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  2. Keyword: Cardiomiopathy
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ABCHF
Review Article

Conduction Disturbances Leading to Heart Failure – What Clinicians Need to Know

Estêvão Lanna Figueiredo et al. Frank Nunes Fernando Carvalho Neuenschwander Kleisson Antônio Pontes Maia André Assis Lopes do Carmo

Abstract

Recently, pre-excitation syndromes, left bundle branch block (LBBB), and right ventricular pacing have been recognized as causes of cardiomyopathies (CMs). They all have abnormal ventricular activation, that results in what is known as left ventricular (LV) dyssynchrony. These three entities show a common feature of wide QRS and LBBB pattern on the electrocardiogram. The term abnormal conduction-induced CM was, then, proposed. Appropriate diagnosis and treatment of these CMs will possibly improve LV ejection fraction, LV functional capacity and reduce morbidity and mortality. In this article we will briefly review these three clinical conditions, aiming to help clinicians to recognize them, manage and refer patients at risk.

  • Cardiomiopathy
  • Heart Failure
  • Left Bundle Branch Block
  • Left Ventricular Dysfunction
  • Pre-excitation Syndrome
  • Righy Ventricle Pacing
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Creative Commons Attribution (CC BY) Creative Commons license
10/07/2023 DOI: 10.36660/abchf.20230030 Views 1
ABC
Artigo Original

Diastolic dysfunction in diabetic normotensive patients, regardless of the presence of microangiopathy

João Carlos Ferreira Braga et al. Fábio Villaça Guimarães Filho Carlos Roberto Padovani Beatriz B. Matsubara

OBJECTIVE: To assess the Doppler-echocardiographic changes in normotensive patients with type II diabetes mellitus, in the presence or absence of signs of microangiopathy. METHODS: Patients with type II diabetes mellitus were submitted to funduscopy contrasted with fluorescein and dosage of microalbuminuria for diagnose of microangiopathy and divided into two groups: DMII (patients without microangiopathy, n=19) and DM+A (patients with microangiopathy, n=13). All of them were submitted to a Doppler-echocardiography and the results were compared with normotensive patients of same sex and age (group C, n=20), by using the ANOVA, followed by the test of Tukey. In all comparisons the significance level p<0.05 was adopted. RESULTS: There were no differences among the groups regarding the systolic function indicators or left ventricular mass. Differences compatible with diastolic dysfunction in the two groups of diabetic were observed, regardless of the presence of microangiopathy, which showed significantly higher values of the times of isovolumetric relaxation of the left ventricle (TIRLV, ms): (DMII= 97±22.2; DM+A= 107±28.2 and C= 80±10.7; p<0.05), and lower values of the maximum speeds of the wave of fast ventricular filling (E, cm/s): (DMII= 69±17.5; DM+A= 75±19.7 and C= 84±14.5, p<0.05 between DMII and C). There was no difference among the groups concerning the E/A rate. CONCLUSION: Normotensive patients with type II diabetes mellitus and without clinical signs of cardiovascular compromising showed signs of diastolic dysfunction, non-associated to the presence of microangiopathy.

  • Cardiomiopathy
  • Diabetes Mellitus
  • Echocardiogram
  • left ventricle
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Creative Commons Attribution (CC BY) Creative Commons license
28/06/2005 DOI: 10.1590/S0066-782X2005000600006 Views 1

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Figueiredo EL, Nunes F, Neuenschwander FC, Maia KAP, Carmo AAL. Conduction Disturbances Leading to Heart Failure – What Clinicians Need to Know. ABC Heart Fail Cardiomyop 2023;3(1):e20230030.

Electronic Document Format (ABNT)

Figueiredo, Estêvão Lanna; Nunes, Frank; Neuenschwander, Fernando Carvalho; Maia, Kleisson Antônio Pontes; Carmo, André Assis Lopes do. Conduction Disturbances Leading to Heart Failure – What Clinicians Need to Know. ABC Heart Fail Cardiomyop, v. 3, n. 1, e20230030, Jul. 2023.

Electronic Document Format (APA)

Figueiredo, E. L., Nunes, F., Neuenschwander, F. C., Maia, K. A. P., & Carmo, A. A. L. (2023). Conduction Disturbances Leading to Heart Failure – What Clinicians Need to Know. ABC Heart Fail Cardiomyop, 3(1), e20230030.

Electronic Document Format (ISO)

Figueiredo, Estêvão Lanna and Nunes, Frank and Neuenschwander, Fernando Carvalho and Maia, Kleisson Antônio Pontes and Carmo, André Assis Lopes do. Conduction Disturbances Leading to Heart Failure – What Clinicians Need to Know. ABC Heart Fail Cardiomyop [online]. 2023, vol. 3, n. 1, [cited 2026-10-14], e20230030. Available from: <https://journals.cardiol.br/en/article/conduction-disturbances-leading-to-heart-failure-what-clinicians-need-to-know/>

EndNote RIS

Electronic Document Format (Vancouver)

Braga JCF, Guimarães Filho FV, Padovani CR, Matsubara BB. Diastolic dysfunction in diabetic normotensive patients, regardless of the presence of microangiopathy. Arquivos Brasileiros de Cardiologia 2005;84(6):461-6.

Electronic Document Format (ABNT)

Braga, João Carlos Ferreira; Guimarães Filho, Fábio Villaça; Padovani, Carlos Roberto; Matsubara, Beatriz B.. Diastolic dysfunction in diabetic normotensive patients, regardless of the presence of microangiopathy. Arquivos Brasileiros de Cardiologia, v. 84, n. 6, p. 461-466, Jun. 2005.

Electronic Document Format (APA)

Braga, J. C. F., Guimarães Filho, F. V., Padovani, C. R., & Matsubara, B. B. (2005). Diastolic dysfunction in diabetic normotensive patients, regardless of the presence of microangiopathy. Arquivos Brasileiros de Cardiologia, 84(6), 461-466.

Electronic Document Format (ISO)

Braga, João Carlos Ferreira and Guimarães Filho, Fábio Villaça and Padovani, Carlos Roberto and Matsubara, Beatriz B.. Diastolic dysfunction in diabetic normotensive patients, regardless of the presence of microangiopathy. Arquivos Brasileiros de Cardiologia [online]. 2005, vol. 84, n. 6, [cited 2026-10-14], pp. 461-466. Available from: <https://journals.cardiol.br/en/article/diastolic-dysfunction-in-diabetic-normotensive-patients-regardless-of-the-presence-of-microangiopathy/>. ISSN 0066-782X

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