Valdelias Xavier Pereira et al. Tatiana Dias de Carvalho Marcos Antonio Marinovic Junior Alex Rey Norberto … José Maria Soares Júnior Vitor Engrácia Valenti Isabel Cristina Esposito Sorpreso
Abstract
Swyer syndrome is one of the disorders of sexual differentiation. Previous studies have demonstrated increased sympathetic activity with heart rate variability (HRV) analysis with decreasing estradiol levels. One patient presented a pure 46, XY gonadal dysgenesis with female phenotype. Cardiac autonomic modulation was assessed through HRV analysis while at rest. This research analyzed linear and nonlinear indexes. HRV analysis showed reduced parasympathetic and global modulation with an apparent increase in sympathetic tone and a loss of HR fractal dynamics toward correlated behavior, characterized by low entropy and high determinism of time series.