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  2. Palavra-chave: Morbidity and Mortality
IJCS
Original Article

Pharmaceutical Care in Primary Care: an Experience with Hypertensive Patients in the North of Brazil

Ilvia Silva Gomes et al. Elaine Menezes Rossi Samara Jamile Mendes Brigitte Rieckmann Martins dos Santos Wilson Sabino

Abstract

Background:

Uncontrolled blood pressure has been associated with poor adherence to drug treatment.

Objectives:

To assess blood pressure control in hypertensive patients attending primary health centers after implementation of a pharmaceutical follow-up program in a city of the north of Brazil.

Methods:

Observational, cross sectional, descriptive study with 163 hypertensive patients attending public primary health care centers – one located on the riverside and one in the urban area of the city of Santarem, western Pará, Brazil. Adherence to the anti-hypertensive treatment was assessed using the eight-item Morisky test. Pharmacotherapy follow-up (Dader method) of patients with uncontrolled hypertension and non-adherent to anti-hypertensive treatment was performed. Results of the normality test showed that the data did not follow a normal distribution. Continuous variables were then compared using the Wilcoxon signed-rank test, and categorical variables by the likelihood ratio and the McNemar tests. Statistical significance was set at 5%.

Results:

Of the total sample, 94.5% were not adherent to anti-hypertensive drug therapy and 77.2% had uncontrolled hypertension. Adherence rate was higher in men than women (p=0.006). Pharmacotherapy follow-up improved blood pressure levels, particularly systolic blood pressure (p<0.001).

Conclusion:

An individualized pharmacotherapeutic follow-up, considering regional and cultural specificities, can contribute to the treatment of hypertensin in the primary care.

  • Epidemiology
  • Hypertension
  • medication adherence
  • Morbidity and Mortality
  • Patient Care Management
  • Risk Factors
  • Urban Area
Ler artigo completo
Creative Commons Attribution (CC BY) Creative Commons license
25/02/2022 DOI: 10.36660/ijcs.20200257 Visualizações 2
IJCS
Review Article

Reperfusion Strategies in Acute Myocardial Infarction: State of the Art

Fernando Oswaldo Dias Rangel

Abstract

ST elevation myocardial infarction (STEMI) is a highly prevalent condition worldwide. Reperfusion therapy is strongly associated with the prognosis of STEMI and must be performed with a high standard of quality and without delay. A systematic review of different reperfusion strategies for STEMI was conducted, including randomized controlled trials that included major cardiovascular events (MACE), and systematic reviews in the last 5 years through the PRISMA ( Preferred Reporting Items for Systematic Reviews and Meta-Analysis) methodology. The research was done in the PubMed and Cochrane Central Register of Controlled Trials databases, in addition to a few manual searches. After the exclusion criteria were applied, 90 articles were selected for this review. Despite the reestablishment of IRA patency in PCI for STEMI, microvascular lesions occur in a significant proportion of these patients, which can compromise ventricular function and clinical course. Several therapeutic strategies – intracoronary administration of nicorandil, nitrates, melatonin, antioxidant drugs (quercetin, glutathione), anti-inflammatory substances (tocilizumab [an inhibitor of interleukin 6], inclacumab, P-selectin inhibitor), immunosuppressants (cyclosporine), erythropoietin and ischemic pre- and post-conditioning and stem cell therapy – have been tested to reduce reperfusion injury, ventricular remodeling and serious cardiovascular events, with heterogeneous results: These therapies need confirmation in larger studies to be implemented in clinical practice

  • Acute Myocardial Infarction/therapy
  • Morbidity and Mortality
  • Myocardial Reperfusion
  • Myocardial Stunning
  • ventricular remodeling
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Creative Commons Attribution (CC BY) Creative Commons license
09/06/2021 DOI: 10.36660/ijcs.20200226 Visualizações 2
IJCS
Case Report

The Association between Covid-19 and ST Elevation Myocardial Infarction: Variable Clinical Presentations on a Case Report Series

Vinicius Esteves et al. Cleverson Neves Zukowski Fabio Augusto de Luca Italo Bruno dos Santos Sousa … Bruno Santana Bandeira Angelina Camiletti Guilherme Arruda André Feldman Olga Ferreira de Souza

Introduction

The current global pandemic caused by the new coronavirus (COVID-19) already reaches 185 countries with approximately 3 million infected people and more than 200 thousand deaths. , With continental dimensions and an elevated socioeconomic disparity, Brazil, by the beginning of May, presents with increasing infection rates and mortality close to 8%. The numbers may be higher considering the lack of adequate testing of the population and healthcare professionals.

According to the World Health Organization (WHO), cardiovascular diseases represent the leading cause of deaths around the world. . Recent reports confirmed that patients with cardiovascular comorbidities are at a higher risk to develop the most severe form of the COVID-19. – The association between these two pathologies can lead to high morbidity and mortality rates and has been the object of continuous efforts by the medical community. In this sense the management of Acute Coronary Syndrome (ACS) has undergone changes in both diagnosis and treatment since the beginning of the pandemic. – Another aggravating factor regarding the approach of ACS during this period is the multiple clinical presentations and differential diagnosis associated with COVID-19, such as myopericarditis, pulmonary embolism and arrhythmia. –

[…]

  • acute coronary syndrome
  • chest pain
  • Coronavírus
  • COVID-19
  • Diabetes mellitus
  • Hypertension
  • Morbidity and Mortality
  • Pandemics
  • Severe Acute Respiratory Syndrome
  • ST Elevation Myocardial Infarction
Ler artigo completo
Creative Commons Attribution (CC BY) Creative Commons license
31/07/2020 DOI: 10.36660/ijcs.20200122 Visualizações 1

Como citar este artigo

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Gomes IS, Rossi EM, Mendes SJ, Santos BRM, Sabino W. Pharmaceutical Care in Primary Care: an Experience with Hypertensive Patients in the North of Brazil. International Journal of Cardiovascular Sciences 2022;35(3):318-26.

Formato de Documento Eletrônico (ABNT)

Gomes, Ilvia Silva; Rossi, Elaine Menezes; Mendes, Samara Jamile; Santos, Brigitte Rieckmann Martins dos; Sabino, Wilson. Pharmaceutical Care in Primary Care: an Experience with Hypertensive Patients in the North of Brazil. International Journal of Cardiovascular Sciences, v. 35, n. 3, p. 318-326, fev. 2022.

Formato de Documento Eletrônico (APA)

Gomes, I. S., Rossi, E. M., Mendes, S. J., Santos, B. R. M. , & Sabino, W. (2022). Pharmaceutical Care in Primary Care: an Experience with Hypertensive Patients in the North of Brazil. International Journal of Cardiovascular Sciences, 35(3), 318-326.

Formato de Documento Eletrônico (ISO)

Gomes, Ilvia Silva and Rossi, Elaine Menezes and Mendes, Samara Jamile and Santos, Brigitte Rieckmann Martins dos and Sabino, Wilson. Pharmaceutical Care in Primary Care: an Experience with Hypertensive Patients in the North of Brazil. International Journal of Cardiovascular Sciences [online]. 2022, vol. 35, n. 3, [citado 2026-10-14], pp. 318-326. Disponível em: <https://journals.cardiol.br/article/pharmaceutical-care-in-primary-care-an-experience-with-hypertensive-patients-in-the-north-of-brazil-2/>. ISSN 2359-4802

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Rangel FOD. Reperfusion Strategies in Acute Myocardial Infarction: State of the Art. International Journal of Cardiovascular Sciences 2021;35(1):113-22.

Formato de Documento Eletrônico (ABNT)

Rangel, Fernando Oswaldo Dias. Reperfusion Strategies in Acute Myocardial Infarction: State of the Art. International Journal of Cardiovascular Sciences, v. 35, n. 1, p. 113-122, jun. 2021.

Formato de Documento Eletrônico (APA)

Rangel, F. O. D. (2021). Reperfusion Strategies in Acute Myocardial Infarction: State of the Art. International Journal of Cardiovascular Sciences, 35(1), 113-122.

Formato de Documento Eletrônico (ISO)

Rangel, Fernando Oswaldo Dias. Reperfusion Strategies in Acute Myocardial Infarction: State of the Art. International Journal of Cardiovascular Sciences [online]. 2021, vol. 35, n. 1, [citado 2026-10-14], pp. 113-122. Disponível em: <https://journals.cardiol.br/article/reperfusion-strategies-in-acute-myocardial-infarction-state-of-the-art-2/>. ISSN 2359-4802

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Esteves V, Zukowski CN, Luca FA, Sousa IBS, Bandeira BS, Camiletti A, Arruda G, et al. The Association between Covid-19 and ST Elevation Myocardial Infarction: Variable Clinical Presentations on a Case Report Series. International Journal of Cardiovascular Sciences 2020;33(4):429-35.

Formato de Documento Eletrônico (ABNT)

Esteves, Vinicius; Zukowski, Cleverson Neves; Luca, Fabio Augusto de; Sousa, Italo Bruno dos Santos; Bandeira, Bruno Santana; Camiletti, Angelina; Arruda, Guilherme; Feldman, André; Souza, Olga Ferreira de. The Association between Covid-19 and ST Elevation Myocardial Infarction: Variable Clinical Presentations on a Case Report Series. International Journal of Cardiovascular Sciences, v. 33, n. 4, p. 429-435, jul. 2020.

Formato de Documento Eletrônico (APA)

Esteves, V., Zukowski, C. N., Luca, F. A. , Sousa, I. B. S., Bandeira, B. S., Camiletti, A., Arruda, G., Feldman, A., & Souza, O. F. (2020). The Association between Covid-19 and ST Elevation Myocardial Infarction: Variable Clinical Presentations on a Case Report Series. International Journal of Cardiovascular Sciences, 33(4), 429-435.

Formato de Documento Eletrônico (ISO)

Esteves, Vinicius and Zukowski, Cleverson Neves and Luca, Fabio Augusto de and Sousa, Italo Bruno dos Santos and Bandeira, Bruno Santana and Camiletti, Angelina and Arruda, Guilherme and Feldman, André and Souza, Olga Ferreira de. The Association between Covid-19 and ST Elevation Myocardial Infarction: Variable Clinical Presentations on a Case Report Series. International Journal of Cardiovascular Sciences [online]. 2020, vol. 33, n. 4, [citado 2026-10-14], pp. 429-435. Disponível em: <https://journals.cardiol.br/article/the-association-between-covid-19-and-st-elevation-myocardial-infarction-variable-clinical-presentations-on-a-case-report-series-2/>. ISSN 2359-4802

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