Lupus Erythematosus, Systemic

ABCIC

Case Report

Libman-Sacks endocarditis in a male patient with systemic lupus erythematosus

Álvaro Augusto Vedana Filho et al. Vivien Ritchie Bittencourt Thaíssa Antunes Mattar Valente Fernando Silva Botelho Marco Stephan Lofrano Alves

Introduction

Libman-Sacks endocarditis (LSE), also known as marantic or verrucous endocarditis, is a form of non-bacterial thrombotic endocarditis (NBTE) that involves the presence of sterile vegetations in the heart valves. These vegetations may be associated with malignancy, systemic lupus erythematosus (SLE), or antiphospholipid syndrome (APS), and although they are more commonly found in the mitral and aortic valves, other valves may be involved. Diagnosis requires high clinical suspicion when evaluating specific populations.

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Cardiac Imaging for Overlap Connective Tissue Disease Myocarditis

Roberto Muniz Ferreira et al. Hildo da Silva Neto Ana Paula dos Reis Veloso Siciliano Julio Cesar da Silva Borges Blanca Elena Rios Gomes Bica

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Original Article

Early Assessment of Right Ventricular Function in Systemic Lupus Erythematosus Patients using Strain and Strain Rate Imaging

Runlan Luo et al. Hongyan Cui Dongmei Huang Lihua Sun … Shengda Song Mengyao Sun Guangsen Li

Abstract

Background:

Right ventricular function is a crucial factor of the prognosis of systemic lupus erythematosus (SLE).

Objectives:

To evaluate the right ventricular function in SLE patients with different degrees of pulmonary hypertension (PH) by strain and strain rate imaging.

Methods:

A total of 102 SLE patients and 30 healthy volunteers were studied between October 2015 and May 2016. Patients were divided into three groups according to pulmonary artery systolic pressure (PASP) estimated by echocardiography: group control (A); PASP ≤ 30 mmHg (group B, n = 37); PASP 30-50 mmHg (mild PH; group C, n = 34); and PASP ≥ 50 mmHg (moderate-to-severe PH; group D, n = 31). Longitudinal peak systolic strain (ε) and strain rate (SR), including systolic strain rate (SRs), early diastolic strain rate (SRe) and late diastolic strain rate (SRa) were measured in the basal, middle and apical segments of the right ventricular free wall in participants by two-dimensional speckle tracking echocardiography (2D-STE) from the apical four-chamber view. A p < 0.05 was set for statistical significance.

Results:

The parameters of ε, SRs, SRe, and SRa were significantly decreased in groups C and D compared with groups A and B. The ε of each segments was significantly lower in group D than in group C, while there were no differences in SRs, SRe and SRa between groups C and D.

Conclusions:

Strain and strain rate imaging could early detect the right ventricular dysfunction in SLE patients with PH, and provide important value for clinical therapy and prognosis of these patients. (Arq Bras Cardiol. 2018; [online].ahead print, PP.0-0)

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Case Report

Coronary thrombosis as the first complication of antiphospholipid syndrome

Carlos Henrique Miranda et al. Luís Gustavo Gali José Antônio Marin-Neto Paulo Louzada-Júnior Antônio Pazin-Filho

The antiphospholipid syndrome (APS) is an autoimmune thrombophilia, characterized by the presence of plasma antibodies against phospholipids, associated with recurrent episodes of venous and/or arterial thrombosis and gestational morbidity (especially recurrent miscarriage). We report the case of a young female patient diagnosed with systemic lupus erythematosus (SLE) associated with the presence of antiphospholipid antibodies for a long time, presenting with acute myocardial infarction (AMI) due to proximal thrombosis of the anterior descending artery as the first clinical complication of APS.

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Case Report

Association between immunological diseases and their similar clinical manifestations

Alexandre de Matos Soeiro et al. Maria Carolina Feres de Almeida Tarso Augusto Duenhas Accorsi Guilherme Sobreira Spina … Carlos Vicente Serrano Jr Flávio Tarasoutchi

We report on a 30-year-old female patient, with biological mitral valve prosthesis due to symptomatic mitral stenosis and a history of acute myocardial infarction and generalized tonic-clonic seizure episodes, visual hallucinations, cerebral thromboembolic events and, at present, chorea and acute carditis. The patient was diagnosed with active rheumatic fever (RF), systemic lupus erythematosus (SLE) and Antiphospholipid syndrome (APS). The combination of three unusual diagnoses in the same patient makes this a unique case, modifying patient treatment and prognosis.

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Libman-Sacks endocarditis in a male patient with systemic lupus erythematosus

Introduction

Cardiac Imaging for Overlap Connective Tissue Disease Myocarditis

Early Assessment of Right Ventricular Function in Systemic Lupus Erythematosus Patients using Strain and Strain Rate Imaging

Abstract

Background:

Objectives:

Methods:

Results:

Conclusions:

Coronary thrombosis as the first complication of antiphospholipid syndrome

Association between immunological diseases and their similar clinical manifestations

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