ABC Family Arquivos Brasileiros de Cardiologia International Journal of Cardiovascular Sciences ABC Heart Failure & Cardiomyopathy ABC Imagem Cardiovascular
Português English
ABC Family
Português English
  • About
    • About ABC Family
    • Internal Regulation
    • Editorial Board
    • Brazilian Society of Cardiology (SBC)
  • Issues
  • SBC Guidelines
  • Content
    • Videos
    • Podcasts
    • News
  • About
    • About ABC Family
    • Internal Regulation
    • Editorial Board
    • Brazilian Society of Cardiology (SBC)
  • Issues
  • SBC Guidelines
  • Content
    • Videos
    • Podcasts
    • News

ABC Family

  • ABC Family
  • Arquivos Brasileiros de Cardiologia
  • International Journal of Cardiovascular Sciences
  • ABC Heart Failure & Cardiomyopathy
  • ABC Imagem Cardiovascular
Search in

No content found.

Journals
Ordering
Article types
Others

  1. Home
  2. Keyword: Heart Ventricles/physiopathology
Figure 1
ABC
Case Report

Symptomatic Exercise-induced Intraventricular Gradient in Competitive Athlete

Helder Dores et al. Lígia Mendes António Ferreira Jose Ferreira Santos

Case Report

We describe the case of a 17-year-old caucasian male tennis player, training a mean of 20-24h/week, refereed for evaluation in Sport’s Cardiology clinic due to symptoms of dizziness on strenuous exercise, relieving soon after decubitus. The athlete denied other concomitant complaints, namely thoracic pain, palpitations, syncope or decrease in physical performance. Although this is the most symptomatic episode, he revealed other prior episodes with similar presentation, but less intense and occurring in environments with high temperatures. Personal/family history was unremarkable and all pre-competitive evaluations were normal and without restrictions for competitive sport. Physical examination did not show significant findings – cardiac evaluation was normal, heart rate and blood pressure at rest were 52 bpm 121/64mmHg respectively.

The 12-lead electrocardiogram and transthoracic echocardiogram did not show pathological findings, only cardiac physiological adaptations to exercise (). Subsequently the athlete underwent a treadmill exercise stress echocardiogram revealing an excellent functional capacity (19’09’’ of Bruce protocol, 19.3METs), but with reproduction of symptoms (dizziness) in the peak of exercise with simultaneous decrease in systolic blood pressure (185➔90mmHg) and detection of intraventricular gradient (IVG) – at least 69mmHg (). In the first minute of recovery the symptoms disappeared and blood pressure normalized.

[…]

  • Athletes
  • Echocardiography, Stress
  • Exercise Test/adverse effects
  • Heart Ventricles/physiopathology
  • Ventricular Dysfunction/etiology
Read Full Article
Creative Commons Attribution (CC BY) Creative Commons license
01/07/2017 DOI: 10.5935/abc.20170075
ABC
Original Article

Galectin-3: A Link between Myocardial and Arterial Stiffening in Patients with Acute Decompensated Heart Failure?

Radu Ioan Lala et al. Dan Darabantiu Luminita Pilat Maria Puschita

Abstract

Background:

Heart failure is accompanied by abnormalities in ventricular-vascular interaction due to increased myocardial and arterial stiffness. Galectin-3 is a recently discovered biomarker that plays an important role in myocardial and vascular fibrosis and heart failure progression.

Objectives:

The aim of this study was to determine whether galectin-3 is correlated with arterial stiffening markers and impaired ventricular-arterial coupling in decompensated heart failure patients.

Methods:

A total of 79 inpatients with acute decompensated heart failure were evaluated. Serum galectin-3 was determined at baseline, and during admission, transthoracic echocardiography and measurements of vascular indices by Doppler ultrasonography were performed.

Results:

Elevated pulse wave velocity and low arterial carotid distensibility are associated with heart failure in patients with preserved ejection fraction (p = 0.04, p = 0.009). Pulse wave velocity, carotid distensibility and Young’s modulus did not correlate with serum galectin-3 levels. Conversely, raised galectin-3 levels correlated with an increased ventricular-arterial coupling ratio (Ea/Elv) p = 0.047, OR = 1.9, 95% CI (1.0‑3.6). Increased galectin-3 levels were associated with lower rates of left ventricular pressure rise in early systole (dp/dt) (p=0.018) and raised pulmonary artery pressure (p = 0.046). High galectin-3 levels (p = 0.038, HR = 3.07) and arterial pulmonary pressure (p = 0.007, HR = 1.06) were found to be independent risk factors for all-cause mortality and readmissions.

Conclusions:

This study showed no significant correlation between serum galectin-3 levels and arterial stiffening markers. Instead, high galectin-3 levels predicted impaired ventricular-arterial coupling. Galectin-3 may be predictive of raised pulmonary artery pressures. Elevated galectin-3 levels correlate with severe systolic dysfunction and together with pulmonary hypertension are independent markers of outcome.

  • Biomarkers, Pharmacological
  • Echocardiography
  • Galectin 3/analysis
  • Heart Failure/pathology
  • Heart Ventricles/physiopathology
  • Vascular Stiffness
Read Full Article
Creative Commons Attribution (CC BY) Creative Commons license
12/01/2016 DOI: 10.5935/abc.20150149

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Dores H, Mendes L, Ferreira A, Santos JF. Symptomatic Exercise-induced Intraventricular Gradient in Competitive Athlete. Arquivos Brasileiros de Cardiologia 2017;109(1):87-9.

Electronic Document Format (ABNT)

Dores, Helder; Mendes, Lígia; Ferreira, António; Santos, Jose Ferreira. Symptomatic Exercise-induced Intraventricular Gradient in Competitive Athlete. Arquivos Brasileiros de Cardiologia, v. 109, n. 1, p. 87-89, Jun. 2017.

Electronic Document Format (APA)

Dores, H., Mendes, L., Ferreira, A., & Santos, J. F. (2017). Symptomatic Exercise-induced Intraventricular Gradient in Competitive Athlete. Arquivos Brasileiros de Cardiologia, 109(1), 87-89.

Electronic Document Format (ISO)

Dores, Helder and Mendes, Lígia and Ferreira, António and Santos, Jose Ferreira. Symptomatic Exercise-induced Intraventricular Gradient in Competitive Athlete. Arquivos Brasileiros de Cardiologia [online]. 2017, vol. 109, n. 1, [cited 2026-10-14], pp. 87-89. Available from: <https://journals.cardiol.br/en/article/symptomatic-exercise-induced-intraventricular-gradient-in-competitive-athlete/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Lala RI, Darabantiu D, Pilat L, Puschita M. Galectin-3: A Link between Myocardial and Arterial Stiffening in Patients with Acute Decompensated Heart Failure?. Arquivos Brasileiros de Cardiologia 2016;106(2):121-9.

Electronic Document Format (ABNT)

Lala, Radu Ioan; Darabantiu, Dan; Pilat, Luminita; Puschita, Maria. Galectin-3: A Link between Myocardial and Arterial Stiffening in Patients with Acute Decompensated Heart Failure?. Arquivos Brasileiros de Cardiologia, v. 106, n. 2, p. 121-129, Jan. 2016.

Electronic Document Format (APA)

Lala, R. I., Darabantiu, D., Pilat, L., & Puschita, M. (2016). Galectin-3: A Link between Myocardial and Arterial Stiffening in Patients with Acute Decompensated Heart Failure?. Arquivos Brasileiros de Cardiologia, 106(2), 121-129.

Electronic Document Format (ISO)

Lala, Radu Ioan and Darabantiu, Dan and Pilat, Luminita and Puschita, Maria. Galectin-3: A Link between Myocardial and Arterial Stiffening in Patients with Acute Decompensated Heart Failure?. Arquivos Brasileiros de Cardiologia [online]. 2016, vol. 106, n. 2, [cited 2026-10-14], pp. 121-129. Available from: <https://journals.cardiol.br/en/article/galectin-3-a-link-between-myocardial-and-arterial-stiffening-in-patients-with-acute-decompensated-heart-failure/>. ISSN 0066-782X

  • About ABC Family
  • Internal Regulation
  • Editorial Board
  • Brazilian Society of Cardiology (SBC)

Issues

SBC Guidelines

  • Videos
  • Podcasts
  • News