Chagas´ – ABC CARDIOL

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Letter to the Editor

The Challenge of Effective Secondary Stroke Prophylaxis in Chagas Patients

The recent update on the guideline for the management of cardiomyopathy in Chagas disease brings several significant improvements. The evidence on etiological stroke investigation, management of secondary prophylaxis, and overall epidemiology are all of vital importance for clinicians to improve treatment for these patients.

One concern that arises from the guideline pertains to the indication of oral anticoagulation, particularly the suggestion that any previous ischemic stroke would warrant such intervention.

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Artigo Original

Myocardial dysfunction in chagasic patients with no apparent heart disease

Airandes de Sousa Pinto et al. Braulio Muzzi Ribeiro de Oliveira Fernando Antonio Botoni Antonio Luiz Pinho Ribeiro Manoel Otavio da Costa Rocha

BACKGROUND: The Tei index simultaneously evaluates the ventricular systolic and diastolic functions. It has a good correlation with hemodynamic data and has enabled the detection of initial ventricular function alterations of different etiologies. OBJECTIVE: To study initial biventricular function alterations in chagasic patients with no apparent heart disease, using the Tei index. METHODS: Forty eight individuals were evaluated. Group 1 was comprised of 25 patients diagnosed with Chagas´ disease with no apparent heart disease and normal echocardiogram; group 2 was comprised of 23 healthy individuals with negative serological tests for Chagas´ disease. RESULTS: The Tei index was significantly higher in the group of chagasic patients with no apparent heart disease when compared to that of the control group: left ventricular Tei index (0.48 ± 0.11 vs. 0.36 ± 0.06, p < 0.001) , right ventricular Tei index (0.34 ± 0.10 vs. 0.26 ± 0.07, p = 0.001). The left and right ventricular Tei indexes were considered abnormal in 48% and 28% of the chagasic patients, respectively. CONCLUSION: Chagasic patients with no apparent heart disease present early alterations of the right and left ventricles.

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The Challenge of Effective Secondary Stroke Prophylaxis in Chagas Patients

Myocardial dysfunction in chagasic patients with no apparent heart disease

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Electronic Document Format (Vancouver)

Electronic Document Format (ABNT)

Electronic Document Format (APA)

Electronic Document Format (ISO)