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  2. Keyword: Radial Artery
IJCS
Editorial

From Right to Left Radial Access in Older Patients: Are We Witnessing the Next Procedural Shift?

Sandro Cadaval Gonçalves

The steady rise in percutaneous coronary interventions performed in older patients reflects not only demographic trends but also the growing body of evidence supporting the effectiveness of invasive strategies in this population. Three decades ago, the femoral approach was the undisputed standard. Early reports of transradial access in the early 1990s were met with skepticism, mainly due to concerns about procedural complexity and unfamiliarity with the required technical adjustments. Over time, radial access became the preferred approach. The transition from radial to femoral access offered elderly patients a clear reduction in bleeding and vascular complications. Operators naturally shifted from right femoral to right radial access, remaining on the same side of the patient and often overlooking the more distant left side. As a result, right radial access (RRA) became the default. The choice between RRA and left radial access (LRA) is often driven by habit, operator ergonomics, equipment availability, and catheterization laboratory setup. Emerging evidence suggests this decision warrants closer consideration. In older patients, atherosclerotic and tortuous changes in the subclavian and brachiocephalic arteries are disproportionately more common on the right side. A left radial approach may reduce technical challenges, potentially shortening procedure time and lowering radiation exposure and contrast volume.,

In this issue of the International Journal of Cardiovascular Sciences, Gonçalves et al. shed light on this important topic. In an elegant and technically well-performed systematic review and meta-analysis, including 1,094 patients from three randomized trials and one observational study, the authors provide compelling evidence to reconsider the choice of radial access in elderly patients. While numerous previous reviews have compared LRA and RRA, this study is unique in its exclusive focus on the elderly population. The analysis included studies involving patients aged ≥70 years undergoing diagnostic or therapeutic coronary procedures, comparing RRA and LRA, and reporting at least one of three outcomes: fluoroscopy time, contrast volume, and procedural difficulty.

[…]

  • Aged
  • Coronary Angiography
  • Radial Artery
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Creative Commons Attribution (CC BY) Creative Commons license
27/04/2026 DOI: 10.36660/ijcs.20250195
IJCS
Original Article

Left Versus Right Radial Access in Elderly Patients for Coronary Procedures: A Systematic Review and Meta-Analysis

Anna Loise da Cruz Gonçalves et al. Deivyd Vieira Silva Cavalcante Brenda de Adonai Rodrigues Martins Caroline de Oliveira Fischer Bacca … Júlia Gonçalves Gadelha Suelen Queiroz Gabriel Erzinger Octávio Drummond Guina

Abstract

Background:

Radial artery access is widely used in coronary procedures, but the optimal choice between left (LRA) and right (RRA) radial access remains controversial, especially in older patients.

Objective:

Compare LRA and RRA in patients ≥ 70 years undergoing coronary procedures.

Methods:

This study conducted a systematic review and meta-analysis of observational studies and randomized clinical trials (RCTs), adopting a significance level of 5% for all statistical analyses. We searched PubMed, Embase, and Cochrane Central for studies comparing LRA and RRA in patients aged ≥ 70 years. The main outcomes were fluoroscopy time, contrast volume, and procedure difficulty.

Results:

We included 1,094 patients from 4 studies, of which 3 were RCTs. Among them, 821 (75%) patients underwent the procedure via RRA. The LRA group showed a significantly shorter fluoroscopy time (standard mean difference [MD]: −0.41; 95% confidence interval [CI]: −0.67 to −0.42; p < 0.01; I2 = 80%), and there was a significant reduction in the contrast volume between the groups, favoring LRA (MD: −13.04 milliliters; 95% CI: −18.0 to −8.20; p < 0.01; I2 = 0%). However, there was no significant difference in the perceived difficulty level between the groups (risk ratio [RR]: 1.03; 95% CI: 0.61 to 1.73; p = 0.92; I2 = 0%).

Conclusion:

LRA is associated with a significantly shorter fluoroscopy time, suggesting a greater efficiency in terms of radiation exposure. These findings imply that, while LRA may offer some efficiency benefits, the choice between LRA and RRA should consider other clinical and technical factors, such as operator preference and experience.

  • Aged
  • Cardiology
  • Radial Artery
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Creative Commons Attribution (CC BY) Creative Commons license
09/01/2026 DOI: 10.36660/ijcs.20240246 Views 25
IJCS
Original Article

Option for the Radial versus Femoral Access in Coronary Intervention in Acute Coronary Syndromes: A Risk-Treatment Paradox

Yasmin Falcon Lacerda et al. Nicole Cruz de Sá Jessica Gonzalez Suerdieck Letícia Fonseca … Fernanda Lopes Gabriella Sant'Ana Sodré Mateus dos Santos Viana Marcia Maria Noya Rabelo Luis Claudio Lemos Correia

Abstract

Background:

In coronary procedures, although the radial approach protects patients from hemorrhagic complications, it is technically more complex than the femoral approach.

Objectives:

To test the hypothesis that the radial approach is the procedure of choice in ACS patients due to the high risk of bleeding; and to identify independent predictors of the choice for radial access.

Methods:

Patients admitted for ACS who underwent invasive coronary procedure were included. We registered the type of access (femoral or radial) chosen by the physician for the first angiography; the investigators did not interfere with this choosing process. Student’s t-test was used for comparisons between the CRUSADE and ACUITY scores. Predictors of radial access were compared between the groups. Statistical significance was defined by p < 0,05.

Results: Radial access was chosen in 67% of 347 consecutive patients. Patients who underwent radial approach had lower risk of bleeding determined by CRUSADE (30 ± 14 vs. 37 ± 15; p < 0.001) as compared with femoral access. In multivariate analysis, four variables were identified as independent predictors negatively associated with radial access – age (OR = 0.98; 95%CI = 0.96 – 0.99), creatinine (OR = 0.54; 95%CI = 0.3 – 0.98), signs of left ventricular failure (OR = 0.45; 95% CI = 0.22 – 0.92) and previous CABG (OR = 0.022; 95%CI = 0.003 – 0.166).

Conclusion:

The propensity to choose radial over femoral access in coronary intervention was not primarily influenced by patients’ bleeding risk. Predictors of this decision, identified in the study, indicated less complex patients, suggesting that the difficulty in performing the technique was a stronger determinant than its potential antihemorrhagic effect. (Int J Cardiovasc Sci. 2018; [online].ahead print, PP.0-0)

  • Angioplasty
  • Catheterism
  • Coronary Artery Disease
  • Femoral Artery
  • Percutaneous Coronary Intervention
  • Radial Artery
  • Stents
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Creative Commons Attribution (CC BY) Creative Commons license
27/08/2018 DOI: 10.5935/2359-4802.20180066
ABC
Original Article

Transradial approach for coronary interventions

José Carlos Brito et al. Antônio Azevedo Júnior Adriano Oliveira Roberto Von Sohsten … Ademar Santos Filho Heitor Carvalho

OBJECTIVE: To assess the feasibility and safety of coronary interventions performed through the radial artery. METHODS: We studied 103 patients with ages from 38 to 86 years (57±8.7), 90 (87%) males, and: radial pulse with a good amplitude, presence of ulnar pulse, a good collateral flow through the palmar arch assessed with the Allen’s test. RESULTS: The vascular approach was obtained in 97 (94%) patients, 88 (91%) treated electively and 9 (9%) during acute myocardial infarction, for primary angioplasty; 56 (64%) unstable angina; 22 (25%) stable angina; 10 (11%) were asymptomatic, 6 referred for recanalization of chronic occlusion and 4 silent ischemia in the first week after acute myocardial infarction. We approached 107 arteries: anterior descending artery, 49 (46%); right coronary artery, 27 (25%); circumflex artery, 25 (23%); diagonal artery, 6 (6%); and 2 saphenous vein bypass grafts. We treated 129 lesions: 80 (62%) B2 type; 23 (18%) B1 type; 17 (13%) C type; and 9 (7%). A type. There were 70 stents , and 59 balloon angioplasties performed. Thirty-two (33%) patients used GP IIb/IIIa inhibitors. The mean duration of the elective procedure was 42.3±12.8 min. Success, correct stent deployment and residual lesion <20%, was reached in 100% of the lesions treated with stent implantation; arterial dilation with residual lesion <50% was obtained in 96% of the lesions treated with transluminal coronary angioplasty (TCA). Complications, were: 1 (1.0%) non-Q-wave acute myocardial infarction; 2 (2%) hematomas in the forearm; and 2 losses of radial pulse. CONCLUSION: Radial artery aproach is practical and safe for percutaneous coronary interventions there was a low incidence of complications.

  • percutaneous interventions
  • Radial Artery
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Creative Commons Attribution (CC BY) Creative Commons license
08/01/2002 DOI: 10.1590/S0066-782X2001000500003

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Gonçalves SC. From Right to Left Radial Access in Older Patients: Are We Witnessing the Next Procedural Shift?. International Journal of Cardiovascular Sciences 2026;39:e20250195.

Electronic Document Format (ABNT)

Gonçalves, Sandro Cadaval. From Right to Left Radial Access in Older Patients: Are We Witnessing the Next Procedural Shift?. International Journal of Cardiovascular Sciences, v. 39, e20250195, abr. 2026.

Electronic Document Format (APA)

Gonçalves, S. C. (2026). From Right to Left Radial Access in Older Patients: Are We Witnessing the Next Procedural Shift?. International Journal of Cardiovascular Sciences, 39, e20250195.

Electronic Document Format (ISO)

Gonçalves, Sandro Cadaval. From Right to Left Radial Access in Older Patients: Are We Witnessing the Next Procedural Shift?. International Journal of Cardiovascular Sciences [online]. 2026, vol. 39, [cited 2026-09-30], e20250195. Available from: <https://journals.cardiol.br/article/from-right-to-left-radial-access-in-older-patients-are-we-witnessing-the-next-procedural-shift-2/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Gonçalves ALC, Cavalcante DVS, Martins BAR, Bacca COF, Gadelha JG, Queiroz S, Erzinger G, et al. Left Versus Right Radial Access in Elderly Patients for Coronary Procedures: A Systematic Review and Meta-Analysis. International Journal of Cardiovascular Sciences 2026;38:e20240246.

Electronic Document Format (ABNT)

Gonçalves, Anna Loise da Cruz; Cavalcante, Deivyd Vieira Silva; Martins, Brenda de Adonai Rodrigues; Bacca, Caroline de Oliveira Fischer; Gadelha, Júlia Gonçalves; Queiroz, Suelen; Erzinger, Gabriel; Guina, Octávio Drummond. Left Versus Right Radial Access in Elderly Patients for Coronary Procedures: A Systematic Review and Meta-Analysis. International Journal of Cardiovascular Sciences, v. 38, e20240246, jan. 2026.

Electronic Document Format (APA)

Gonçalves, A. L. C., Cavalcante, D. V. S., Martins, B. A. R., Bacca, C. O. F., Gadelha, J. G., Queiroz, S., Erzinger, G., & Guina, O. D. (2026). Left Versus Right Radial Access in Elderly Patients for Coronary Procedures: A Systematic Review and Meta-Analysis. International Journal of Cardiovascular Sciences, 38, e20240246.

Electronic Document Format (ISO)

Gonçalves, Anna Loise da Cruz and Cavalcante, Deivyd Vieira Silva and Martins, Brenda de Adonai Rodrigues and Bacca, Caroline de Oliveira Fischer and Gadelha, Júlia Gonçalves and Queiroz, Suelen and Erzinger, Gabriel and Guina, Octávio Drummond. Left Versus Right Radial Access in Elderly Patients for Coronary Procedures: A Systematic Review and Meta-Analysis. International Journal of Cardiovascular Sciences [online]. 2026, vol. 38, [cited 2026-09-30], e20240246. Available from: <https://journals.cardiol.br/article/left-versus-right-radial-access-in-elderly-patients-for-coronary-procedures-a-systematic-review-and-meta-analysis-2/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Lacerda YF, Sá NC, Suerdieck JG, Fonseca L, Lopes F, Sodré GS, Viana MS, et al. Option for the Radial versus Femoral Access in Coronary Intervention in Acute Coronary Syndromes: A Risk-Treatment Paradox. International Journal of Cardiovascular Sciences 2018;31(6):562-8.

Electronic Document Format (ABNT)

Lacerda, Yasmin Falcon; Sá, Nicole Cruz de; Suerdieck, Jessica Gonzalez; Fonseca, Letícia; Lopes, Fernanda; Sodré, Gabriella Sant’Ana; Viana, Mateus dos Santos; Rabelo, Marcia Maria Noya; Correia, Luis Claudio Lemos. Option for the Radial versus Femoral Access in Coronary Intervention in Acute Coronary Syndromes: A Risk-Treatment Paradox. International Journal of Cardiovascular Sciences, v. 31, n. 6, p. 562-568, ago. 2018.

Electronic Document Format (APA)

Lacerda, Y. F., Sá, N. C. , Suerdieck, J. G., Fonseca, L., Lopes, F., Sodré, G. S., Viana, M. S., Rabelo, M. M. N., & Correia, L. C. L. (2018). Option for the Radial versus Femoral Access in Coronary Intervention in Acute Coronary Syndromes: A Risk-Treatment Paradox. International Journal of Cardiovascular Sciences, 31(6), 562-568.

Electronic Document Format (ISO)

Lacerda, Yasmin Falcon and Sá, Nicole Cruz de and Suerdieck, Jessica Gonzalez and Fonseca, Letícia and Lopes, Fernanda and Sodré, Gabriella Sant’Ana and Viana, Mateus dos Santos and Rabelo, Marcia Maria Noya and Correia, Luis Claudio Lemos. Option for the Radial versus Femoral Access in Coronary Intervention in Acute Coronary Syndromes: A Risk-Treatment Paradox. International Journal of Cardiovascular Sciences [online]. 2018, vol. 31, n. 6, [cited 2026-09-30], pp. 562-568. Available from: <https://journals.cardiol.br/article/option-for-the-radial-versus-femoral-access-in-coronary-intervention-in-acute-coronary-syndromes-a-risk-treatment-paradox-2/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Brito JC, Azevedo Júnior A, Oliveira A, Sohsten RV, Santos Filho A, Carvalho H. Transradial approach for coronary interventions. Arquivos Brasileiros de Cardiologia 2002;76(5):374-8.

Electronic Document Format (ABNT)

Brito, José Carlos; Azevedo Júnior, Antônio; Oliveira, Adriano; Sohsten, Roberto Von; Santos Filho, Ademar; Carvalho, Heitor. Transradial approach for coronary interventions. Arquivos Brasileiros de Cardiologia, v. 76, n. 5, p. 374-378, jan. 2002.

Electronic Document Format (APA)

Brito, J. C., Azevedo Júnior, A., Oliveira, A., Sohsten, R. V., Santos Filho, A., & Carvalho, H. (2002). Transradial approach for coronary interventions. Arquivos Brasileiros de Cardiologia, 76(5), 374-378.

Electronic Document Format (ISO)

Brito, José Carlos and Azevedo Júnior, Antônio and Oliveira, Adriano and Sohsten, Roberto Von and Santos Filho, Ademar and Carvalho, Heitor. Transradial approach for coronary interventions. Arquivos Brasileiros de Cardiologia [online]. 2002, vol. 76, n. 5, [cited 2026-09-30], pp. 374-378. Available from: <https://journals.cardiol.br/article/transradial-approach-for-coronary-interventions-2/>. ISSN 0066-782X

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