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  2. Keyword: Cross-sectional Study
Evaluation of Antibiotic Prophylaxis Prescriptions for Infectious Endocarditis Before Oral Procedures Between Cardiologists and Dentists
IJCS
Original Article

Evaluation of Antibiotic Prophylaxis Prescriptions for Infectious Endocarditis Before Oral Procedures Between Cardiologists and Dentists

Mariana Mattos Brandão et al. Luisa Latado Lívia Brito Oliveira Viviane Almeida Sarmento Adriana Lopes Latado

Abstract

Background

Infective endocarditis (IE) is a serious disease with a high mortality rate. Antibiotic prophylaxis for bacterial endocarditis before invasive procedures has been recommended in patients with predisposing cardiac conditions since 1960, but contemporary guidelines worldwide have proposed changes.

Objective

To evaluate the knowledge and pattern of prescription by cardiologists and dentists regarding antibiotic prophylaxis for bacterial endocarditis before risky oral procedures.

Methods

This is an observational and cross-sectional study. Data were obtained from an online questionnaire, sent to cardiologists and dentists linked to specialty societies, in the first semester of 2021. Data analysis was performed using descriptive statistics, and comparisons between variables were done in an exploratory approach. The significance level adopted was 5%.

Results

From 613 responders, 82.5% of cardiologists and 79.5% of dentists reported prescribing antibiotic prophylaxis for patients at high and moderate risk for IE. Of dental procedures capable of generating bacteremia, all were correctly identified by more than 50.0% of the sample. As for the habits of daily living, flossing and toothbrushing had almost 50.0% of correct answers, chewing had only 17.3%, and 40.9% reported that none of the actions presented a risk of bacteremia. When comparing variables, the correct prescription of amoxicillin (2 g, 30–60 minutes before the procedure) was more prevalent among cardiologists and in responders with less than 20 years of graduation (p<0.01).

Conclusion

In the present study, the prescription of antibiotic prophylaxis for IE were frequent for high- and moderate-risk patients, before oral/dental procedures. Partial knowledge was found about endocarditis, which highlights the need for continuous medical/dental education.

  • Antibiotic Prophylaxis
  • Bacterial Endocarditis
  • Cross-sectional Study
  • Oral Surgical Procedures
  • Prescriptions
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Creative Commons Attribution (CC BY) Creative Commons license
22/12/2023 DOI: 10.36660/ijcs.20230034 Views 1
IJCS
Original Article

Analysis of Adherence to Antihypertensive Drug Treatment in an Argentinean Cohort

Walter Gaston Espeche et al. Rodrigo Sabio Alejandro Diaz Roberto Parodi … Carlos Enrique Leiva Sisnieguez Roberto Antonio Flores Silvia Poppe Javier Altube Diego Grimaldi Martin Rogelio Salazar

Abstract

Background

Adherence to antihypertensive medication is a major challenge in the management of hypertension, and non-adherence is an important barrier to effective management of hypertension.

Objectives

To determine the adherence rate to hypertensive drug treatment and the factors that influence non-adherence in a cohort of the Argentinean population.

Methods

A multicenter cross-sectional study was conducted in eight cities of Argentina. Consecutive hypertensive patients seen in general practice offices, receiving pharmacological treatment for at least six months were included. Blood pressure measurements were performed by physicians during the patient visit. The level of adherence was assessed using the Morisky questionnaire, and patients were divided into non-adherent and adherent. Continuous variables were compared using independent t-test. Categorical variables were compared using the χ2 test. To identify the variables independently associated with non-adherence, a forward stepwise binary regression logistic model was performed, and the results expressed as odds ratio (OR) with 95% of confidence interval. All tests were two-tailed, and p-values < 0.05 were considered statistically significant.

Results

A total of 852 individuals (52% women, 62 ± 13 years) were included. The main reason for lack of adherence was forgetfulness of medication intake and errors in the time of intake (~ 40% in both). Individuals with more cardiovascular risk factors (smoking, diabetes, dyslipidemia and previous cardiovascular events) had lower adherence to antihypertensive treatment, and considerably younger (~ five years younger).

Conclusions

Adherence rate to antihypertensive drug treatment in our study group was higher than the one reported in previous studies, and the main reason for non-adherence was forgetfulness of medication intake. (Int J Cardiovasc Sci. 2020; 33(3):272-277)

  • antihypertensive agents
  • Cross-sectional Study
  • Hypertension/epidemiology
  • Risk Factors
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Creative Commons Attribution (CC BY) Creative Commons license
29/05/2020 DOI: 10.36660/ijcs.20190069 Views 1

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Brandão MM, Latado L, Oliveira LB, Sarmento VA, Latado AL. Evaluation of Antibiotic Prophylaxis Prescriptions for Infectious Endocarditis Before Oral Procedures Between Cardiologists and Dentists. International Journal of Cardiovascular Sciences 2023;36:e20230034.

Electronic Document Format (ABNT)

Brandão, Mariana Mattos; Latado, Luisa; Oliveira, Lívia Brito; Sarmento, Viviane Almeida; Latado, Adriana Lopes. Evaluation of Antibiotic Prophylaxis Prescriptions for Infectious Endocarditis Before Oral Procedures Between Cardiologists and Dentists. International Journal of Cardiovascular Sciences, v. 36, e20230034, Dec. 2023.

Electronic Document Format (APA)

Brandão, M. M., Latado, L., Oliveira, L. B., Sarmento, V. A., & Latado, A. L. (2023). Evaluation of Antibiotic Prophylaxis Prescriptions for Infectious Endocarditis Before Oral Procedures Between Cardiologists and Dentists. International Journal of Cardiovascular Sciences, 36, e20230034.

Electronic Document Format (ISO)

Brandão, Mariana Mattos and Latado, Luisa and Oliveira, Lívia Brito and Sarmento, Viviane Almeida and Latado, Adriana Lopes. Evaluation of Antibiotic Prophylaxis Prescriptions for Infectious Endocarditis Before Oral Procedures Between Cardiologists and Dentists. International Journal of Cardiovascular Sciences [online]. 2023, vol. 36, [cited 2026-10-14], e20230034. Available from: <https://journals.cardiol.br/en/article/evaluation-of-antibiotic-prophylaxis-prescriptions-for-infectious-endocarditis-before-oral-procedures-between-cardiologists-and-dentists/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Espeche WG, Sabio R, Diaz A, Parodi R, Sisnieguez CEL, Flores RA, Poppe S, et al. Analysis of Adherence to Antihypertensive Drug Treatment in an Argentinean Cohort. International Journal of Cardiovascular Sciences 2020;33(3):272-7.

Electronic Document Format (ABNT)

Espeche, Walter Gaston; Sabio, Rodrigo; Diaz, Alejandro; Parodi, Roberto; Sisnieguez, Carlos Enrique Leiva; Flores, Roberto Antonio; Poppe, Silvia; Altube, Javier; Grimaldi, Diego; Salazar, Martin Rogelio. Analysis of Adherence to Antihypertensive Drug Treatment in an Argentinean Cohort. International Journal of Cardiovascular Sciences, v. 33, n. 3, p. 272-277, May. 2020.

Electronic Document Format (APA)

Espeche, W. G., Sabio, R., Diaz, A., Parodi, R., Sisnieguez, C. E. L., Flores, R. A., Poppe, S., Altube, J., Grimaldi, D., & Salazar, M. R. (2020). Analysis of Adherence to Antihypertensive Drug Treatment in an Argentinean Cohort. International Journal of Cardiovascular Sciences, 33(3), 272-277.

Electronic Document Format (ISO)

Espeche, Walter Gaston and Sabio, Rodrigo and Diaz, Alejandro and Parodi, Roberto and Sisnieguez, Carlos Enrique Leiva and Flores, Roberto Antonio and Poppe, Silvia and Altube, Javier and Grimaldi, Diego and Salazar, Martin Rogelio. Analysis of Adherence to Antihypertensive Drug Treatment in an Argentinean Cohort. International Journal of Cardiovascular Sciences [online]. 2020, vol. 33, n. 3, [cited 2026-10-14], pp. 272-277. Available from: <https://journals.cardiol.br/en/article/analysis-of-adherence-to-antihypertensive-drug-treatment-in-an-argentinean-cohort/>. ISSN 2359-4802

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