Coronary Reperfusion in Acute Myocardial Infarction: Trying the Optimal. Executing the Possible

The infarction-related artery reperfusion strategy began in the 1970s with the intracoronary administration of fibrinolytics.^, This was followed by intravenous administration and mechanical thrombolysis of the “culprit” artery, initially with simple angioplasty and, later, with stenting. All of these procedures had a common goal: to reduce the ischemic/necrotic area, preserve muscle, improve ventricular function and, consequently, survival.

The success of the procedure depends on the time from the onset of symptoms to the moment of the chosen intervention, whether chemical or percutaneous. According to different guidelines, this interval is about 12 hours. The earlier the diagnosis and intervention, the better the clinical outcomes will be.

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