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  2. Keyword: Bacterial Endocarditis
Figure 1
ABC
Research Letter

Whipple’s Disease as a Differential Diagnosis of Blood Culture-Negative Endocarditis: A Case Report

Carolina Kuchenbecker Soares et al. Rafaela Clara Resende da Silva Geraldo Brasileiro Filho Claudio Leo Gelape … Jésus Faria Rosa Júnior Luiz Guilherme Passaglia

Abstract

Whipple’s endocarditis is a rare infectious condition caused by the bacterium Tropheryma whipplei. Although its systemic form is the most widely recognized, the infection exhibits a broad spectrum of extraintestinal manifestations, with blood culture-negative infective endocarditis being the most common form of cardiac involvement. The case presented in this study underscores the importance of clinical investigation for accurate diagnosis and the application of appropriate treatment.

  • Bacterial Endocarditis
  • Stroke
  • Whipple Disease
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Creative Commons Attribution (CC BY) Creative Commons license
18/08/2025 DOI: 10.36660/abc.20240207i Views 1
Evaluation of Antibiotic Prophylaxis Prescriptions for Infectious Endocarditis Before Oral Procedures Between Cardiologists and Dentists
IJCS
Original Article

Evaluation of Antibiotic Prophylaxis Prescriptions for Infectious Endocarditis Before Oral Procedures Between Cardiologists and Dentists

Mariana Mattos Brandão et al. Luisa Latado Lívia Brito Oliveira Viviane Almeida Sarmento Adriana Lopes Latado

Abstract

Background

Infective endocarditis (IE) is a serious disease with a high mortality rate. Antibiotic prophylaxis for bacterial endocarditis before invasive procedures has been recommended in patients with predisposing cardiac conditions since 1960, but contemporary guidelines worldwide have proposed changes.

Objective

To evaluate the knowledge and pattern of prescription by cardiologists and dentists regarding antibiotic prophylaxis for bacterial endocarditis before risky oral procedures.

Methods

This is an observational and cross-sectional study. Data were obtained from an online questionnaire, sent to cardiologists and dentists linked to specialty societies, in the first semester of 2021. Data analysis was performed using descriptive statistics, and comparisons between variables were done in an exploratory approach. The significance level adopted was 5%.

Results

From 613 responders, 82.5% of cardiologists and 79.5% of dentists reported prescribing antibiotic prophylaxis for patients at high and moderate risk for IE. Of dental procedures capable of generating bacteremia, all were correctly identified by more than 50.0% of the sample. As for the habits of daily living, flossing and toothbrushing had almost 50.0% of correct answers, chewing had only 17.3%, and 40.9% reported that none of the actions presented a risk of bacteremia. When comparing variables, the correct prescription of amoxicillin (2 g, 30–60 minutes before the procedure) was more prevalent among cardiologists and in responders with less than 20 years of graduation (p<0.01).

Conclusion

In the present study, the prescription of antibiotic prophylaxis for IE were frequent for high- and moderate-risk patients, before oral/dental procedures. Partial knowledge was found about endocarditis, which highlights the need for continuous medical/dental education.

  • Antibiotic Prophylaxis
  • Bacterial Endocarditis
  • Cross-sectional Study
  • Oral Surgical Procedures
  • Prescriptions
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Creative Commons Attribution (CC BY) Creative Commons license
22/12/2023 DOI: 10.36660/ijcs.20230034 Views 1
Infectious endocarditis due to Streptococcus bovis in a patient with colon carcinoma
ABC
Case Report

Infectious endocarditis due to Streptococcus bovis in a patient with colon carcinoma

Alexandre Maulaz Barcelos et al. Marco Antônio Teixeira Lidianny Silva Alves Marcelo Antunes Vieira … Marcus Lima Bedim Noely A. Ribeiro

We report the case of a 66 year-old female patient with infectious endocarditis due to Streptococcus bovis and adenocarcinoma of the colon that developed acute aortic insufficiency. She was submitted to aortic valve replacement surgery and later to tumor resection (right hemicolectomy). It is important to emphasize the need for complementing the study of the colon, even in asymptomatic individuals, when infectious endocarditis due to S. bovis is diagnosed.

  • adenocarcinoma
  • Aortic Valve Insufficiency
  • Bacterial Endocarditis
  • Streptococcus bovis
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Creative Commons Attribution (CC BY) Creative Commons license
13/10/2010 DOI: 10.1590/S0066-782X2010001300023 Views 1
ABC
Original Article

A study of infectious endocarditis in Ribeirão Preto, SP – Brazil. Analysis of cases occurring between 1992 and 1997

Everaldo Ruiz Jr et al. Tarciso Schirmbeck Luiz Tadeu Moraes Figueiredo

OBJECTIVE: To analyze the epidemiology, diagnosis, clinical aspects causes and evolution of infectious endocarditis. METHODS: The patients analyzed were treated at the University Hospital of the Faculdade de Medicina of Ribeirão Preto-USP and had a diagnosis of infectious endocarditis defined by Duke’s criteria, which classifies infectious endocarditis as native, prosthetic valve or that occurring in intravenous drug users. RESULTS: One hundred and eighty episodes of infectious endocarditis in 168 patients were observed. Echocardiograms in 132 (73.3%) provided a diagnosis of infectious endocarditis in 111 (84%) patients; mitral valves were affected in 55 (30.5%), tricuspid valves in 30 (16.6%) and the aortic valve in 28 (15.5%) patients. Hemocultures were performed in 148 (93.8%) episodes of IE. The most commonly isolated infectious organisms were Staphylococcus aureus in 46 (27.2%) patients and Streptococcus viridans in 27 (15.9%). Complications occurred in 116 (64.4%) patients and 73 (40.5%) of the patients died. CONCLUSION: The general profile of the observed infectious endocarditis was similar to that reported in studies performed in other countries and included users of intravenous drugs. The high degree of mortality observed is not compatible with progress in diagnosis and treatment of infectious endocarditis and is probably due to the absence of diagnostic suspicion. The high frequency of fatal cases of septicemia (45.1% of deaths) in the patients studied indicates that unnoticed cases of infectious endocarditis had only been diagnosed at necropsy.

  • Bacterial Endocarditis
  • endocarditis in Brazil
  • infectious endocarditis
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Creative Commons Attribution (CC BY) Creative Commons license
08/01/2002 DOI: 10.1590/S0066-782X2000000300004 Views 2

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Soares CK, Silva RCR, Brasileiro Filho G, Gelape CL, Rosa Júnior JF, Passaglia LG. Whipple’s Disease as a Differential Diagnosis of Blood Culture-Negative Endocarditis: A Case Report. Arquivos Brasileiros de Cardiologia 2025;122(7):e20240207.

Electronic Document Format (ABNT)

Soares, Carolina Kuchenbecker; Silva, Rafaela Clara Resende da; Brasileiro Filho, Geraldo; Gelape, Claudio Leo; Rosa Júnior, Jésus Faria; Passaglia, Luiz Guilherme. Whipple’s Disease as a Differential Diagnosis of Blood Culture-Negative Endocarditis: A Case Report. Arquivos Brasileiros de Cardiologia, v. 122, n. 7, e20240207, Aug. 2025.

Electronic Document Format (APA)

Soares, C. K., Silva, R. C. R. , Brasileiro Filho, G., Gelape, C. L., Rosa Júnior, J. F., & Passaglia, L. G. (2025). Whipple’s Disease as a Differential Diagnosis of Blood Culture-Negative Endocarditis: A Case Report. Arquivos Brasileiros de Cardiologia, 122(7), e20240207.

Electronic Document Format (ISO)

Soares, Carolina Kuchenbecker and Silva, Rafaela Clara Resende da and Brasileiro Filho, Geraldo and Gelape, Claudio Leo and Rosa Júnior, Jésus Faria and Passaglia, Luiz Guilherme. Whipple’s Disease as a Differential Diagnosis of Blood Culture-Negative Endocarditis: A Case Report. Arquivos Brasileiros de Cardiologia [online]. 2025, vol. 122, n. 7, [cited 2026-10-14], e20240207. Available from: <https://journals.cardiol.br/en/article/whipples-disease-as-a-differential-diagnosis-of-blood-culture-negative-endocarditis-a-case-report/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Brandão MM, Latado L, Oliveira LB, Sarmento VA, Latado AL. Evaluation of Antibiotic Prophylaxis Prescriptions for Infectious Endocarditis Before Oral Procedures Between Cardiologists and Dentists. International Journal of Cardiovascular Sciences 2023;36:e20230034.

Electronic Document Format (ABNT)

Brandão, Mariana Mattos; Latado, Luisa; Oliveira, Lívia Brito; Sarmento, Viviane Almeida; Latado, Adriana Lopes. Evaluation of Antibiotic Prophylaxis Prescriptions for Infectious Endocarditis Before Oral Procedures Between Cardiologists and Dentists. International Journal of Cardiovascular Sciences, v. 36, e20230034, Dec. 2023.

Electronic Document Format (APA)

Brandão, M. M., Latado, L., Oliveira, L. B., Sarmento, V. A., & Latado, A. L. (2023). Evaluation of Antibiotic Prophylaxis Prescriptions for Infectious Endocarditis Before Oral Procedures Between Cardiologists and Dentists. International Journal of Cardiovascular Sciences, 36, e20230034.

Electronic Document Format (ISO)

Brandão, Mariana Mattos and Latado, Luisa and Oliveira, Lívia Brito and Sarmento, Viviane Almeida and Latado, Adriana Lopes. Evaluation of Antibiotic Prophylaxis Prescriptions for Infectious Endocarditis Before Oral Procedures Between Cardiologists and Dentists. International Journal of Cardiovascular Sciences [online]. 2023, vol. 36, [cited 2026-10-14], e20230034. Available from: <https://journals.cardiol.br/en/article/evaluation-of-antibiotic-prophylaxis-prescriptions-for-infectious-endocarditis-before-oral-procedures-between-cardiologists-and-dentists/>. ISSN 2359-4802

EndNote RIS

Electronic Document Format (Vancouver)

Barcelos AM, Teixeira MA, Alves LS, Vieira MA, Bedim ML, Ribeiro NA. Infectious endocarditis due to Streptococcus bovis in a patient with colon carcinoma. Arquivos Brasileiros de Cardiologia 2010;95(3):e88-90.

Electronic Document Format (ABNT)

Barcelos, Alexandre Maulaz; Teixeira, Marco Antônio; Alves, Lidianny Silva; Vieira, Marcelo Antunes; Bedim, Marcus Lima; Ribeiro, Noely A.. Infectious endocarditis due to Streptococcus bovis in a patient with colon carcinoma. Arquivos Brasileiros de Cardiologia, v. 95, n. 3, p. e88-e90, Oct. 2010.

Electronic Document Format (APA)

Barcelos, A. M., Teixeira, M. A., Alves, L. S., Vieira, M. A., Bedim, M. L., & Ribeiro, N. A. (2010). Infectious endocarditis due to Streptococcus bovis in a patient with colon carcinoma. Arquivos Brasileiros de Cardiologia, 95(3), e88-e90.

Electronic Document Format (ISO)

Barcelos, Alexandre Maulaz and Teixeira, Marco Antônio and Alves, Lidianny Silva and Vieira, Marcelo Antunes and Bedim, Marcus Lima and Ribeiro, Noely A.. Infectious endocarditis due to Streptococcus bovis in a patient with colon carcinoma. Arquivos Brasileiros de Cardiologia [online]. 2010, vol. 95, n. 3, [cited 2026-10-14], pp. e88-e90. Available from: <https://journals.cardiol.br/en/article/infectious-endocarditis-due-to-streptococcus-bovis-in-a-patient-with-colon-carcinoma/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Ruiz Jr E, Schirmbeck T, Figueiredo LTM. A study of infectious endocarditis in Ribeirão Preto, SP – Brazil. Analysis of cases occurring between 1992 and 1997. Arquivos Brasileiros de Cardiologia 2002;74(3):225-31.

Electronic Document Format (ABNT)

Ruiz Jr, Everaldo; Schirmbeck, Tarciso; Figueiredo, Luiz Tadeu Moraes. A study of infectious endocarditis in Ribeirão Preto, SP – Brazil. Analysis of cases occurring between 1992 and 1997. Arquivos Brasileiros de Cardiologia, v. 74, n. 3, p. 225-231, Jan. 2002.

Electronic Document Format (APA)

Ruiz Jr, E., Schirmbeck, T., & Figueiredo, L. T. M. (2002). A study of infectious endocarditis in Ribeirão Preto, SP – Brazil. Analysis of cases occurring between 1992 and 1997. Arquivos Brasileiros de Cardiologia, 74(3), 225-231.

Electronic Document Format (ISO)

Ruiz Jr, Everaldo and Schirmbeck, Tarciso and Figueiredo, Luiz Tadeu Moraes. A study of infectious endocarditis in Ribeirão Preto, SP – Brazil. Analysis of cases occurring between 1992 and 1997. Arquivos Brasileiros de Cardiologia [online]. 2002, vol. 74, n. 3, [cited 2026-10-14], pp. 225-231. Available from: <https://journals.cardiol.br/en/article/a-study-of-infectious-endocarditis-in-ribeirao-preto-sp-brazil-analysis-of-cases-occurring-between-1992-and-1997/>. ISSN 0066-782X

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