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  2. Keyword: Antiphospholipid syndrome
ABCIC
Case Report

A Young Patient with Chest Pain: Going Beyond the Obvious

Sebastian Gallo Bernal et al. Azucena Martínez Juan F Vasquez-Rodriguez Nicolás Isaza … Daniel Isaza Camilo A Calixto Claudia Jaimes

Abstract

Background

Myocardial infarction with nonobstructive coronary arteries (MINOCA) is diagnostically and therapeutically challenging for clinicians, as a large spectrum of causes may result in this clinical condition, multiple entities can mimic it, and there are relatively few evidence-based recommendations for its assessment.

Discussion

Accurate diagnosis of the underlying etiology of MINOCA requires a systematic and dynamic evaluation of the clinical history and work-up of each patient, as well as the use of additional diagnostic tools that allow more in-depth characterization of the cardiac anatomy and coronary function, such as cardiac magnetic resonance imaging, coronary vascular imaging (intravascular ultrasound, optical coherence tomography), and coronary functional assessments. The prognosis of MINOCA highly depends on its underlying cause, and therefore, an accurate diagnosis of its etiology is necessary.

  • Antiphospholipid syndrome
  • Chest Pain
  • Pulmonary embolism
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Creative Commons Attribution (CC BY) Creative Commons license
17/12/2021 DOI: 10.47593/2675-312X/20203304eabc113 Views 1
Biventricular thrombus and endomyocardial fibrosis in antiphospholipid syndrome
ABC
Case Report

Biventricular thrombus and endomyocardial fibrosis in antiphospholipid syndrome

Luiz Flávio Galvão Gonçalves et al. Fernanda Maria Silveira Souto Fernanda Nascimento Faro Joselina Luzia Menezes Oliveira … José Augusto Soares Barreto-Filho Antônio Carlos Sobral Sousa

CASE REPORT

Biventricular thrombus and endomyocardial fibrosis in antiphospholipid syndrome

[…]

  • Antibodies
  • Antiphospholipid
  • Antiphospholipid syndrome
  • Endomyocardial Fibrosis
  • Magnetic Resonance Spectroscopy
  • Thrombosis
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Creative Commons Attribution (CC BY) Creative Commons license
22/11/2012 DOI: 10.1590/S0066-782X2012001400017
Coronary thrombosis as the first complication of antiphospholipid syndrome
ABC
Case Report

Coronary thrombosis as the first complication of antiphospholipid syndrome

Carlos Henrique Miranda et al. Luís Gustavo Gali José Antônio Marin-Neto Paulo Louzada-Júnior Antônio Pazin-Filho

The antiphospholipid syndrome (APS) is an autoimmune thrombophilia, characterized by the presence of plasma antibodies against phospholipids, associated with recurrent episodes of venous and/or arterial thrombosis and gestational morbidity (especially recurrent miscarriage). We report the case of a young female patient diagnosed with systemic lupus erythematosus (SLE) associated with the presence of antiphospholipid antibodies for a long time, presenting with acute myocardial infarction (AMI) due to proximal thrombosis of the anterior descending artery as the first clinical complication of APS.

  • Antiphospholipid syndrome
  • Coronary Thrombosis
  • Lupus Erythematosus, Systemic
  • Myocardial Infarction
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Creative Commons Attribution (CC BY) Creative Commons license
21/06/2012 DOI: 10.1590/S0066-782X2012000400014 Views 1
ABC
Original Article

Echocardiographic Abnormalities and Antiphospholipid Antibodies in Patients with Systemic Lupus Erythematosus

Creso Abreu Falcão et al. Izabel Cristina Alves Wiliam Habib Chahade Ângela Luzia Branco Pinto Duarte Norma Lucena-Silva

OBJECTIVE: Lupus anticoagulant and anticardiolipin antibodies (aCL) have been associated with thrombosis, recurrent abortion, and thrombocytopenia in patients with systemic lupus erythematosus (SLE), but their relationship with cardiac disease is less clear. The purpose of this study was to evaluate the association between antiphospholipid antibodies (aPL) and echocardiographic abnormalities in patients with SLE. METHODS: A total of 70 consecutive patients and 42 control subjects underwent M-mode, 2-dimensional and Doppler echocardiography and tests for lupus anticoagulant, aCL IgG, IgM, and IgA. Lupus anticoagulant was assayed with the dilute Russell viper venom time, and aCL IgG, IgM, and IgA were measured by an enzyme-linked immunosorbent assay (ELISA). RESULTS: Lupus anticoagulant showed a prevalence of 10%. As a whole, aCL had a prevalence of 44.3% and aPL had a prevalence of 50%. Patients with echocardiographic abnormalities had a prevalence of 54.3% and showed a trend towards an association with aCL IgG (P=0.06). The presence of pulmonary hypertension (PH) was significantly associated with aCL IgG (p=0.02). CONCLUSION: aCL IgG was significantly associated with PH and showed a strong trend towards an association with echocardiographic abnormalities taken together. These findings suggest a role for aCL IgG in the development of lupus cardiovascular disease.

  • Antiphospholipid syndrome
  • lupus coagulation inhibitor
  • Lupus Erythematosus
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Creative Commons Attribution (CC BY) Creative Commons license
09/10/2002 DOI: 10.1590/S0066-782X2002001200008 Views 1

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Bernal SG, Martínez A, Vasquez-Rodriguez JF, Isaza N, Isaza D, Calixto CA, Jaimes C, et al. A Young Patient with Chest Pain: Going Beyond the Obvious. Arquivos Brasileiros de Cardiologia Imagem cardiovascular 2021;33(4):1-5.

Electronic Document Format (ABNT)

Bernal, Sebastian Gallo; Martínez, Azucena; Vasquez-Rodriguez, Juan F; Isaza, Nicolás; Isaza, Daniel; Calixto, Camilo A; Jaimes, Claudia. A Young Patient with Chest Pain: Going Beyond the Obvious. Arquivos Brasileiros de Cardiologia Imagem cardiovascular, v. 33, n. 4, p. 1-5, Dec. 2021.

Electronic Document Format (APA)

Bernal, S. G., Martínez, A., Vasquez-Rodriguez, J. F., Isaza, N., Isaza, D., Calixto, C. A., & Jaimes, C. (2021). A Young Patient with Chest Pain: Going Beyond the Obvious. Arquivos Brasileiros de Cardiologia Imagem cardiovascular, 33(4), 1-5.

Electronic Document Format (ISO)

Bernal, Sebastian Gallo and Martínez, Azucena and Vasquez-Rodriguez, Juan F and Isaza, Nicolás and Isaza, Daniel and Calixto, Camilo A and Jaimes, Claudia. A Young Patient with Chest Pain: Going Beyond the Obvious. Arquivos Brasileiros de Cardiologia Imagem cardiovascular [online]. 2021, vol. 33, n. 4, [cited 2026-10-14], pp. 1-5. Available from: <https://journals.cardiol.br/en/article/a-young-patient-with-chest-pain-going-beyond-the-obvious/>. ISSN 2318-8219

EndNote RIS

Electronic Document Format (Vancouver)

Gonçalves LFG, Souto FMS, Faro FN, Oliveira JLM, Barreto-Filho JAS, Sousa ACS. Biventricular thrombus and endomyocardial fibrosis in antiphospholipid syndrome. Arquivos Brasileiros de Cardiologia 2012;99(5):e162-5.

Electronic Document Format (ABNT)

Gonçalves, Luiz Flávio Galvão; Souto, Fernanda Maria Silveira; Faro, Fernanda Nascimento; Oliveira, Joselina Luzia Menezes; Barreto-Filho, José Augusto Soares; Sousa, Antônio Carlos Sobral. Biventricular thrombus and endomyocardial fibrosis in antiphospholipid syndrome. Arquivos Brasileiros de Cardiologia, v. 99, n. 5, p. e162-e165, Nov. 2012.

Electronic Document Format (APA)

Gonçalves, L. F. G., Souto, F. M. S., Faro, F. N., Oliveira, J. L. M., Barreto-Filho, J. A. S., & Sousa, A. C. S. (2012). Biventricular thrombus and endomyocardial fibrosis in antiphospholipid syndrome. Arquivos Brasileiros de Cardiologia, 99(5), e162-e165.

Electronic Document Format (ISO)

Gonçalves, Luiz Flávio Galvão and Souto, Fernanda Maria Silveira and Faro, Fernanda Nascimento and Oliveira, Joselina Luzia Menezes and Barreto-Filho, José Augusto Soares and Sousa, Antônio Carlos Sobral. Biventricular thrombus and endomyocardial fibrosis in antiphospholipid syndrome. Arquivos Brasileiros de Cardiologia [online]. 2012, vol. 99, n. 5, [cited 2026-10-14], pp. e162-e165. Available from: <https://journals.cardiol.br/en/article/biventricular-thrombus-and-endomyocardial-fibrosis-in-antiphospholipid-syndrome/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Miranda CH, Gali LG, Marin-Neto JA, Louzada-Júnior P, Pazin-Filho A. Coronary thrombosis as the first complication of antiphospholipid syndrome. Arquivos Brasileiros de Cardiologia 2012;98(4):e66-9.

Electronic Document Format (ABNT)

Miranda, Carlos Henrique; Gali, Luís Gustavo; Marin-Neto, José Antônio; Louzada-Júnior, Paulo; Pazin-Filho, Antônio. Coronary thrombosis as the first complication of antiphospholipid syndrome. Arquivos Brasileiros de Cardiologia, v. 98, n. 4, p. e66-e69, Jun. 2012.

Electronic Document Format (APA)

Miranda, C. H., Gali, L. G., Marin-Neto, J. A., Louzada-Júnior, P., & Pazin-Filho, A. (2012). Coronary thrombosis as the first complication of antiphospholipid syndrome. Arquivos Brasileiros de Cardiologia, 98(4), e66-e69.

Electronic Document Format (ISO)

Miranda, Carlos Henrique and Gali, Luís Gustavo and Marin-Neto, José Antônio and Louzada-Júnior, Paulo and Pazin-Filho, Antônio. Coronary thrombosis as the first complication of antiphospholipid syndrome. Arquivos Brasileiros de Cardiologia [online]. 2012, vol. 98, n. 4, [cited 2026-10-14], pp. e66-e69. Available from: <https://journals.cardiol.br/en/article/coronary-thrombosis-as-the-first-complication-of-antiphospholipid-syndrome/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Falcão CA, Alves IC, Chahade WH, Duarte LBP, Lucena-Silva N. Echocardiographic Abnormalities and Antiphospholipid Antibodies in Patients with Systemic Lupus Erythematosus. Arquivos Brasileiros de Cardiologia 2002;79(3):285-91.

Electronic Document Format (ABNT)

Falcão, Creso Abreu; Alves, Izabel Cristina; Chahade, Wiliam Habib; Duarte, Ângela Luzia Branco Pinto; Lucena-Silva, Norma. Echocardiographic Abnormalities and Antiphospholipid Antibodies in Patients with Systemic Lupus Erythematosus. Arquivos Brasileiros de Cardiologia, v. 79, n. 3, p. 285-291, Oct. 2002.

Electronic Document Format (APA)

Falcão, C. A., Alves, I. C., Chahade, W. H., Duarte, L. B. P., & Lucena-Silva, N. (2002). Echocardiographic Abnormalities and Antiphospholipid Antibodies in Patients with Systemic Lupus Erythematosus. Arquivos Brasileiros de Cardiologia, 79(3), 285-291.

Electronic Document Format (ISO)

Falcão, Creso Abreu and Alves, Izabel Cristina and Chahade, Wiliam Habib and Duarte, Ângela Luzia Branco Pinto and Lucena-Silva, Norma. Echocardiographic Abnormalities and Antiphospholipid Antibodies in Patients with Systemic Lupus Erythematosus. Arquivos Brasileiros de Cardiologia [online]. 2002, vol. 79, n. 3, [cited 2026-10-14], pp. 285-291. Available from: <https://journals.cardiol.br/en/article/echocardiographic-abnormalities-and-antiphospholipid-antibodies-in-patients-with-systemic-lupus-erythematosus/>. ISSN 0066-782X

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