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  2. Palavra-chave: Mitral Valve Stenosis
IJCS
Case Report

Cerebral Thromboembolism as a Primary Manifestation of Severe Rheumatic Mitral Stenosis: A Clinical Case from Guayaquil, Ecuador

Patricia Delgado Cedeño et al. Estefania Carolina Arteaga Herrera Cesar Joao Tumbaco Mite Elsie Valdivieso Valenzuela … Boris Barreno Vera Karen Llimaico Del Pin

Abstract

Mitral stenosis (MS) is a valvular disease that predominantly affects women, with rheumatic fever being the most prevalent etiological cause. The hemodynamic consequences of rheumatic MS may include left atrial (LA) pressure overload and dilation, atrial fibrillation (AF), secondary pulmonary hypertension, heart failure, atrial thrombosis, and systemic thromboembolism. Echocardiography is the gold standard for diagnosing, quantifying severity, and evaluating the hemodynamic impact of MS.

We present the case of a 41-year-old female patient who arrived at the emergency department with a 6-hour history of dysarthria and right hemiparesis. Cardiovascular examination revealed sinus rhythm and a diastolic murmur with an opening snap at the mitral focus. Imaging studies revealed severe MS with LA dilation and a patent foramen ovale without hemodynamic impact. The patient underwent percutaneous balloon mitral valvuloplasty, which resulted in an increase in mitral valve area (MVA), a reduction in pulmonary pressure, and significant functional improvement.

Cerebral thromboembolism can be the first manifestation of severe MS, even in patients with sinus rhythm. Anticoagulation is crucial for those with severe atrial dilation to reduce the risk of embolic events. This case highlights the importance of early diagnosis and appropriate treatment based on clinical guidelines, as they improve patient quality of life and reduce the risk of future complications. It also serves as a reminder that stroke may be the sentinel event in silent but severe mitral valve pathology.

  • Ischemic Stroke
  • Mitral Valve Stenosis
  • Rheumatic Heart Disease
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Creative Commons Attribution (CC BY) Creative Commons license
01/09/2025 DOI: 10.36660/ijcs.20250013 Visualizações 1

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Formato de Documento Eletrônico (Vancouver)

Cedeño PD, Herrera ECA, Mite CJT, Valenzuela EV, Vera BB, Pin KLD. Cerebral Thromboembolism as a Primary Manifestation of Severe Rheumatic Mitral Stenosis: A Clinical Case from Guayaquil, Ecuador. International Journal of Cardiovascular Sciences 2025;38:e20250013.

Formato de Documento Eletrônico (ABNT)

Cedeño, Patricia Delgado; Herrera, Estefania Carolina Arteaga; Mite, Cesar Joao Tumbaco; Valenzuela, Elsie Valdivieso; Vera, Boris Barreno; Pin, Karen Llimaico Del. Cerebral Thromboembolism as a Primary Manifestation of Severe Rheumatic Mitral Stenosis: A Clinical Case from Guayaquil, Ecuador. International Journal of Cardiovascular Sciences, v. 38, e20250013, ago. 2025.

Formato de Documento Eletrônico (APA)

Cedeño, P. D., Herrera, E. C. A., Mite, C. J. T., Valenzuela, E. V., Vera, B. B., & Pin, K. L. D. (2025). Cerebral Thromboembolism as a Primary Manifestation of Severe Rheumatic Mitral Stenosis: A Clinical Case from Guayaquil, Ecuador. International Journal of Cardiovascular Sciences, 38, e20250013.

Formato de Documento Eletrônico (ISO)

Cedeño, Patricia Delgado and Herrera, Estefania Carolina Arteaga and Mite, Cesar Joao Tumbaco and Valenzuela, Elsie Valdivieso and Vera, Boris Barreno and Pin, Karen Llimaico Del. Cerebral Thromboembolism as a Primary Manifestation of Severe Rheumatic Mitral Stenosis: A Clinical Case from Guayaquil, Ecuador. International Journal of Cardiovascular Sciences [online]. 2025, vol. 38, [citado 2026-10-14], e20250013. Disponível em: <https://journals.cardiol.br/article/cerebral-thromboembolism-as-a-primary-manifestation-of-severe-rheumatic-mitral-stenosis-a-clinical-case-from-guayaquil-ecuador-2/>. ISSN 2359-4802

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