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  2. Keyword: Periodontal disease
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Artigo Original

Association between periodontal disease and acute coronary syndrome

Rafael Luiz Rech et al. Natálio Nurkin Ivana da Cruz Fabiano Sostizzo … Carolina Baião José Antônio Perrone Rodrigo Wainstein Daniela Pretto Euler Roberto Fernandes Manenti Luiz Carlos Bodanese

OBJECTIVE: To evaluate the relationship between PD and ACS and the association of PD and periodontitis in ACS patients. METHODS: Fifty-eight ACS patients and 57 controls with no history of coronary artery disease (CAD) were included in the study. Variables: arterial hypertension, diabetes, dyslipidemia, obesity, history of CAD, cigarette smoking, and interleukin-1beta gene polymorphism. RESULTS: One hundred and fifteen subjects were enrolled in the study. In the ACS group, 58 patients were evaluated, 32 of whom (55.2%) were male and 26 (44.8%), female. In the control group, 57 subjects were evaluated, 32 (56.1%) of whom were male and 25 (43.9%), female. Periodontal disease was diagnosed in 26 (44.8%) ACS patients and 15 (26.6%) control patients (beta2 = 4.43, p = 0.04). In a logistic regression analysis, the odds ratio for association between PD and ACS was 1.8 (95% CI: 1.0-5.0); p = 0.24. The odds ratio for association of periodontitis with ACS was 4.5 (95% CI: 1.3-15.6); p = 0.019. CONCLUSION: No independent association was found between PD and ACS. There was an independent association between periodontitis and ACS.

  • Coronary Disease
  • Periodontal disease
  • Periodontitis
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Creative Commons Attribution (CC BY) Creative Commons license
20/03/2007 DOI: 10.1590/S0066-782X2007000200009
ABC
Artigo Original

Periodontal disease as a potential risk factor for acute coronary syndromes

Renata Accarini et al. Moacir Fernandes de Godoy

OBJECTIVE: To investigate whether there is a relationship between active periodontal disease (PD) and acute coronary syndromes (ACS). METHODS: Three hundred and sixty-one patients (57,3% male), ages ranging from 27 to 89 (mean ± DP = 60.5 ± 12.2), were admitted to the Intensive Care Unit of a Teaching Hospital with symptoms and complementary examinations consistent with acute coronary syndrome. All the patients had a complete periodontal examination in the ICU setting, and 325 (90.9%) underwent coronary angiography for diagnostic confirmation and/or treatment planning. Periodontal examination included evaluation of all the teeth in the oral cavity and the following parameters: probing depth, clinical attachment level, plaque index, and gingival index. RESULTS: Of the 325 patients, 91 (28%) had coronary arteries free of obstruction or with mild obstructions (< 50% diameter stenosis), and the remaining 72% had severe obstructions. Fisher's exact text yielded a p value of 0.0245 with an odds ratio of 2.571 (95% CI 1.192 to 5.547), meaning that the group with ACS and significant obstructive coronary artery disease was 2.5-fold more likely to have active PD. CONCLUSION: A significant association was found between active periodontal disease and severe obstructive coronary artery in patients with acute coronary syndrome, underscoring the importance of prevention and adequate treatment of periodontal disease, which should be considered as a potential risk factor in the etiology and instability of the atherosclerotic plaque.

  • Acute coronary syndrome
  • coronary atherosclerosis
  • Inflammation
  • obstructive coronary artery disease
  • Periodontal disease
  • Risk Factor
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06/03/2007 DOI: 10.1590/S0066-782X2006001800007
ABC
Artigo Original

Periodontal disease in patients with ischemic coronary atherosclerosis at a University Hospital

Ana Lúcia Azevedo Barilli et al. Afonso Dinis Costa Passos José Antônio Marin-Neto Laércio Joel Franco

OBJECTIVE: To verify the prevalence of periodontal disease (PD) in patients with ischemic heart disease. PD is a serious public dental health care problem with a differentiated distribution in regards to severity, age group, type of infection, co-morbidities and risk factors. METHODS: Four hundred and eighty patients were examined at the Ischemic Cardiopathy Outpatient Clinic of the Hospital das Clínicas of the Ribeirão Preto Medical School, São Paulo University, as well as 154 patients without heart disease from the same institution. Fifty-eight patients with heart disease and 62 patients without heart disease between the ages of 30 and 79 met the criteria to be included in the investigation. In accordance with recommendations of WHO (1999) the Community Periodontal Index (CPI) and the Periodontal Attachment Loss Index (PALI) were used. RESULTS: Patients with heart disease had a prevalence of sextants with moderate to advanced PD (76.3% versus 20.2%; p < 0.00001). In these patients, 1.1% of the sextants were found to be healthy versus 32.0% of those without heart disease (p < 0.00001). In regards to the progression of PD, 6.0% of the sextants of the patients with heart disease did not exhibit attachment loss versus 68.0% of those without heart disease (p < 0.00001). Dental biofilm was observed in 100.0% of the patients with heart disease and in 82.3% of those without heart disease (p 6 mm was required in 79.3% of the patients with heart disease versus 9.7% of those without heart disease (p < 0.0001). CONCLUSION: PD was very prevalent in the groups studied with a higher degree of severity in those with ischemic heart diseases. The elevated prevalence of risk factors found, indicates that intervention strategies are required.

  • Heart Diseases
  • periodontal attachment loss
  • Periodontal disease
  • periodontal index
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18/01/2007 DOI: 10.1590/S0066-782X2006001900003

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Rech RL, Nurkin N, Cruz I, Sostizzo F, Baião C, Perrone JA, Wainstein R, et al. Association between periodontal disease and acute coronary syndrome. Arquivos Brasileiros de Cardiologia 2007;88(2):185-90.

Electronic Document Format (ABNT)

Rech, Rafael Luiz; Nurkin, Natálio; Cruz, Ivana da; Sostizzo, Fabiano; Baião, Carolina; Perrone, José Antônio; Wainstein, Rodrigo; Pretto, Daniela; Manenti, Euler Roberto Fernandes; Bodanese, Luiz Carlos. Association between periodontal disease and acute coronary syndrome. Arquivos Brasileiros de Cardiologia, v. 88, n. 2, p. 185-190, Mar. 2007.

Electronic Document Format (APA)

Rech, R. L., Nurkin, N., Cruz, I. , Sostizzo, F., Baião, C., Perrone, J. A., Wainstein, R., Pretto, D., Manenti, E. R. F., & Bodanese, L. C. (2007). Association between periodontal disease and acute coronary syndrome. Arquivos Brasileiros de Cardiologia, 88(2), 185-190.

Electronic Document Format (ISO)

Rech, Rafael Luiz and Nurkin, Natálio and Cruz, Ivana da and Sostizzo, Fabiano and Baião, Carolina and Perrone, José Antônio and Wainstein, Rodrigo and Pretto, Daniela and Manenti, Euler Roberto Fernandes and Bodanese, Luiz Carlos. Association between periodontal disease and acute coronary syndrome. Arquivos Brasileiros de Cardiologia [online]. 2007, vol. 88, n. 2, [cited 2026-10-14], pp. 185-190. Available from: <https://journals.cardiol.br/en/article/association-between-periodontal-disease-and-acute-coronary-syndrome/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Accarini R, Godoy MF. Periodontal disease as a potential risk factor for acute coronary syndromes. Arquivos Brasileiros de Cardiologia 2007;87(5):592-6.

Electronic Document Format (ABNT)

Accarini, Renata; Godoy, Moacir Fernandes de. Periodontal disease as a potential risk factor for acute coronary syndromes. Arquivos Brasileiros de Cardiologia, v. 87, n. 5, p. 592-596, Mar. 2007.

Electronic Document Format (APA)

Accarini, R., & Godoy, M. F. (2007). Periodontal disease as a potential risk factor for acute coronary syndromes. Arquivos Brasileiros de Cardiologia, 87(5), 592-596.

Electronic Document Format (ISO)

Accarini, Renata and Godoy, Moacir Fernandes de. Periodontal disease as a potential risk factor for acute coronary syndromes. Arquivos Brasileiros de Cardiologia [online]. 2007, vol. 87, n. 5, [cited 2026-10-14], pp. 592-596. Available from: <https://journals.cardiol.br/en/article/periodontal-disease-as-a-potential-risk-factor-for-acute-coronary-syndromes-2/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Barilli ALA, Passos ADC, Marin-Neto JA, Franco LJ. Periodontal disease in patients with ischemic coronary atherosclerosis at a University Hospital. Arquivos Brasileiros de Cardiologia 2007;87(6):695-700.

Electronic Document Format (ABNT)

Barilli, Ana Lúcia Azevedo; Passos, Afonso Dinis Costa; Marin-Neto, José Antônio; Franco, Laércio Joel. Periodontal disease in patients with ischemic coronary atherosclerosis at a University Hospital. Arquivos Brasileiros de Cardiologia, v. 87, n. 6, p. 695-700, Jan. 2007.

Electronic Document Format (APA)

Barilli, A. L. A., Passos, A. D. C., Marin-Neto, J. A., & Franco, L. J. (2007). Periodontal disease in patients with ischemic coronary atherosclerosis at a University Hospital. Arquivos Brasileiros de Cardiologia, 87(6), 695-700.

Electronic Document Format (ISO)

Barilli, Ana Lúcia Azevedo and Passos, Afonso Dinis Costa and Marin-Neto, José Antônio and Franco, Laércio Joel. Periodontal disease in patients with ischemic coronary atherosclerosis at a University Hospital. Arquivos Brasileiros de Cardiologia [online]. 2007, vol. 87, n. 6, [cited 2026-10-14], pp. 695-700. Available from: <https://journals.cardiol.br/en/article/periodontal-disease-in-patients-with-ischemic-coronary-atherosclerosis-at-a-university-hospital/>. ISSN 0066-782X

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