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  1. Início
  2. Palavra-chave: Heart Ventricles
IJCS
Editorial

The "Right" Side of Myocardial Infarction: Sinister Outcomes?

Monica Verdoia

Right ventricular myocardial infarction (RVI) is rarely an isolated event; rather, it generally complicates 10% to 50% of cases of acute inferior ST-segment elevation myocardial infarction (STEMI)., Proximal right coronary artery occlusion, impairing right ventricular (RV) branch flow, is most frequently the culprit vessel, although it depends on coronary tree anatomy.

Previous studies underlined that RVI is often unrecognized, since RV ischemic dysfunction is generally transient, due to the different composition and higher resistance to hypoxia of the RV wall. In addition, the diagnostic criteria for RVI, which are mainly based on electrocardiogram (), can lead to underestimation, unless RV involvement becomes clinically manifest with hemodynamic complications. In fact, acute RV dysfunction can lead to reduced output, insufficient left heart filling, and cardiogenic shock, despite preserved left contractility. Moreover, intrapericardial ventricular interaction can translate into an abrupt RV dilation and further compression of the left chambers.

[…]

  • Heart Ventricles
  • Myocardial Infarction
  • Percutaneous Coronary Intervention
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Creative Commons Attribution (CC BY) Creative Commons license
13/03/2026 DOI: 10.36660/ijcs.20250249
IJCS
Case Report

Transcatheter Correction of Aortic-Right Ventricular Shunt Following Aortic Valve Replacement: A Case Report

Adnaldo da Silveira Maia et al. Mauro Henrique Batista Camacho Andresa Fernandes Perego Dayara Hoffmann Mayer José Honório Palma da Fonseca

Abstract

We describe the first case in the literature of transcatheter correction of aortic-right ventricular (Ao-RV) shunt after aortic valve replacement (AVR) with an Intuity® prosthesis (Edwards Lifesciences). A 79-year-old patient with a history of coronary artery bypass grafting and aortic regurgitation underwent AVR using a rapid-release 25-mm Intuity® prosthesis. After 45 days, he presented with severe heart failure, and an Ao-RV shunt was identified on transthoracic echocardiography. Given his history of previous cardiac surgeries, percutaneous correction was attempted. Initially, an attempt was made to catheterize the defect via the transapical approach, which was unsuccessful. The right femoral artery was punctured, and the shunt was catheterized via the aorta, with the implantation of a MemoPart ventricular septal defects (VSD) occluder, resulting in a significant reduction of the shunt. The patient was then transferred to the intensive care unit. However, there was no satisfactory clinical improvement, and transthoracic echocardiography revealed persistent Ao-RV shunt. Therefore, the surgical team opted for a new approach through the femoral artery and a second MemoPart VSD occluder was implanted. A transesophageal echocardiogram showed no leak, and the patient progressed satisfactorily and was discharged from the hospital. Shunts after AVR are rare. In these conditions, percutaneous management is a safe and feasible technical option. This is the first case reported in the literature of this type of complication after Intuity prosthesis implantation.

  • Aorta
  • Heart Ventricles
  • Transcatheter Aortic Valve Replacement
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Creative Commons Attribution (CC BY) Creative Commons license
09/01/2026 DOI: 10.36660/ijcs.20250060
IJCS
Original Article

Effects of Exercise Training on Left Ventricular Diastolic Function Markers in Patients with Obstructive Sleep Apnea: A Randomized Study

Bruno G. Durante et al. Rosyvaldo Ferreira-Silva Thiago T. Goya Marta F. Lima … Ana Clara T. Rodrigues Luciano F. Drager Camila P. Jordão Amanda G. Rodrigues Maria Janieire de Nazare N. Alves Geraldo Lorenzi-Filho Carlos E. Negrão Linda M. Ueno-Pardi

Abstract

Background

Exercise training (ET) is an adjunctive treatment for obstructive sleep apnea (OSA) and its consequences. However, the effects of exercise on heart remodeling are unknown in the population with OSA.

Objective

We investigated the effect of ET on markers of diastolic function, sleep parameters, and functional capacity in patients with OSA.

Methods

Sedentary patients with OSA (apnea-hypopnea index, AHI ≥15 events/hr) were randomly assigned to untrained (n=18) and trained (n=20) strategies. Polysomnography, cardiopulmonary exercise test, and echocardiography were evaluated at the beginning and end of the study. ET consisted of 3 weekly sessions of aerobic exercise, resistance exercises, and flexibility training (72 sessions, completed in 11.65±0.86 months). A two-way analysis of variance (ANOVA) was used, followed by Tukey’s post-hoc test. The level of statistical significance was set at p<0.05 for all analyses.

Result

Thirty-eight patients were included (AHI:45±29 events/hr, age:52±7 y, body mass index: 30±4 kg/m2). They had similar baseline parameters. ET caused a significant change in OSA severity (AHI:4.5±18 versus -5.7±13 events/hr; arousal index:1.5±8 versus -6.1±13 events/hr, in untrained and trained groups respectively, p<0.05). The trained patients had an increase in functional capacity after intervention. ET improved isovolumetric relaxation time (IVRT, untrained=6.5±17.3 versus trained=-5.1±17.1 msec, p<0.05). There was a significant correlation between changes in IVRT and arousal index in the trained group (r =-0.54, p<0.05). No difference occurred in the other diastolic function parameters evaluated.

Conclusion

ET promotes modest but significant improvement in AHI, functional capacity, and cardiac IVRT, a validated parameter of diastolic function.

  • exercise
  • Heart Ventricles
  • Obstructive
  • Sleep Apnea
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Creative Commons Attribution (CC BY) Creative Commons license
22/06/2022 DOI: 10.36660/ijcs.20210146 Visualizações 1

Como citar este artigo

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Verdoia M. The “Right” Side of Myocardial Infarction: Sinister Outcomes?. International Journal of Cardiovascular Sciences 2026;39:e20250249.

Formato de Documento Eletrônico (ABNT)

Verdoia, Monica. The “Right” Side of Myocardial Infarction: Sinister Outcomes?. International Journal of Cardiovascular Sciences, v. 39, e20250249, mar. 2026.

Formato de Documento Eletrônico (APA)

Verdoia, M. (2026). The “Right” Side of Myocardial Infarction: Sinister Outcomes?. International Journal of Cardiovascular Sciences, 39, e20250249.

Formato de Documento Eletrônico (ISO)

Verdoia, Monica. The “Right” Side of Myocardial Infarction: Sinister Outcomes?. International Journal of Cardiovascular Sciences [online]. 2026, vol. 39, [citado 2026-10-14], e20250249. Disponível em: <https://journals.cardiol.br/article/the-right-side-of-myocardial-infarction-sinister-outcomes-2/>. ISSN 2359-4802

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Maia AS, Camacho MHB, Perego AF, Mayer DH, Fonseca JHP. Transcatheter Correction of Aortic-Right Ventricular Shunt Following Aortic Valve Replacement: A Case Report. International Journal of Cardiovascular Sciences 2026;38:e20250060.

Formato de Documento Eletrônico (ABNT)

Maia, Adnaldo da Silveira; Camacho, Mauro Henrique Batista; Perego, Andresa Fernandes; Mayer, Dayara Hoffmann; Fonseca, José Honório Palma da. Transcatheter Correction of Aortic-Right Ventricular Shunt Following Aortic Valve Replacement: A Case Report. International Journal of Cardiovascular Sciences, v. 38, e20250060, jan. 2026.

Formato de Documento Eletrônico (APA)

Maia, A. S., Camacho, M. H. B., Perego, A. F., Mayer, D. H., & Fonseca, J. H. P. (2026). Transcatheter Correction of Aortic-Right Ventricular Shunt Following Aortic Valve Replacement: A Case Report. International Journal of Cardiovascular Sciences, 38, e20250060.

Formato de Documento Eletrônico (ISO)

Maia, Adnaldo da Silveira and Camacho, Mauro Henrique Batista and Perego, Andresa Fernandes and Mayer, Dayara Hoffmann and Fonseca, José Honório Palma da. Transcatheter Correction of Aortic-Right Ventricular Shunt Following Aortic Valve Replacement: A Case Report. International Journal of Cardiovascular Sciences [online]. 2026, vol. 38, [citado 2026-10-14], e20250060. Disponível em: <https://journals.cardiol.br/article/transcatheter-correction-of-aortic-right-ventricular-shunt-following-aortic-valve-replacement-a-case-report-2/>. ISSN 2359-4802

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Durante BG, Ferreira-Silva R, Goya TT, Lima MF, Rodrigues ACT, Drager LF, Jordão CP, et al. Effects of Exercise Training on Left Ventricular Diastolic Function Markers in Patients with Obstructive Sleep Apnea: A Randomized Study. International Journal of Cardiovascular Sciences 2022;35(5):646-5.

Formato de Documento Eletrônico (ABNT)

Durante, Bruno G.; Ferreira-Silva, Rosyvaldo; Goya, Thiago T.; Lima, Marta F.; Rodrigues, Ana Clara T.; Drager, Luciano F.; Jordão, Camila P.; Rodrigues, Amanda G.; Alves, Maria Janieire de Nazare N.; Lorenzi-Filho, Geraldo; Negrão, Carlos E.; Ueno-Pardi, Linda M.. Effects of Exercise Training on Left Ventricular Diastolic Function Markers in Patients with Obstructive Sleep Apnea: A Randomized Study. International Journal of Cardiovascular Sciences, v. 35, n. 5, p. 646-656, jun. 2022.

Formato de Documento Eletrônico (APA)

Durante, B. G., Ferreira-Silva, R., Goya, T. T., Lima, M. F., Rodrigues, A. C. T., Drager, L. F., Jordão, C. P., Rodrigues, A. G., Alves, M. J. N. N., Lorenzi-Filho, G., Negrão, C. E., & Ueno-Pardi, L. M. (2022). Effects of Exercise Training on Left Ventricular Diastolic Function Markers in Patients with Obstructive Sleep Apnea: A Randomized Study. International Journal of Cardiovascular Sciences, 35(5), 646-656.

Formato de Documento Eletrônico (ISO)

Durante, Bruno G. and Ferreira-Silva, Rosyvaldo and Goya, Thiago T. and Lima, Marta F. and Rodrigues, Ana Clara T. and Drager, Luciano F. and Jordão, Camila P. and Rodrigues, Amanda G. and Alves, Maria Janieire de Nazare N. and Lorenzi-Filho, Geraldo and Negrão, Carlos E. and Ueno-Pardi, Linda M.. Effects of Exercise Training on Left Ventricular Diastolic Function Markers in Patients with Obstructive Sleep Apnea: A Randomized Study. International Journal of Cardiovascular Sciences [online]. 2022, vol. 35, n. 5, [citado 2026-10-14], pp. 646-656. Disponível em: <https://journals.cardiol.br/article/effects-of-exercise-training-on-left-ventricular-diastolic-function-markers-in-patients-with-obstructive-sleep-apnea-a-randomized-study-2/>. ISSN 2359-4802

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