ABC Family Arquivos Brasileiros de Cardiologia International Journal of Cardiovascular Sciences ABC Heart Failure & Cardiomyopathy ABC Imagem Cardiovascular
Português English
ABC Family
Português English
  • About
    • About ABC Family
    • Internal Regulation
    • Editorial Board
    • Brazilian Society of Cardiology (SBC)
  • Issues
  • SBC Guidelines
  • Content
    • Videos
    • Podcasts
    • News
  • About
    • About ABC Family
    • Internal Regulation
    • Editorial Board
    • Brazilian Society of Cardiology (SBC)
  • Issues
  • SBC Guidelines
  • Content
    • Videos
    • Podcasts
    • News

ABC Family

  • ABC Family
  • Arquivos Brasileiros de Cardiologia
  • International Journal of Cardiovascular Sciences
  • ABC Heart Failure & Cardiomyopathy
  • ABC Imagem Cardiovascular
Search in

No content found.

Journals
Ordering
Article types
Others

  1. Home
  2. Keyword: Frailty
Figure 1
IJCS
Original Article

Prevalence of Frailty in Patients Undergoing Cardiac Valve Surgery: Comparison of Frailty Tools

Gabriela Harada et al. Monique Carvalho Andrade Julia Nobrega Brito Caio de Assis Moura Tavares … Flávio Tarasoutchi Pablo Maria Alberto Pomerantzeff Luiz Bortolotto Maria Ignez Zanetti Feltrim

Abstract

Background

There is no consensus among tools for assessing frailty.

Objective

To evaluate the prevalence of frailty according to different tools in patients referred for elective valve cardiac surgery.

Methods

This is a cross-sectional study. All patients were ≥ 18 years of age, clinically stable. The following patients were excluded: those unable to perform the tests because of physical, cognitive, or neurological limitations; those requiring non elective/emergency procedures or hemodynamic instability. During the preoperative cardiology visit, frailty was assessed by the Short Physical Performance Battery (SPPB), the Frailty Deficit Index (FDI), handgrip strength, and gait speed 3m. For the entire analysis, the statistical significance was set at 5%.

Results

Our cohort consisted of 258 subjects. From the total cohort, 201 were ≤ 70 years of age (77.9%), the predominant etiology according to rheumatic disease (50.7% vs 8.8%; p=0.000) with double mitral lesion (24.9% vs 0%; p=0.000). Frailty was present in 32.9% according SPPB, 29.1% with reduced muscular strength. and 8.9% with FDI. Handgrip strength was weaker in elderly patients (26.7 vs 23.6; p=0.051) and gait speed was lower in the younger group, in which 36% were considered frail (36% vs 14%; p=0.002). Variables associated with frailty were age ≥ 70 years, female gender, aortic stenosis, and regurgitation.

Conclusion

Frailty in adult patients who will have elective heart valve surgery is present even in the younger groups, although the older group with comorbidities are more frail. Frailty was more clearly shown by the SPPB than by the FDI and handgrip tests.

  • Cardiac Surgery
  • Frail Elderly
  • Frailty
  • Heart Valve Diseases/surgery
Read Full Article
Creative Commons Attribution (CC BY) Creative Commons license
30/06/2021 DOI: 10.36660/ijcs.20200098
ABC
Original Article

Frailty Among Non-Elderly Patients Undergoing Cardiac Surgery

Camila Bottura et al. Livia Arcêncio Hannah Miranda Araújo Chagas Paulo Roberto Barbosa Evora Alfredo José Rodrigues

Abstract

Background:

Usually viewed as a characteristic of old age, frailty may also occur in non-elderly people, primarily in those suffering from chronic disease. Frailty may increase operative risk.

Objectives:

To determine the prevalence of frailty patients undergoing coronary artery bypass (CABG) and/or heart valve replacement or reconstruction and/or heart valve surgery, as well as the influence of frailty on postoperative outcomes.

Methods:

Our study comprised 100 adults who underwent consecutive elective cardiac operations. Frailty was assessed using the Fried scale. Patients also performed a 6-minute walk test, and we measured maximal inspiratory and expiratory pressures. A p value <0.05 was considered significant.

Results:

Of a cohort of 100 patients, based on the Fried frailty criteria, 17 patients (17%) were considered frail, 70 (70%) pre-frail and only 13 (13%) were non-frail. Among patients with valvular heart disease, 11 (18.6%) were considered frail and 43 (73%) pre-frail. Fifty three percent of the patients considered frail were less than 60 years old (median=48 years old). The differences in frailty phenotype between patients with valvular heart disease and coronary artery disease were not statistically significant (p=0.305). A comparison between non-frail, pre-frail, and frail patients showed no significant difference in the distribution of comorbidities and cardiac functional status, regardless of their cardiac disease. However, hospital mortality was significantly higher in frail patients (29.4%, p=0.026) than in pre-frail patients (8.6%) and non-frail patients (0%).

Conclusions:

Frailty is prevalent even among non-elderly patients undergoing CABG or valvular heart surgery and is associated with higher postoperative hospital mortality.

  • Frailty
  • Heart Valves/surgery
  • Myocardial Revascularization/surgery
  • Postoperative Care/mortality
Read Full Article
Creative Commons Attribution (CC BY) Creative Commons license
23/10/2020 DOI: 10.36660/abc.20190082
Figure 1
ABC
Research Letter

ACE2 Expression and Risk Factors for COVID-19 Severity in Patients with Advanced Age

Caio de Assis Moura Tavares et al. Thiago Junqueira Avelino-Silva Gil Benard Francisco Akira Malta Cardozo … Juliana Ruiz Fernandes Adriana Castello Costa Girardi Wilson Jacob Filho

ACE2, SARS-CoV-2 Infection and Aging

Abnormalities induced by aging in metabolic pathways may partly explain the higher rate of COVID-19 morbidity and mortality in elderly patients. These include those belonging to the renin-angiotensin system (RAS), given the crucial role that this system plays both in viral transmissibility and in the pathogenesis of acute lung injury and its most severe form: acute respiratory distress syndrome (ARDS).

ACE2 is known to act as a receptor for SARS-CoV-2 1 structural protein S (spike), through which the virus gains access to the host cell. This mechanism involves interaction of viral S protein with ACE2 extracellular domain, triggering conformational changes that destabilize the cell membrane, allowing the internalization of SARS-CoV-2 and ACE2, viral replication, and cell-to-cell transmission.,

[…]

  • aging
  • COVID-19
  • Frailty
  • Immunosenescence
  • Multimorbidity
Read Full Article
Creative Commons Attribution (CC BY) Creative Commons license
23/10/2020 DOI: 10.36660/abc.20200487 Views 1
ABC
Editorial

Short Editorial: Frailty among Non-Elderly Patients Undergoing Cardiac Surgery

Iran Castro et al. Hugo Fontana Filho

Frailty is recognized as a geriatric syndrome characterized by an excess of vulnerability to stressors, with a low ability to maintain or recover homeostasis after a destabilizing event. The analysis of frailty is a well-known and studied subject in elderly patients, having a direct relationship with the prognosis and even with measures to be instituted pre-procedure aiming to improve the quality of life and the outcome of the patients.

Despite the original description restricting the term to patients older than 65 years, the syndrome also affects younger patients., Frailty represents more biological and phenotypic aspects than age itself, and precursors of the syndrome appear at a young age.

[…]

  • Frailty
  • Heart Valves/surgery
  • Myocardial Revascularization/surgery
  • Postoperative Care/mortality
Read Full Article
Creative Commons Attribution (CC BY) Creative Commons license
23/10/2020 DOI: 10.36660/abc.20200970 Views 2
Figure 1
IJCS
Editorial

Vascular Aging and Arterial Stiffness in Older Adults

Erika Maria Gonçalves Campana et al. Sayuri Inuzuka

Deaths from cardiovascular disease, according to the WHO, are projected to reach around 14 million by 2030. The global population is aging at an accelerated rate and the prevalence of arterial hypertension (AH) increases with advancing age. Aging is the common denominator in several cardiovascular diseases. Arterial stiffness and increased pulse wave velocity (PWV), as well as central systolic pressure are major predictors of cardiovascular events. ( )

[…]

  • Aged
  • Biomarkers
  • Blood Pressure
  • Cardiovascular Diseases, mortality
  • Frailty
  • Hypertension
  • Pulse Wave Analyses
  • Risk Factors
  • Vascular Stiffness
Read Full Article
Creative Commons Attribution (CC BY) Creative Commons license
31/07/2020 DOI: 10.36660/ijcs.20200132

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Harada G, Andrade MC, Brito JN, Tavares CAM, Tarasoutchi F, Pomerantzeff PMA, Bortolotto L, et al. Prevalence of Frailty in Patients Undergoing Cardiac Valve Surgery: Comparison of Frailty Tools. International Journal of Cardiovascular Sciences 2021;34(5 Supl 1):78-86.

Electronic Document Format (ABNT)

Harada, Gabriela; Andrade, Monique Carvalho; Brito, Julia Nobrega; Tavares, Caio de Assis Moura; Tarasoutchi, Flávio; Pomerantzeff, Pablo Maria Alberto; Bortolotto, Luiz; Feltrim, Maria Ignez Zanetti. Prevalence of Frailty in Patients Undergoing Cardiac Valve Surgery: Comparison of Frailty Tools. International Journal of Cardiovascular Sciences, v. 34, n. 5 Supl 1, p. 78-86, Jun. 2021.

Electronic Document Format (APA)

Harada, G., Andrade, M. C., Brito, J. N., Tavares, C. A. M., Tarasoutchi, F., Pomerantzeff, P. M. A., Bortolotto, L., & Feltrim, M. I. Z. (2021). Prevalence of Frailty in Patients Undergoing Cardiac Valve Surgery: Comparison of Frailty Tools. International Journal of Cardiovascular Sciences, 34(5 Supl 1), 78-86.

Electronic Document Format (ISO)

Harada, Gabriela and Andrade, Monique Carvalho and Brito, Julia Nobrega and Tavares, Caio de Assis Moura and Tarasoutchi, Flávio and Pomerantzeff, Pablo Maria Alberto and Bortolotto, Luiz and Feltrim, Maria Ignez Zanetti. Prevalence of Frailty in Patients Undergoing Cardiac Valve Surgery: Comparison of Frailty Tools. International Journal of Cardiovascular Sciences [online]. 2021, vol. 34, n. 5 Supl 1, [cited 2026-10-14], pp. 78-86. Available from: <https://journals.cardiol.br/en/article/prevalence-of-frailty-in-patients-undergoing-cardiac-valve-surgery-comparison-of-frailty-tools/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Bottura C, Arcêncio L, Chagas HMA, Evora PRB, Rodrigues AJ. Frailty Among Non-Elderly Patients Undergoing Cardiac Surgery. Arquivos Brasileiros de Cardiologia 2020;115(4):604-10.

Electronic Document Format (ABNT)

Bottura, Camila; Arcêncio, Livia; Chagas, Hannah Miranda Araújo; Evora, Paulo Roberto Barbosa; Rodrigues, Alfredo José. Frailty Among Non-Elderly Patients Undergoing Cardiac Surgery. Arquivos Brasileiros de Cardiologia, v. 115, n. 4, p. 604-610, Oct. 2020.

Electronic Document Format (APA)

Bottura, C., Arcêncio, L., Chagas, H. M. A., Evora, P. R. B., & Rodrigues, A. J. (2020). Frailty Among Non-Elderly Patients Undergoing Cardiac Surgery. Arquivos Brasileiros de Cardiologia, 115(4), 604-610.

Electronic Document Format (ISO)

Bottura, Camila and Arcêncio, Livia and Chagas, Hannah Miranda Araújo and Evora, Paulo Roberto Barbosa and Rodrigues, Alfredo José. Frailty Among Non-Elderly Patients Undergoing Cardiac Surgery. Arquivos Brasileiros de Cardiologia [online]. 2020, vol. 115, n. 4, [cited 2026-10-14], pp. 604-610. Available from: <https://journals.cardiol.br/en/article/frailty-among-non-elderly-patients-undergoing-cardiac-surgery/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Tavares CAM, Avelino-Silva TJ, Benard G, Cardozo FAM, Fernandes JR, Girardi ACC, Jacob Filho W, et al. ACE2 Expression and Risk Factors for COVID-19 Severity in Patients with Advanced Age. Arquivos Brasileiros de Cardiologia 2020;115(4):701-7.

Electronic Document Format (ABNT)

Tavares, Caio de Assis Moura; Avelino-Silva, Thiago Junqueira; Benard, Gil; Cardozo, Francisco Akira Malta; Fernandes, Juliana Ruiz; Girardi, Adriana Castello Costa; Jacob Filho, Wilson. ACE2 Expression and Risk Factors for COVID-19 Severity in Patients with Advanced Age. Arquivos Brasileiros de Cardiologia, v. 115, n. 4, p. 701-707, Oct. 2020.

Electronic Document Format (APA)

Tavares, C. A. M., Avelino-Silva, T. J., Benard, G., Cardozo, F. A. M., Fernandes, J. R., Girardi, A. C. C., & Jacob Filho, W. (2020). ACE2 Expression and Risk Factors for COVID-19 Severity in Patients with Advanced Age. Arquivos Brasileiros de Cardiologia, 115(4), 701-707.

Electronic Document Format (ISO)

Tavares, Caio de Assis Moura and Avelino-Silva, Thiago Junqueira and Benard, Gil and Cardozo, Francisco Akira Malta and Fernandes, Juliana Ruiz and Girardi, Adriana Castello Costa and Jacob Filho, Wilson. ACE2 Expression and Risk Factors for COVID-19 Severity in Patients with Advanced Age. Arquivos Brasileiros de Cardiologia [online]. 2020, vol. 115, n. 4, [cited 2026-10-14], pp. 701-707. Available from: <https://journals.cardiol.br/en/article/ace2-expression-and-risk-factors-for-covid-19-severity-in-patients-with-advanced-age/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Castro I, Fontana Filho H. Short Editorial: Frailty among Non-Elderly Patients Undergoing Cardiac Surgery. Arquivos Brasileiros de Cardiologia 2020;115(4):611-2.

Electronic Document Format (ABNT)

Castro, Iran; Fontana Filho, Hugo. Short Editorial: Frailty among Non-Elderly Patients Undergoing Cardiac Surgery. Arquivos Brasileiros de Cardiologia, v. 115, n. 4, p. 611-612, Oct. 2020.

Electronic Document Format (APA)

Castro, I., & Fontana Filho, H. (2020). Short Editorial: Frailty among Non-Elderly Patients Undergoing Cardiac Surgery. Arquivos Brasileiros de Cardiologia, 115(4), 611-612.

Electronic Document Format (ISO)

Castro, Iran and Fontana Filho, Hugo. Short Editorial: Frailty among Non-Elderly Patients Undergoing Cardiac Surgery. Arquivos Brasileiros de Cardiologia [online]. 2020, vol. 115, n. 4, [cited 2026-10-14], pp. 611-612. Available from: <https://journals.cardiol.br/en/article/short-editorial-frailty-among-non-elderly-patients-undergoing-cardiac-surgery/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Campana EMG, Inuzuka S. Vascular Aging and Arterial Stiffness in Older Adults. International Journal of Cardiovascular Sciences 2020;33(4):357-9.

Electronic Document Format (ABNT)

Campana, Erika Maria Gonçalves; Inuzuka, Sayuri. Vascular Aging and Arterial Stiffness in Older Adults. International Journal of Cardiovascular Sciences, v. 33, n. 4, p. 357-359, Jul. 2020.

Electronic Document Format (APA)

Campana, E. M. G., & Inuzuka, S. (2020). Vascular Aging and Arterial Stiffness in Older Adults. International Journal of Cardiovascular Sciences, 33(4), 357-359.

Electronic Document Format (ISO)

Campana, Erika Maria Gonçalves and Inuzuka, Sayuri. Vascular Aging and Arterial Stiffness in Older Adults. International Journal of Cardiovascular Sciences [online]. 2020, vol. 33, n. 4, [cited 2026-10-14], pp. 357-359. Available from: <https://journals.cardiol.br/en/article/vascular-aging-and-arterial-stiffness-in-older-adults/>. ISSN 2359-4802

  • About ABC Family
  • Internal Regulation
  • Editorial Board
  • Brazilian Society of Cardiology (SBC)

Issues

SBC Guidelines

  • Videos
  • Podcasts
  • News