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  2. Keyword: Heart Injuries
Figure 1
ABCHF
Case Report

Post-COVID Tachycardia Syndrome: Could It Be Myocarditis? A Case Report of a Patient Treated with Ivabradine

Davyson Gerhardt de Souza et al. Vanessa do Amaral Tinoco Ligia Cordeiro Matos Faial Humberto Villacorta

Abstract

This report illustrates a case of acute myocarditis in a patient who was recently hospitalized for COVID-19. Myocarditis was suspected based on the presence of tachycardia, the only abnormality present on physical examination, as well as high levels of B-type natriuretic peptide. The diagnosis was confirmed with cardiac magnetic resonance image, which showed the presence of late enhancement, predominantly subepicardial, in the inferolateral and inferior walls of the left ventricle. The patient did not meet any of the criteria for endomyocardial biopsy (progressive heart failure, severe cardiac dysfunction, ventricular arrhythmias, atrioventricular blocks). Therefore, the treatment was focused on heart rate control. Beta-blocker is the first option for rate control, but the patient had a contraindication. Thus, ivabradine, a selective heart rate reducer was used. This drug has been poorly studied in the context of post-COVID-19 syndromes, and the present case suggests a benefit for heart rate control in patients with post-COVID-19 tachycardia syndrome.

  • Heart Injuries
  • Ivabradine
  • Myocarditis
  • Post-Acute COVID-19 Syndrome
  • Tachycardia
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Creative Commons Attribution (CC BY) Creative Commons license
31/12/2023 DOI: 10.36660/abchf.20230066 Views 3
Figure 1
ABC
Original Article

Tramadol Alleviates Myocardial Injury Induced by Acute Hindlimb Ischemia Reperfusion in Rats

Hamed Ashrafzadeh Takhtfooladi et al. Adel Haghighi Khiabanian Asl Mehran Shahzamani Mohammad Ashrafzadeh Takhtfooladi … Amin Allahverdi Mohammadreza Khansari

Abstract

Background:

Organ injury occurs not only during periods of ischemia but also during reperfusion. It is known that ischemia reperfusion (IR) causes both remote organ and local injuries.

Objective:

This study evaluated the effects of tramadol on the heart as a remote organ after acute hindlimb IR.

Methods:

Thirty healthy mature male Wistar rats were allocated randomly into three groups: Group I (sham), Group II (IR), and Group III (IR + tramadol). Ischemia was induced in anesthetized rats by left femoral artery clamping for 3 h, followed by 3 h of reperfusion. Tramadol (20 mg/kg, intravenous) was administered immediately prior to reperfusion. At the end of the reperfusion, animals were euthanized, and hearts were harvested for histological and biochemical examination.

Results:

The levels of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) were higher in Groups I and III than those in Group II (p < 0.05). In comparison with other groups, tissue malondialdehyde (MDA) levels in Group II were significantly increased (p < 0.05), and this increase was prevented by tramadol. Histopathological changes, including microscopic bleeding, edema, neutrophil infiltration, and necrosis, were scored. The total injuryscore in Group III was significantly decreased (p < 0.05) compared with Group II.

Conclusion:

From the histological and biochemical perspectives, treatment with tramadol alleviated the myocardial injuries induced by skeletal muscle IR in this experimental model.

  • Heart Injuries
  • Heart/physiopathology
  • Rats
  • Reperfusion Injury
  • Tramadol/ therapeutic use
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Creative Commons Attribution (CC BY) Creative Commons license
02/06/2015 DOI: 10.5935/abc.20150059 Views 1
Myocardial infarction caused by coronary artery injury after a blunt chest trauma
ABC
Case Report

Myocardial infarction caused by coronary artery injury after a blunt chest trauma

Márcio Silva Miguel Lima et al. Jeane Mike Tsutsui Victor Sarli Issa

We report the case of a 29-year-old man, victim of a car accident, who suffered a severe blunt chest trauma, with evolving congestive heart failure. He had previously had a good overall health status, with no symptoms of cardiovascular disease. At the initial assessment, the electrocardiogram showed Q waves in the precordial leads and the echocardiogram disclosed severe left ventricular dysfunction. Coronary angiogram showed a proximal left anterior descending coronary artery lesion, with anterior wall akinesis on contrast-enhanced ventriculography. A Thallium-201 single photon emission computed tomography (SPECT) showed no viability. He remained on medical treatment with good evolution.

  • Heart Injuries
  • Myocardial Infarction
  • Thoracic Injuries
  • wounds, non penetrating
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Creative Commons Attribution (CC BY) Creative Commons license
13/10/2009 DOI: 10.1590/S0066-782X2009000700013

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Souza DG, Tinoco VA, Faial LCM, Villacorta H. Post-COVID Tachycardia Syndrome: Could It Be Myocarditis? A Case Report of a Patient Treated with Ivabradine. ABC Heart Fail Cardiomyop 2023;3(3):e20230066.

Electronic Document Format (ABNT)

Souza, Davyson Gerhardt de; Tinoco, Vanessa do Amaral; Faial, Ligia Cordeiro Matos; Villacorta, Humberto. Post-COVID Tachycardia Syndrome: Could It Be Myocarditis? A Case Report of a Patient Treated with Ivabradine. ABC Heart Fail Cardiomyop, v. 3, n. 3, e20230066, Dec. 2023.

Electronic Document Format (APA)

Souza, D. G. , Tinoco, V. A., Faial, L. C. M., & Villacorta, H. (2023). Post-COVID Tachycardia Syndrome: Could It Be Myocarditis? A Case Report of a Patient Treated with Ivabradine. ABC Heart Fail Cardiomyop, 3(3), e20230066.

Electronic Document Format (ISO)

Souza, Davyson Gerhardt de and Tinoco, Vanessa do Amaral and Faial, Ligia Cordeiro Matos and Villacorta, Humberto. Post-COVID Tachycardia Syndrome: Could It Be Myocarditis? A Case Report of a Patient Treated with Ivabradine. ABC Heart Fail Cardiomyop [online]. 2023, vol. 3, n. 3, [cited 2026-10-14], e20230066. Available from: <https://journals.cardiol.br/en/article/post-covid-tachycardia-syndrome-could-it-be-myocarditis-a-case-report-of-a-patient-treated-with-ivabradine/>

EndNote RIS

Electronic Document Format (Vancouver)

Takhtfooladi HA, Asl AHK, Shahzamani M, Takhtfooladi MA, Allahverdi A, Khansari M. Tramadol Alleviates Myocardial Injury Induced by Acute Hindlimb Ischemia Reperfusion in Rats. Arquivos Brasileiros de Cardiologia 2015;105(2):151-9.

Electronic Document Format (ABNT)

Takhtfooladi, Hamed Ashrafzadeh; Asl, Adel Haghighi Khiabanian; Shahzamani, Mehran; Takhtfooladi, Mohammad Ashrafzadeh; Allahverdi, Amin; Khansari, Mohammadreza. Tramadol Alleviates Myocardial Injury Induced by Acute Hindlimb Ischemia Reperfusion in Rats. Arquivos Brasileiros de Cardiologia, v. 105, n. 2, p. 151-159, Jun. 2015.

Electronic Document Format (APA)

Takhtfooladi, H. A., Asl, A. H. K., Shahzamani, M., Takhtfooladi, M. A., Allahverdi, A., & Khansari, M. (2015). Tramadol Alleviates Myocardial Injury Induced by Acute Hindlimb Ischemia Reperfusion in Rats. Arquivos Brasileiros de Cardiologia, 105(2), 151-159.

Electronic Document Format (ISO)

Takhtfooladi, Hamed Ashrafzadeh and Asl, Adel Haghighi Khiabanian and Shahzamani, Mehran and Takhtfooladi, Mohammad Ashrafzadeh and Allahverdi, Amin and Khansari, Mohammadreza. Tramadol Alleviates Myocardial Injury Induced by Acute Hindlimb Ischemia Reperfusion in Rats. Arquivos Brasileiros de Cardiologia [online]. 2015, vol. 105, n. 2, [cited 2026-10-14], pp. 151-159. Available from: <https://journals.cardiol.br/en/article/tramadol-alleviates-myocardial-injury-induced-by-acute-hindlimb-ischemia-reperfusion-in-rats/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Lima MSM, Tsutsui JM, Issa VS. Myocardial infarction caused by coronary artery injury after a blunt chest trauma. Arquivos Brasileiros de Cardiologia 2009;93(1):e1-4.

Electronic Document Format (ABNT)

Lima, Márcio Silva Miguel; Tsutsui, Jeane Mike; Issa, Victor Sarli. Myocardial infarction caused by coronary artery injury after a blunt chest trauma. Arquivos Brasileiros de Cardiologia, v. 93, n. 1, p. e1-e4, Oct. 2009.

Electronic Document Format (APA)

Lima, M. S. M., Tsutsui, J. M., & Issa, V. S. (2009). Myocardial infarction caused by coronary artery injury after a blunt chest trauma. Arquivos Brasileiros de Cardiologia, 93(1), e1-e4.

Electronic Document Format (ISO)

Lima, Márcio Silva Miguel and Tsutsui, Jeane Mike and Issa, Victor Sarli. Myocardial infarction caused by coronary artery injury after a blunt chest trauma. Arquivos Brasileiros de Cardiologia [online]. 2009, vol. 93, n. 1, [cited 2026-10-14], pp. e1-e4. Available from: <https://journals.cardiol.br/en/article/myocardial-infarction-caused-by-coronary-artery-injury-after-a-blunt-chest-trauma/>. ISSN 0066-782X

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