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  2. Keyword: in-hospital lethality
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Artigo Original

Predictors of in-hospital lethality in patients with advanced heart failure

Adriana Lopes Latado et al. Luiz Carlos Santana Passos Julio C. V. Braga Alessandra Santos … Rodrigo Guedes Simone S. Moura Daniela Almeida

OBJECTIVE: Describe the clinical characteristics and identify potential risk factors for in-hospital lethality in patients with decompensated heart failure admitted to an intensive care unit. METHODS: Decompensated heart failure patients consecutively admitted to an intensive care unit between June 2001 and December 2003 were selected and followed during hospitalization until discharge or death. Clinical characteristics at admission were recorded and evaluated as independent risk predictors for in-hospital mortality by multiple logistic regression analysis. RESULTS: A total of 299 patients (69±13 years of age and 54% men) were enrolled. Coronary artery disease was the main cause of heart failure in 49% of the cases. Diabetes mellitus and systemic arterial hypertension occurred in 37.5% and 78% of the patients, respectively. At admission, 22% of them had atrial fibrillation, 21.5% had renal dysfunction, and 48% anemia (16.5% with severe anemia). Severe systolic dysfunction (left ventricular ejection fraction 70 years, and hyponatremia were independently associated with in-hospital mortality. CONCLUSION: Patients admitted to an intensive care unit due to decompensated heart failure have high in-hospital lethality. In this study, variables recorded at admission, such as previous stroke, atrial fibrillation, hyponatremia, renal failure, and age > 70 years were predictors of in-hospital lethality.

  • Epidemiology
  • Heart Failure
  • in-hospital lethality
  • predictors
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Creative Commons Attribution (CC BY) Creative Commons license
28/09/2006 DOI: 10.1590/S0066-782X2006001500018 Views 2
Temporal tendency of in-hospital lethality due to acute myocardial infarction: 1994-2003
ABC
Artigo Original

Temporal tendency of in-hospital lethality due to acute myocardial infarction: 1994-2003

Marco Antonio de Mattos et al. Daniele Gusmão Toledo Carlos Eduardo de Mattos Bernardo Rangel Tura … Diego Neri Benevides Gadelha Aristarco Gonçalves de Siqueira Filho

OBJECTIVE: To analyze the temporal tendency of lethality due to acute myocardial infarction (AMI) and if the change in behavior directly interfered in such lethality. METHODS: 1055 non-selected patients, who were hospitalized in coronary unit from 1994 to 2003, were assessed. Clinical and therapeutic profile-related variables were analyzed. The statistic analysis used the exponential damping of temporal series and other techniques, such as the logistic linear regression. RESULTS: The average lethality was 10.8%, being 12% in 1994 and 7% in 2002 (p=0.000), a relative reduction of 58%. There was no significant variation in the risk profile of the patients. There were 67.4% of men and 32.4% of women, with an average age of 60.93 and 64.84 years old, respectively. It was observed a significant increase in the percentage of cardiac catheterization (from 14% to 51%), in the angioplasty carried out 24 hours after the infarction (from 2% to 33%), in the surgery for myocardial revascularization (from 4% to 7%) and in the primary angioplasty (from 4% to 11%) with p=0.000, p=0.021, p=0.000 and p=0.000, respectively, for linear tendency. In the first 24 hours there was an increase of the use of aspirin and beta-blockers, from 78% to 100% and, from 33% to 76% (p=0.003 and p=0.004, respectively) along the years. After the analysis, the myocardial reperfusion therapy, the use of aspirin and beta-blocker in the first 24 hours of the AMI (p=0.010, p=0.024 and p=0.035, respectively) kept on being lethality determiners. CONCLUSION: There was a decrease in lethality and the change of behavior in the treatment of AMI along the years was responsible for the reduction of lethality in that temporal series.

  • Acute Myocardial Infarction
  • in-hospital lethality
  • temporal tendency
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24/05/2005 DOI: 10.1590/S0066-782X2005000500012 Views 1

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Latado AL, Passos LCS, Braga JCV, Santos A, Guedes R, Moura SS, Almeida D, et al. Predictors of in-hospital lethality in patients with advanced heart failure. Arquivos Brasileiros de Cardiologia 2006;87(2):185-92.

Electronic Document Format (ABNT)

Latado, Adriana Lopes; Passos, Luiz Carlos Santana; Braga, Julio C. V.; Santos, Alessandra; Guedes, Rodrigo; Moura, Simone S.; Almeida, Daniela. Predictors of in-hospital lethality in patients with advanced heart failure. Arquivos Brasileiros de Cardiologia, v. 87, n. 2, p. 185-192, Sep. 2006.

Electronic Document Format (APA)

Latado, A. L., Passos, L. C. S., Braga, J. C. V., Santos, A., Guedes, R., Moura, S. S., & Almeida, D. (2006). Predictors of in-hospital lethality in patients with advanced heart failure. Arquivos Brasileiros de Cardiologia, 87(2), 185-192.

Electronic Document Format (ISO)

Latado, Adriana Lopes and Passos, Luiz Carlos Santana and Braga, Julio C. V. and Santos, Alessandra and Guedes, Rodrigo and Moura, Simone S. and Almeida, Daniela. Predictors of in-hospital lethality in patients with advanced heart failure. Arquivos Brasileiros de Cardiologia [online]. 2006, vol. 87, n. 2, [cited 2026-10-14], pp. 185-192. Available from: <https://journals.cardiol.br/en/article/predictors-of-in-hospital-lethality-in-patients-with-advanced-heart-failure/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Mattos MA, Toledo DG, Mattos CE, Tura BR, Gadelha DNB, Siqueira Filho AG. Temporal tendency of in-hospital lethality due to acute myocardial infarction: 1994-2003. Arquivos Brasileiros de Cardiologia 2005;84(5):416-21.

Electronic Document Format (ABNT)

Mattos, Marco Antonio de; Toledo, Daniele Gusmão; Mattos, Carlos Eduardo de; Tura, Bernardo Rangel; Gadelha, Diego Neri Benevides; Siqueira Filho, Aristarco Gonçalves de. Temporal tendency of in-hospital lethality due to acute myocardial infarction: 1994-2003. Arquivos Brasileiros de Cardiologia, v. 84, n. 5, p. 416-421, May. 2005.

Electronic Document Format (APA)

Mattos, M. A. , Toledo, D. G., Mattos, C. E. , Tura, B. R., Gadelha, D. N. B., & Siqueira Filho, A. G. (2005). Temporal tendency of in-hospital lethality due to acute myocardial infarction: 1994-2003. Arquivos Brasileiros de Cardiologia, 84(5), 416-421.

Electronic Document Format (ISO)

Mattos, Marco Antonio de and Toledo, Daniele Gusmão and Mattos, Carlos Eduardo de and Tura, Bernardo Rangel and Gadelha, Diego Neri Benevides and Siqueira Filho, Aristarco Gonçalves de. Temporal tendency of in-hospital lethality due to acute myocardial infarction: 1994-2003. Arquivos Brasileiros de Cardiologia [online]. 2005, vol. 84, n. 5, [cited 2026-10-14], pp. 416-421. Available from: <https://journals.cardiol.br/en/article/temporal-tendency-of-in-hospital-lethality-due-to-acute-myocardial-infarction-1994-2003/>. ISSN 0066-782X

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