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  2. Keyword: Thromboembolism/prevention and control
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Editorial

The Double-Orifice Technique in Mitral Valve Repair: 35 Years of History

Pablo Maria Alberto Pomerantzeff et al. Carlos Manuel de Almeida Brandão Arlindo Riso Fabio Biscegli Jatene

The advantages of mitral valve repair are lower morbidity and mortality, reduced risk of thromboembolism and endocarditis, improved survival, and better preservation of left ventricular function. The most common cause of degenerative mitral regurgitation is a myxomatous valve with segmental prolapse of the posterior leaflet, a lesion that can be corrected by classical techniques such as quadrangular resection, but other lesions may require more complex surgical techniques, for instance, correction of anterior leaflet prolapse or Barlow disease. Mitral valve repair in rheumatic patients is still a challenge.

In December 1984, Adib Domingos Jatene MD, PhD performed the first “duplication of the mitral orifice”, in a female patient with mitral insufficiency due to rupture of anterior leaflet chordae (). The technique restored mitral competence by anchoring the free edge of the prolapsing leaflets to the corresponding free edge of the opposing leaflet with a 5-0 polypropylene stitch reinforced with pledgets. The patient presented good immediate and long-term evolution.

[…]

  • Endocarditis/prevention and control
  • Heart Valve Diseases/surgery
  • Mitral Valve/surgery
  • Morbidity and Mortality
  • Thromboembolism/prevention and control
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Creative Commons Attribution (CC BY) Creative Commons license
20/09/2021 DOI: 10.36660/abc.20210067
IJCS
Editorial

Challenges for Anticoagulation in Atrial Fibrillation

Ana Inês da Costa Bronchtein

Atrial fibrillation (AF) is the most prevalent arrhythmia in the world. It is considered a current epidemic and one of the main causes of ischemic stroke, usually with severe and debilitating conditions, and is responsible for systemic cardioembolic phenomena, increased number of cases of congestive heart failure (CHF), cognitive impairment related to silent embolic phenomena, and increased overall mortality in affected patients.

Vitamin K antagonists (VKA) represented in the vast majority of studies with warfarin have been widely used for many years; however, they have complex adherence due to several factors, including the need for frequent INR monitoring, regular dose adjustments for maintaining a suitable time in therapeutic range (TTR) (>= 70%) and interactions with a number of drugs and foods, which contributed to its ever decreasing use. Direct-acting anticoagulants (DACs), represented by dabigatran, rivaroxaban, apixaban and, more recently, edoxaban, offer an alternative to VKA, without the disadvantages presented by the latter.

[…]

  • Anticoagulants
  • Atrial Fibrillation
  • Brain Ischemia
  • Thromboembolism/prevention and control
  • Vitamin K
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Creative Commons Attribution (CC BY) Creative Commons license
17/02/2020 DOI: 10.36660/ijcs.20190003 Views 2

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Pomerantzeff PMA, Brandão CMA, Riso A, Jatene FB. The Double-Orifice Technique in Mitral Valve Repair: 35 Years of History. Arquivos Brasileiros de Cardiologia 2021;117(3):424-5.

Electronic Document Format (ABNT)

Pomerantzeff, Pablo Maria Alberto; Brandão, Carlos Manuel de Almeida; Riso, Arlindo; Jatene, Fabio Biscegli. The Double-Orifice Technique in Mitral Valve Repair: 35 Years of History. Arquivos Brasileiros de Cardiologia, v. 117, n. 3, p. 424-425, Sep. 2021.

Electronic Document Format (APA)

Pomerantzeff, P. M. A., Brandão, C. M. A., Riso, A., & Jatene, F. B. (2021). The Double-Orifice Technique in Mitral Valve Repair: 35 Years of History. Arquivos Brasileiros de Cardiologia, 117(3), 424-425.

Electronic Document Format (ISO)

Pomerantzeff, Pablo Maria Alberto and Brandão, Carlos Manuel de Almeida and Riso, Arlindo and Jatene, Fabio Biscegli. The Double-Orifice Technique in Mitral Valve Repair: 35 Years of History. Arquivos Brasileiros de Cardiologia [online]. 2021, vol. 117, n. 3, [cited 2026-10-14], pp. 424-425. Available from: <https://journals.cardiol.br/en/article/the-double-orifice-technique-in-mitral-valve-repair-35-years-of-history/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Bronchtein AIC. Challenges for Anticoagulation in Atrial Fibrillation. International Journal of Cardiovascular Sciences 2020;33(1):65-7.

Electronic Document Format (ABNT)

Bronchtein, Ana Inês da Costa. Challenges for Anticoagulation in Atrial Fibrillation. International Journal of Cardiovascular Sciences, v. 33, n. 1, p. 65-67, Feb. 2020.

Electronic Document Format (APA)

Bronchtein, A. I. C. (2020). Challenges for Anticoagulation in Atrial Fibrillation. International Journal of Cardiovascular Sciences, 33(1), 65-67.

Electronic Document Format (ISO)

Bronchtein, Ana Inês da Costa. Challenges for Anticoagulation in Atrial Fibrillation. International Journal of Cardiovascular Sciences [online]. 2020, vol. 33, n. 1, [cited 2026-10-14], pp. 65-67. Available from: <https://journals.cardiol.br/en/article/challenges-for-anticoagulation-in-atrial-fibrillation/>. ISSN 2359-4802

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