TomographyX-Ray Computed/methods

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Editorial

Role of Computed Tomography in Excluding Acute Coronary Syndrome: is Anatomy the Way?

Chest pain is one of the most common reasons for admission to the emergency room (ER). Although only a small minority of these correspond to an acute coronary syndrome (ACS), the potential severity of a misdiagnosis or a non-diagnosis implies using systematic protocols to confirm or exclude coronary artery disease (CAD) as a cause of symptoms. In recent years, the sequential blood testing of high-sensitive troponin (cTnI-hs) levels has become a safe and effective method in this context and is commonly applied worldwide.^– However, this approach is associated with prolonged times in the ER and is not error-free, as some patients with unstable angina may not be correctly identified.

New approaches using imaging methods to exclude CAD gained relevance and have generated interest from the scientific community. Cardiac CT angiography (CTA), due to its high diagnostic performance, is assumed to be the main candidate to change the status-quo of the current approach based on serial blood testing. It is a simple, fast and robust test with a high negative predictive value – which makes it particularly suitable in ER, where it is essential to quickly and effectively exclude the presence of CAD. The ROMICAT studies were among the first to document the advantages of CTA in this context and to emphasize its additive prognostic value concerning the TIMI risk score (TIMI RS). However, like the vast majority of studies that used CTA in the context of hospital ER, their results mostly apply to low-risk populations.^,

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Research Letter

Three-Dimensional-Printed Heart Prototype for Application in Pediatric Cardiology: An Initial Experiment

Maíra Levorato Basso et al. Alessandra Möbius Gebran Julia Dullius Oliveira Katrin Möbius Gebran … Letícia Carlota Bonatto Maria Cecília Knoll Farah

Introduction

Three-dimensional (3D) prototyping technology is developing rapidly in medicine, and recent studies have shown its important applicability in pediatric cardiology.

Clinicians and surgeons use two-dimensional technologies, such as echocardiography, computed tomography (CT) angiography, and magnetic resonance imaging, to characterize structures and understand complex diseases. Because these images are often projected and extended on a flat screen, they may not represent the actual size of the structures, depth perception, or the proximity between them.

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Role of Computed Tomography in Excluding Acute Coronary Syndrome: is Anatomy the Way?

Three-Dimensional-Printed Heart Prototype for Application in Pediatric Cardiology: An Initial Experiment

Introduction

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