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  2. Keyword: Heart Defects Congenital/mortality
IJCS
Editorial

Risk Factors for Mortality in Pediatric Cardiac Intensive Care Unit

Cristiane Martins et al. Bruna M. N. Gama

Congenital heart defect commonly requires care in pediatric intensive care unit (PICU). They are a heterogeneous group of disorders with an annual incidence of 25,757 new cases in Brazil, 12 cases per 1,000 inhabitants . In this paper, Guimarães et al., published a cross-sectional study to describe the epidemiology of patients admitted to PICU from a tertiary hospital in Brazil. In this editorial, we review recent progress in understanding the risk factors for mortality in PICU. The editorial was produced by searching Pubmed and Scielo, using the terms “PICU”, “RACHS”, “CHD”, and “mortality”.

Congenital heart defects (CHD) are serious and common conditions that have a significant impact on morbidity, mortality and healthcare costs in both children and adults. It is estimated that at least 32,000 infants in the United States will be affected each year by CHD. Of these, approximately 25%, or 2.4 per 1,000 live births require invasive treatment in the first year of life. While advances in treatment in the last decades have decreased infant mortality, they have also led to an increase in the number of children and adults with CHD. Despite these advances and developments in interventional and surgical techniques, heart disease in children remains an important cause of morbidity and mortality.

[…]

  • Aortic Coarctation
  • Arterial Switch Operation
  • Heart Defects Congenital/mortality
  • Heart Septal Defects, Ventricular
  • Hospitalization
  • Intensive Care Units
  • Mordity
  • Risk Factors
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Creative Commons Attribution (CC BY) Creative Commons license
31/07/2020 DOI: 10.36660/ijcs.20200130 Views 1
Figure 1
ABC
Original Article

Mortality for Critical Congenital Heart Diseases and Associated Risk Factors in Newborns. A Cohort Study

Selma Alves Valente do Amaral Lopes et al. Isabel Cristina Britto Guimarães Sofia Fontes de Oliva Costa Angelina Xavier Acosta … Kyoko Abe Sandes Carlos Maurício Cardeal Mendes

Abstract

Background:

Congenital heart diseases are the most common type of congenital defects, and account for more deaths in the first year of life than any other condition, when infectious etiologies are ruled out.

Objectives:

To evaluate survival, and to identify risk factors in deaths in newborns with critical and/or complex congenital heart disease in the neonatal period.

Methods:

A cohort study, nested to a randomized case-control, was performed, considering the Confidence Interval of 95% (95% CI) and significance level of 5%, paired by gender of the newborn and maternal age. Case-finding, interviews, medical record analysis, clinical evaluation of pulse oximetry (heart test) and Doppler echocardiogram were performed, as well as survival analysis, and identification of death-related risk factors.

Results:

The risk factors found were newborns younger than 37 weeks (Relative Risk – RR: 2.89; 95% CI [1.49-5.56]; p = 0.0015), weight of less than 2,500 grams (RR: 2.33 [; 95% CI 1.26-4.29]; p = 0.0068), occurrence of twinning (RR: 11.96 [95% CI 1.43-99.85]; p = 0.022) and presence of comorbidity (RR: 2.27 [95% CI 1.58-3.26]; p < 0.0001). The incidence rate of mortality from congenital heart disease was 81 cases per 100,000 live births. The lethality attributed to critical congenital heart diseases was 64.7%, with proportional mortality of 12.0%. The survival rate at 28 days of life decreased by almost 70% in newborns with congenital heart disease. The main cause of death was cardiogenic shock.

Conclusion:

Preterm infants with low birth weight and comorbidities presented a higher risk of mortality related to congenital heart diseases. This cohort was extinguished very quickly, signaling the need for greater investment in assistance technology in populations with this profile.

  • Heart Defects Congenital/mortality
  • Infant Newborn/mortality
  • Risk Factors
  • Survival Analysis
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Creative Commons Attribution (CC BY) Creative Commons license
21/09/2018 DOI: 10.5935/abc.20180175
Figure 1
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Original Article

Mortality from Circulatory System Diseases and Malformations in Children in the State of Rio de Janeiro

Thais Rocha Salim et al. Gabriel Porto Soares Carlos Henrique Klein Glaucia Maria Moraes de Oliveira

Abstract

Background:

The epidemiological profile of mortality in a population is important for the institution of measures to improve health care and reduce mortality

Objective:

To estimate mortality rates and the proportional mortality from cardiovascular diseases and malformations of the circulatory system in children and adolescents.

Methods:

This is a descriptive study of mortality from cardiovascular diseases, malformations of the circulatory system, from all causes, ill-defined causes and external causes in children and adolescents in the state of Rio de Janeiro from 1996 to 2012. Populations were obtained from the Brazilian Institute of Geography and Statistics (Instituto Brasileiro de Geografia e Estatística – IBGE) and deaths obtained from the Department of Informatics of the Unified Health System (DATASUS)/Ministry of Health.

Results:

There were 115,728 deaths from all causes, 69,757 in males. The annual mortality from cardiovascular diseases was 2.7/100,000 in men and 2.6/100,000 in women. The annual mortality from malformations of the circulatory system was 7.5/100,000 in men and 6.6/100,000 in women. Among the specific causes of circulatory diseases, cardiomyopathies had the highest rates of annual proportional mortality, and from malformations of the circulatory system, it occurred due to unspecified malformations of the circulatory system, at all ages and in both genders.

Conclusion:

Mortality from malformations of the circulatory system was most striking in the first years of life, while cardiovascular diseases were more relevant in adolescents. Low access to prenatal diagnosis or at birth probably prevented the proper treatment of malformations of the circulatory system.

  • Cardiovascular Defects
  • Child Mortality
  • Heart Defects Congenital/mortality
  • Heart Defects, Congenital / epidemiology
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Creative Commons Attribution (CC BY) Creative Commons license
17/05/2016 DOI: 10.5935/abc.20160069

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Martins C, Gama BMN. Risk Factors for Mortality in Pediatric Cardiac Intensive Care Unit. International Journal of Cardiovascular Sciences 2020;33(4):337-9.

Electronic Document Format (ABNT)

Martins, Cristiane; Gama, Bruna M. N.. Risk Factors for Mortality in Pediatric Cardiac Intensive Care Unit. International Journal of Cardiovascular Sciences, v. 33, n. 4, p. 337-339, Jul. 2020.

Electronic Document Format (APA)

Martins, C., & Gama, B. M. N. (2020). Risk Factors for Mortality in Pediatric Cardiac Intensive Care Unit. International Journal of Cardiovascular Sciences, 33(4), 337-339.

Electronic Document Format (ISO)

Martins, Cristiane and Gama, Bruna M. N.. Risk Factors for Mortality in Pediatric Cardiac Intensive Care Unit. International Journal of Cardiovascular Sciences [online]. 2020, vol. 33, n. 4, [cited 2026-10-14], pp. 337-339. Available from: <https://journals.cardiol.br/en/article/risk-factors-for-mortality-in-pediatric-cardiac-intensive-care-unit/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Lopes SAVA, Guimarães ICB, Costa SFO, Acosta AX, Sandes KA, Mendes CMC. Mortality for Critical Congenital Heart Diseases and Associated Risk Factors in Newborns. A Cohort Study. Arquivos Brasileiros de Cardiologia 2018;111(5):666-73.

Electronic Document Format (ABNT)

Lopes, Selma Alves Valente do Amaral; Guimarães, Isabel Cristina Britto; Costa, Sofia Fontes de Oliva; Acosta, Angelina Xavier; Sandes, Kyoko Abe; Mendes, Carlos Maurício Cardeal. Mortality for Critical Congenital Heart Diseases and Associated Risk Factors in Newborns. A Cohort Study. Arquivos Brasileiros de Cardiologia, v. 111, n. 5, p. 666-673, Sep. 2018.

Electronic Document Format (APA)

Lopes, S. A. V. A., Guimarães, I. C. B., Costa, S. F. O., Acosta, A. X., Sandes, K. A., & Mendes, C. M. C. (2018). Mortality for Critical Congenital Heart Diseases and Associated Risk Factors in Newborns. A Cohort Study. Arquivos Brasileiros de Cardiologia, 111(5), 666-673.

Electronic Document Format (ISO)

Lopes, Selma Alves Valente do Amaral and Guimarães, Isabel Cristina Britto and Costa, Sofia Fontes de Oliva and Acosta, Angelina Xavier and Sandes, Kyoko Abe and Mendes, Carlos Maurício Cardeal. Mortality for Critical Congenital Heart Diseases and Associated Risk Factors in Newborns. A Cohort Study. Arquivos Brasileiros de Cardiologia [online]. 2018, vol. 111, n. 5, [cited 2026-10-14], pp. 666-673. Available from: <https://journals.cardiol.br/en/article/mortality-for-critical-congenital-heart-diseases-and-associated-risk-factors-in-newborns-a-cohort-study/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Salim TR, Soares GP, Klein CH, Oliveira GMM. Mortality from Circulatory System Diseases and Malformations in Children in the State of Rio de Janeiro. Arquivos Brasileiros de Cardiologia 2016;106(6):464-73.

Electronic Document Format (ABNT)

Salim, Thais Rocha; Soares, Gabriel Porto; Klein, Carlos Henrique; Oliveira, Glaucia Maria Moraes de. Mortality from Circulatory System Diseases and Malformations in Children in the State of Rio de Janeiro. Arquivos Brasileiros de Cardiologia, v. 106, n. 6, p. 464-473, May. 2016.

Electronic Document Format (APA)

Salim, T. R., Soares, G. P., Klein, C. H., & Oliveira, G. M. M. (2016). Mortality from Circulatory System Diseases and Malformations in Children in the State of Rio de Janeiro. Arquivos Brasileiros de Cardiologia, 106(6), 464-473.

Electronic Document Format (ISO)

Salim, Thais Rocha and Soares, Gabriel Porto and Klein, Carlos Henrique and Oliveira, Glaucia Maria Moraes de. Mortality from Circulatory System Diseases and Malformations in Children in the State of Rio de Janeiro. Arquivos Brasileiros de Cardiologia [online]. 2016, vol. 106, n. 6, [cited 2026-10-14], pp. 464-473. Available from: <https://journals.cardiol.br/en/article/mortality-from-circulatory-system-diseases-and-malformations-in-children-in-the-state-of-rio-de-janeiro/>. ISSN 0066-782X

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