S., Tufik, S., & Paola, A. (2014). Sleep Apnea and Nocturnal Cardiac Arrhythmia: A Populational Study. Arquivos Brasileiros de Cardiologia, 103(5), 368-374.

Electronic Document Format (ISO)

Cintra, Fatima Dumas and Leite, Renata Pimentel and Storti, Luciana Julio and Bittencourt, Lia Azeredo and Poyares, Dalva and Castro, Laura de Siqueira and Tufik, Sergio and Paola, Angelo de. Sleep Apnea and Nocturnal Cardiac Arrhythmia: A Populational Study. Arquivos Brasileiros de Cardiologia [online]. 2014, vol. 103, n. 5, [cited 2026-10-14], pp. 368-374. Available from: <https://journals.cardiol.br/en/article/sleep-apnea-and-nocturnal-cardiac-arrhythmia-a-populational-study/>. ISSN 0066-782X

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Marmelo FC, Mateus SMF, Pereira AJM. Association of Aortic Valve Sclerosis with Previous Coronary Artery Disease and Risk Factors. Arquivos Brasileiros de Cardiologia 2014;103(5):398-402.

Electronic Document Format (ABNT)

Marmelo, Filipe Carvalho; Mateus, Sónia Matilde Fonseca; Pereira, Alexandre José Marques. Association of Aortic Valve Sclerosis with Previous Coronary Artery Disease and Risk Factors. Arquivos Brasileiros de Cardiologia, v. 103, n. 5, p. 398-402, Sep. 2014.

Electronic Document Format (APA)

Marmelo, F. C., Mateus, S. M. F., & Pereira, A. J. M. (2014). Association of Aortic Valve Sclerosis with Previous Coronary Artery Disease and Risk Factors. Arquivos Brasileiros de Cardiologia, 103(5), 398-402.

Electronic Document Format (ISO)

Marmelo, Filipe Carvalho and Mateus, Sónia Matilde Fonseca and Pereira, Alexandre José Marques. Association of Aortic Valve Sclerosis with Previous Coronary Artery Disease and Risk Factors. Arquivos Brasileiros de Cardiologia [online]. 2014, vol. 103, n. 5, [cited 2026-10-14], pp. 398-402. Available from: <https://journals.cardiol.br/en/article/association-of-aortic-valve-sclerosis-with-previous-coronary-artery-disease-and-risk-factors/>. ISSN 0066-782X

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Akman T, Erbas O, Akman L, Yilmaz AU. Prevention of Pazopanib-Induced Prolonged Cardiac Repolarization and Proarrhythmic Effects. Arquivos Brasileiros de Cardiologia 2014;103(5):403-9.

Electronic Document Format (ABNT)

Akman, Tulay; Erbas, Oytun; Akman, Levent; Yilmaz, Ahmet U.. Prevention of Pazopanib-Induced Prolonged Cardiac Repolarization and Proarrhythmic Effects. Arquivos Brasileiros de Cardiologia, v. 103, n. 5, p. 403-409, Sep. 2014.

Electronic Document Format (APA)

Akman, T., Erbas, O., Akman, L., & Yilmaz, A. U. (2014). Prevention of Pazopanib-Induced Prolonged Cardiac Repolarization and Proarrhythmic Effects. Arquivos Brasileiros de Cardiologia, 103(5), 403-409.

Electronic Document Format (ISO)

Akman, Tulay and Erbas, Oytun and Akman, Levent and Yilmaz, Ahmet U.. Prevention of Pazopanib-Induced Prolonged Cardiac Repolarization and Proarrhythmic Effects. Arquivos Brasileiros de Cardiologia [online]. 2014, vol. 103, n. 5, [cited 2026-10-14], pp. 403-409. Available from: <https://journals.cardiol.br/en/article/prevention-of-pazopanib-induced-prolonged-cardiac-repolarization-and-proarrhythmic-effects/>. ISSN 0066-782X

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Electronic Document Format (Vancouver)

Tolezani EC, Costa-Hong V, Correia G, Mansur AJ, Drager LF, Bortolotto LA. Determinants of Functional and Structural Properties of Large Arteries in Healthy Individuals. Arquivos Brasileiros de Cardiologia 2014;103(5):426-32.

Electronic Document Format (ABNT)

Tolezani, Elaine Cristina; Costa-Hong, Valéria; Correia, Gustavo; Mansur, Alfredo José; Drager, Luciano Ferreira; Bortolotto, Luiz Aparecido. Determinants of Functional and Structural Properties of Large Arteries in Healthy Individuals. Arquivos Brasileiros de Cardiologia, v. 103, n. 5, p. 426-432, Aug. 2014.

Electronic Document Format (APA)

Tolezani, E. C., Costa-Hong, V., Correia, G., Mansur, A. J., Drager, L. F., & Bortolotto, L. A. (2014). Determinants of Functional and Structural Properties of Large Arteries in Healthy Individuals. Arquivos Brasileiros de Cardiologia, 103(5), 426-432.

Electronic Document Format (ISO)

Tolezani, Elaine Cristina and Costa-Hong, Valéria and Correia, Gustavo and Mansur, Alfredo José and Drager, Luciano Ferreira and Bortolotto, Luiz Aparecido. Determinants of Functional and Structural Properties of Large Arteries in Healthy Individuals. Arquivos Brasileiros de Cardiologia [online]. 2014, vol. 103, n. 5, [cited 2026-10-14], pp. 426-432. Available from: <https://journals.cardiol.br/en/article/determinants-of-functional-and-structural-properties-of-large-arteries-in-healthy-individuals/>. ISSN 0066-782X

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