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  • ABC Heart Failure & Cardiomyopathy
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  4. 2000, Volume 74, Número 2
Updated

Coarctation of the aorta corrected during childhood. Clinical aspects during follow-up

Margarida Maria da Costa Smith Maia et al. Vera Demarchi Aiello Miguel Barbero-Marcial Munir Ebaid

Update

Coarctation of the aorta corrected during childhood. Clinical aspects during follow-up

[…]

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05/09/2000 DOI: 10.1590/S0066-782X2000000200008 Visualizações 4
Case Report

Coronary bilateral ostial enlargement using the saphenous vein in a patient with syphilitic aortitis

Ulisses A. Croti et al. Francisco Gregori Jr Miguel B. Marcial Luís A. Dallan … Thelma Elisa F. Gregori Divina S. Oliveira

A patient with tertiary syphilis presenting with bilateral coronary ostial lesions and aortic regurgitation underwent surgical reconstruction of the coronary ostia by the anterior approach with autogenous saphenous vein grafting and substitution of the aortic valve with a bovine bioprosthesis. The procedure was easily performed and had good outcomes both early and late. The rarity of the association of a lesion in both coronary ostia with aortic regurgitation in syphilis and the surgical technique employed are discussed.

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05/09/2000 DOI: 10.1590/S0066-782X2000000200006 Visualizações 7
Clinicoradiological Session

The patient is a 65-year-old woman with heart failure and proteinuria

Clinicopathologic Session

Clinicopathologic Session

[…]

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05/09/2000 DOI: 10.1590/S0066-782X2000000200007 Visualizações 4
Brief Communication

Great amount of C.pneumoniae in ruptured plaque vessel segments at autopsy. A comparative study with stable plaques

Maria de Lourdes Higuchi et al. Jussara Bianchi Castelli Vera D. Aiello Sueli Palomino … Marcia M. Reis Nadia V. Sambiase Shizie Fukasawa Hiram G. Bezerra José A. F. Ramires

A possible relationship between C.pneumoniae (CP) infection, atherosclerosis and acute myocardial infarction is a debated matter. Now we performed the search of CP in histological segments of fatal ruptured plaques and of stable plaques by histochemistry (Macchiavello stain), immunohistochemistry and in situ hybridization techniques. Electron microscopy and confocal laser microscopy techniques were used in two additional cases. The semi-quantitification of CP + cells (0-4+) and quantification of lymphocytes demonstrated greater amount of CP + cells and more inflammation in the adventitia of vulnerable plaque vessel segments than of stable ones, larger amount of CP + cells in adventitia than in the plaque and high frequency of CP + cells in all groups studied. This preliminary study strongly suggests a direct pathogenetic involvement of adventitial CP in the rupture of the atheromatous plaque, development of acute myocardial infarction and also in the development of atherosclerosis.

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05/09/2000 DOI: 10.1590/S0066-782X2000000200005 Visualizações 6
Original Article

Treatment of persistent rejection with methotrexate in stable patients submitted to heart transplantation

Fernando Bacal et al. Viviane Cordeiro Veiga Alfredo Inácio Fiorelli Giovanni Bellotti … Edimar Alcides Bocchi Noedir Antonio Groppo Stolf José Antonio Franchini Ramires

OBJECTIVE:To evaluate the use of methotrexate for the treatment of recurrent rejection in heart transplant recipients. METHODS: We studied 6 patients submitted to heart transplantation that showed rejection grade > or = 3A (ISHLT) in two consecutives endomyocardial biopsy specimens. The dose was 11.26±3.75mg/week. The evaluated data were: ventricular function, endomyocardial biopsy, white cell count and number of rejection episodes before and after methotrexate administration. RESULTS: There was a reduction in the number of rejection episodes (5.17±1.47 before methotrexate; 2.33±1.75 after 6 months and 3.17±2.99 after 12 months of treatment, p=0.0193). The ventricular function was normal with ejection fraction of 76.5±4.80 before and 75.6±4.59 after methotrexate (p=0.4859). One patient did not finish the treatment because he showed signs of rejection associated with severe pericardial effusion. Five patients had a reduction in the white cell count (8,108±23.72 before and 5650±1350 after methotrexate, p=0.0961). One pulmonary infection with complete resolution after antibiotic treatment was observed. CONCLUSION: Methotrexate in low doses is an effective adjunct therapy in the treatment of recurrent rejection after heart transplantation.

  • Heart Transplantation
  • methotrexate
  • rejection
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05/09/2000 DOI: 10.1590/S0066-782X2000000200004 Visualizações 5
Original Article

Reduction in left ventricular hypertrophy in hypertensive patients treated with enalapril, losartan or the combination of enalapril and losartan

Antônio Carlos Avanza Jr et al. Lilian Mameri El Aouar José Geraldo Mill

OBJECTIVE: To compare the regression of left ventricular hypertrophy in patients with moderate hypertension treated with enalapril, losartan or a combination of the two drugs at lower doses. METHODS: Patients of both sexes with moderate hypertension confirmed by ambulatory monitoring of arte-rial blood pressure and with left ventricular hypertrophy on echocardiogram were assigned to three groups: enalapril (35 mg/day, n=15), losartan (175 mg/day, n=15) and enalapril+losartan (15 mg+100 mg/day, n=16). The patients received the drugs for 10 months. RESULTS: The three therapeutic regimens were equally effective in reducing blood pressure and left ventricular mass index (LVMI, g/m²): 141±3.9 to 123±3.6 in the enalapril group (p<0.05), from 147±3.8 to 133±2.8 in the losartan group (p<0.05), and from 146±3.0 to 116±4.0 in the enalapril+losartan group (p<0.05). However, the percent reduction of LVMI was significantly greater (p<0.01) in the enalapril+losartan group (20.5±5.0%) than in enalapril (12.4±3.2%) and the losartan (9.1±2.1%) groups. Normalization of LVMI was obtained in 10 out of the 16 patients who received enalapril+ losartan, in 6 out of the 15 patients who received only enalapril and in 4 out of the 15 patients treated with losartan. CONCLUSION: The combination of an angiotensin-converting enzyme inhibitor and an angiotensin II receptor antagonist (AT1 receptor antagonist) in patients produced an additional effect on the reduction of left ventricular hypertrophy. This finding may depend on a more complete inhibition of the cardiac renin-angiotensin.

  • angiotensin-converting enzyme
  • cardiac hypertrophy
  • Hypertension
  • losartan
  • renin-angiotensin system
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05/09/2000 DOI: 10.1590/S0066-782X2000000200001 Visualizações 6
Original Article

A new surgical approach for treating dilated cardiomyopathy with mitral regurgitation

Enio Buffolo et al. Ivan Antonio Machado de Paula Honório Palma João Nelson Rodrigues Branco

OBJECTIVE: To evaluate the early outcome of mitral valve prostheses implantation and left ventricular remodeling in 23 patients with end-stage cardiomyopathy and secondary mitral regurgitation (NYHA class III and IV). METHODS: Mitral valvular prosthesis implantation with preservation of papillary muscles and chordae tendinae, and plasty of anteriun cuspid for remodeling of the left ventricle. RESULTS: The surgery was performed in 23 patients, preoperative ejection fraction (echocardiography) varied from 13% to 44% (median: 30%). In 13 patients associated procedures were performed: myocardial revascularization (9), left ventricle plicature repair (3) and aortic prosthese implantation (1). Early deaths (2) occurred on the 4th PO day (cardiogenic shock) and on the 20th PO day (upper gastrointestinal bleeding), and a late death in the second month PO (ventricular arrhythmia). Improvement occurred in NYHA class in 82.6% of the patients (P<0.0001), with a survival rate of 86.9% (mean of 8.9 months of follow-up). CONCLUSION: This technique offers a promising therapeutic alternative for the treatment of patients in refractory heart failure with cardiomyopathy and secondary mitral regurgitation.

  • Dilated Cardiomyopathy
  • mitral implantation
  • mitral insufficiency
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05/09/2000 DOI: 10.1590/S0066-782X2000000200003 Visualizações 6
Original Article

Chlamydia pneumoniae and atherosclerosis. Identification of bacterial DNA in the arterial wall

Mário Sérgio Soares de Azeredo Coutinho et al. Fernando Joo Daniel Nakamae Maria Elizabeth Menezes

OBJECTIVE: The intracellular Gram-negative bacterium Chlamydia pneumoniae has been associated with atherosclerosis. The presence of Chlamydia pneumoniae has been investigated in fragments of the arterial wall with a technique for DNA identification. METHODS: Arterial fragments obtained from vascular surgical procedures in 58 patients were analyzed. From these patients, 39 were males and the mean age was 65±6 years. The polymerase chain reaction was used to identify the bacterial DNA with a pair of primers that codify the major outer membrane protein (MOMP) of Chlamydia pneumoniae. The amplified product was visualized by electrophoresis in the 2% agarose gel stained with ethidium bromide, and it was considered positive when migrating in the band of molecular weight of the positive controls. RESULTS: Seven (12%) out of the 58 patients showed positive results for Chlamydia pneumoniae. CONCLUSION: DNA from Chlamydia pneumoniae was identified in the arterial wall of a substantial number of patients with atherosclerosis. This association, which has already been described in other countries, corroborates the evidence favoring a role played by Chlamydia pneumoniae in atherogenesis.

  • Atherosclerosis
  • Chlamydia pneumoniae
  • polymerase chain reaction
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05/09/2000 DOI: 10.1590/S0066-782X2000000200002 Visualizações 10

Como citar este artigo

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Maia MMCS, Aiello VD, Barbero-Marcial M, Ebaid M. Coarctation of the aorta corrected during childhood. Clinical aspects during follow-up. Arquivos Brasileiros de Cardiologia 2000;74(2):174-80.

Formato de Documento Eletrônico (ABNT)

Maia, Margarida Maria da Costa Smith; Aiello, Vera Demarchi; Barbero-Marcial, Miguel; Ebaid, Munir. Coarctation of the aorta corrected during childhood. Clinical aspects during follow-up. Arquivos Brasileiros de Cardiologia, v. 74, n. 2, p. 174-180, set. 2000.

Formato de Documento Eletrônico (APA)

Maia, M. M. C. S., Aiello, V. D., Barbero-Marcial, M., & Ebaid, M. (2000). Coarctation of the aorta corrected during childhood. Clinical aspects during follow-up. Arquivos Brasileiros de Cardiologia, 74(2), 174-180.

Formato de Documento Eletrônico (ISO)

Maia, Margarida Maria da Costa Smith and Aiello, Vera Demarchi and Barbero-Marcial, Miguel and Ebaid, Munir. Coarctation of the aorta corrected during childhood. Clinical aspects during follow-up. Arquivos Brasileiros de Cardiologia [online]. 2000, vol. 74, n. 2, [citado 2026-11-15], pp. 174-180. Disponível em: <https://journals.cardiol.br/article/coarctation-of-the-aorta-corrected-during-childhood-clinical-aspects-during-follow-up-2/>. ISSN 0066-782X

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Croti UA, Gregori Jr F, Marcial MB, Dallan LA, Gregori TEF, Oliveira DS. Coronary bilateral ostial enlargement using the saphenous vein in a patient with syphilitic aortitis. Arquivos Brasileiros de Cardiologia 2000;74(2):156-8.

Formato de Documento Eletrônico (ABNT)

Croti, Ulisses A.; Gregori Jr, Francisco; Marcial, Miguel B.; Dallan, Luís A.; Gregori, Thelma Elisa F.; Oliveira, Divina S.. Coronary bilateral ostial enlargement using the saphenous vein in a patient with syphilitic aortitis. Arquivos Brasileiros de Cardiologia, v. 74, n. 2, p. 156-158, set. 2000.

Formato de Documento Eletrônico (APA)

Croti, U. A., Gregori Jr, F., Marcial, M. B., Dallan, L. A., Gregori, T. E. F., & Oliveira, D. S. (2000). Coronary bilateral ostial enlargement using the saphenous vein in a patient with syphilitic aortitis. Arquivos Brasileiros de Cardiologia, 74(2), 156-158.

Formato de Documento Eletrônico (ISO)

Croti, Ulisses A. and Gregori Jr, Francisco and Marcial, Miguel B. and Dallan, Luís A. and Gregori, Thelma Elisa F. and Oliveira, Divina S.. Coronary bilateral ostial enlargement using the saphenous vein in a patient with syphilitic aortitis. Arquivos Brasileiros de Cardiologia [online]. 2000, vol. 74, n. 2, [citado 2026-11-15], pp. 156-158. Disponível em: <https://journals.cardiol.br/article/coronary-bilateral-ostial-enlargement-using-the-saphenous-vein-in-a-patient-with-syphilitic-aortitis-2/>. ISSN 0066-782X

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

. The patient is a 65-year-old woman with heart failure and proteinuria. Arquivos Brasileiros de Cardiologia 2000;74(2):163-6.

Formato de Documento Eletrônico (ABNT)

. The patient is a 65-year-old woman with heart failure and proteinuria. Arquivos Brasileiros de Cardiologia, v. 74, n. 2, p. 163-166, set. 2000.

Formato de Documento Eletrônico (APA)

(2000). The patient is a 65-year-old woman with heart failure and proteinuria. Arquivos Brasileiros de Cardiologia, 74(2), 163-166.

Formato de Documento Eletrônico (ISO)

. The patient is a 65-year-old woman with heart failure and proteinuria. Arquivos Brasileiros de Cardiologia [online]. 2000, vol. 74, n. 2, [citado 2026-11-15], pp. 163-166. Disponível em: <https://journals.cardiol.br/article/the-patient-is-a-65-year-old-woman-with-heart-failure-and-proteinuria-2/>. ISSN 0066-782X

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Higuchi ML, Castelli JB, Aiello VD, Palomino S, Reis MM, Sambiase NV, Fukasawa S, et al. Great amount of C.pneumoniae in ruptured plaque vessel segments at autopsy. A comparative study with stable plaques. Arquivos Brasileiros de Cardiologia 2000;74(2):149-51.

Formato de Documento Eletrônico (ABNT)

Higuchi, Maria de Lourdes; Castelli, Jussara Bianchi; Aiello, Vera D.; Palomino, Sueli; Reis, Marcia M.; Sambiase, Nadia V.; Fukasawa, Shizie; Bezerra, Hiram G.; Ramires, José A. F.. Great amount of C.pneumoniae in ruptured plaque vessel segments at autopsy. A comparative study with stable plaques. Arquivos Brasileiros de Cardiologia, v. 74, n. 2, p. 149-151, set. 2000.

Formato de Documento Eletrônico (APA)

Higuchi, M. L., Castelli, J. B., Aiello, V. D., Palomino, S., Reis, M. M., Sambiase, N. V., Fukasawa, S., Bezerra, H. G., & Ramires, J. A. F. (2000). Great amount of C.pneumoniae in ruptured plaque vessel segments at autopsy. A comparative study with stable plaques. Arquivos Brasileiros de Cardiologia, 74(2), 149-151.

Formato de Documento Eletrônico (ISO)

Higuchi, Maria de Lourdes and Castelli, Jussara Bianchi and Aiello, Vera D. and Palomino, Sueli and Reis, Marcia M. and Sambiase, Nadia V. and Fukasawa, Shizie and Bezerra, Hiram G. and Ramires, José A. F.. Great amount of C.pneumoniae in ruptured plaque vessel segments at autopsy. A comparative study with stable plaques. Arquivos Brasileiros de Cardiologia [online]. 2000, vol. 74, n. 2, [citado 2026-11-15], pp. 149-151. Disponível em: <https://journals.cardiol.br/article/great-amount-of-c-pneumoniae-in-ruptured-plaque-vessel-segments-at-autopsy-a-comparative-study-with-stable-plaques-2/>. ISSN 0066-782X

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Bacal F, Veiga VC, Fiorelli AI, Bellotti G, Bocchi EA, Stolf NAG, Ramires JAF, et al. Treatment of persistent rejection with methotrexate in stable patients submitted to heart transplantation. Arquivos Brasileiros de Cardiologia 2000;74(2):145-8.

Formato de Documento Eletrônico (ABNT)

Bacal, Fernando; Veiga, Viviane Cordeiro; Fiorelli, Alfredo Inácio; Bellotti, Giovanni; Bocchi, Edimar Alcides; Stolf, Noedir Antonio Groppo; Ramires, José Antonio Franchini. Treatment of persistent rejection with methotrexate in stable patients submitted to heart transplantation. Arquivos Brasileiros de Cardiologia, v. 74, n. 2, p. 145-148, set. 2000.

Formato de Documento Eletrônico (APA)

Bacal, F., Veiga, V. C., Fiorelli, A. I., Bellotti, G., Bocchi, E. A., Stolf, N. A. G., & Ramires, J. A. F. (2000). Treatment of persistent rejection with methotrexate in stable patients submitted to heart transplantation. Arquivos Brasileiros de Cardiologia, 74(2), 145-148.

Formato de Documento Eletrônico (ISO)

Bacal, Fernando and Veiga, Viviane Cordeiro and Fiorelli, Alfredo Inácio and Bellotti, Giovanni and Bocchi, Edimar Alcides and Stolf, Noedir Antonio Groppo and Ramires, José Antonio Franchini. Treatment of persistent rejection with methotrexate in stable patients submitted to heart transplantation. Arquivos Brasileiros de Cardiologia [online]. 2000, vol. 74, n. 2, [citado 2026-11-15], pp. 145-148. Disponível em: <https://journals.cardiol.br/article/treatment-of-persistent-rejection-with-methotrexate-in-stable-patients-submitted-to-heart-transplantation-2/>. ISSN 0066-782X

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Avanza Jr AC, Aouar LME, Mill JG. Reduction in left ventricular hypertrophy in hypertensive patients treated with enalapril, losartan or the combination of enalapril and losartan. Arquivos Brasileiros de Cardiologia 2000;74(2):111-7.

Formato de Documento Eletrônico (ABNT)

Avanza Jr, Antônio Carlos; Aouar, Lilian Mameri El; Mill, José Geraldo. Reduction in left ventricular hypertrophy in hypertensive patients treated with enalapril, losartan or the combination of enalapril and losartan. Arquivos Brasileiros de Cardiologia, v. 74, n. 2, p. 111-117, set. 2000.

Formato de Documento Eletrônico (APA)

Avanza Jr, A. C., Aouar, L. M. E., & Mill, J. G. (2000). Reduction in left ventricular hypertrophy in hypertensive patients treated with enalapril, losartan or the combination of enalapril and losartan. Arquivos Brasileiros de Cardiologia, 74(2), 111-117.

Formato de Documento Eletrônico (ISO)

Avanza Jr, Antônio Carlos and Aouar, Lilian Mameri El and Mill, José Geraldo. Reduction in left ventricular hypertrophy in hypertensive patients treated with enalapril, losartan or the combination of enalapril and losartan. Arquivos Brasileiros de Cardiologia [online]. 2000, vol. 74, n. 2, [citado 2026-11-15], pp. 111-117. Disponível em: <https://journals.cardiol.br/article/reduction-in-left-ventricular-hypertrophy-in-hypertensive-patients-treated-with-enalapril-losartan-or-the-combination-of-enalapril-and-losartan-2/>. ISSN 0066-782X

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Buffolo E, Paula IAM, Palma H, Branco JNR. A new surgical approach for treating dilated cardiomyopathy with mitral regurgitation. Arquivos Brasileiros de Cardiologia 2000;74(2):135-40.

Formato de Documento Eletrônico (ABNT)

Buffolo, Enio; Paula, Ivan Antonio Machado de; Palma, Honório; Branco, João Nelson Rodrigues. A new surgical approach for treating dilated cardiomyopathy with mitral regurgitation. Arquivos Brasileiros de Cardiologia, v. 74, n. 2, p. 135-140, set. 2000.

Formato de Documento Eletrônico (APA)

Buffolo, E., Paula, I. A. M. , Palma, H., & Branco, J. N. R. (2000). A new surgical approach for treating dilated cardiomyopathy with mitral regurgitation. Arquivos Brasileiros de Cardiologia, 74(2), 135-140.

Formato de Documento Eletrônico (ISO)

Buffolo, Enio and Paula, Ivan Antonio Machado de and Palma, Honório and Branco, João Nelson Rodrigues. A new surgical approach for treating dilated cardiomyopathy with mitral regurgitation. Arquivos Brasileiros de Cardiologia [online]. 2000, vol. 74, n. 2, [citado 2026-11-15], pp. 135-140. Disponível em: <https://journals.cardiol.br/article/a-new-surgical-approach-for-treating-dilated-cardiomyopathy-with-mitral-regurgitation-2/>. ISSN 0066-782X

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Coutinho MSSA, Nakamae FJD, Menezes ME. Chlamydia pneumoniae and atherosclerosis. Identification of bacterial DNA in the arterial wall. Arquivos Brasileiros de Cardiologia 2000;74(2):124-8.

Formato de Documento Eletrônico (ABNT)

Coutinho, Mário Sérgio Soares de Azeredo; Nakamae, Fernando Joo Daniel; Menezes, Maria Elizabeth. Chlamydia pneumoniae and atherosclerosis. Identification of bacterial DNA in the arterial wall. Arquivos Brasileiros de Cardiologia, v. 74, n. 2, p. 124-128, set. 2000.

Formato de Documento Eletrônico (APA)

Coutinho, M. S. S. A., Nakamae, F. J. D., & Menezes, M. E. (2000). Chlamydia pneumoniae and atherosclerosis. Identification of bacterial DNA in the arterial wall. Arquivos Brasileiros de Cardiologia, 74(2), 124-128.

Formato de Documento Eletrônico (ISO)

Coutinho, Mário Sérgio Soares de Azeredo and Nakamae, Fernando Joo Daniel and Menezes, Maria Elizabeth. Chlamydia pneumoniae and atherosclerosis. Identification of bacterial DNA in the arterial wall. Arquivos Brasileiros de Cardiologia [online]. 2000, vol. 74, n. 2, [citado 2026-11-15], pp. 124-128. Disponível em: <https://journals.cardiol.br/article/chlamydia-pneumoniae-and-atherosclerosis-identification-of-bacterial-dna-in-the-arterial-wall-2/>. ISSN 0066-782X

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