Cardioprotective Effects of Resistance Training on Obesity

Obesity is characterized as a complex metabolic disorder and is associated with several complications such as cardiovascular diseases, diabetes, renal dysfunction, liver dysfunction and cancer, resulting in impairment of quality of life.

The pathogenesis of obesity has a multifactorial origin and the oxidative stress may play an important role. Studies on animals and cell culture have reported how oxidative stress can contribute to the development of obesity, causing increased preadipocytes proliferation, adipocyte differentiation, and size of mature adipocytes, resulting in increased production of pro-inflammatory cytokines such as tumor necrosis factor alpha (TNF-α).^,

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