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Família ABC

  • Família ABC
  • Arquivos Brasileiros de Cardiologia
  • International Journal of Cardiovascular Sciences
  • ABC Heart Failure & Cardiomyopathy
  • ABC Imagem Cardiovascular
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  2. Palavra-chave: Pulmonary Artery
IJCS
Case Report

Left Pulmonary Artery Aneurysm in an Adult Patient With Uncorrected Tetralogy of Fallot and Patent Ductus Arteriosus: A Case Report

Miguel Bernardino Antunes Vicente et al. Elsa Fernandes Roger Dopico Luis Mariano … Odete Mingas Domingos Ramos Lino Gonçalves

Abstract

The authors describe a case of an infrequent triple association: left pulmonary artery aneurysm (PAA), uncorrected tetralogy of Fallot (TOF) and patent ductus arteriosus (PDA), diagnosed in a 45-year-old adult patient during a check-up. The patient refused to undergo surgery and is currently being followed clinically.

  • Aneurysm
  • Pulmonary Artery
  • Tetralogy of Fallot
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Creative Commons Attribution (CC BY) Creative Commons license
16/06/2025 DOI: 10.36660/ijcs.20240249
IJCS
Original Article

The Relationship between Basal Serum Lipoprotein(a) Levels and the Pulmonary Artery to Ascending Aorta Ratio in COVID-19 Survivors

Uğur Küçük et al. Bahadır Kırılmaz

Abstract

Background:

Coronavirus disease (COVID-19) can cause permanent damage to vascular structures by directly or indirectly affecting the cardiopulmonary system. Lipoprotein(a) [Lp(a)] is an important identified risk factor for vascular endothelial cell dysfunction.

Objective:

The aim of this study was to reveal the relationship between Lp(a) levels measured at the time of COVID-19 diagnosis and the pulmonary artery (PA) to the ascending aorta (Ao) ratio (PA:Ao ratio) in survivors evaluated by transthoracic echocardiography (TTE).

Methods:

The study sample consisted of 100 patients who recovered from COVID-19 in the past 3 to 6 months. The relationship between the change in the PA:Ao ratio (ΔPA:Ao) and the Lp(a) levels measured at the time of diagnosis was evaluated. Diameter measurements at baseline and follow-up were evaluated with TTE.

Results:

A significant increase was found in PA, Ao, and epicardial adipose tissue (EAT) thickness in TTE (p< 0.001 for all). There was a weak correlation between D-dimer and high-sensitivity cardiac troponin measured at the time of diagnosis and ΔPA:Ao and ΔEAT in survivors. However, a positive and strong correlation was observed between Lp(a) levels and ΔPa:Ao (r = 0.628, p< 0.001) and ΔEAT (r = 0.633, p< 0.001).

Conclusion:

There may be dysfunction in vascular structures due to COVID-19. For the first time in the literature, a strong correlation was shown between the Lp(a) levels measured at the time of diagnosis and ΔPA:Ao and ΔEAT values in patients with COVID-19.

  • Aorta, Thoracic
  • COVID-19
  • Echocardiography
  • Lipoprotein(a)
  • Pulmonary Artery
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Creative Commons Attribution (CC BY) Creative Commons license
15/09/2023 DOI: 10.36660/ijcs.20220208

Como citar este artigo

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Vicente MBA, Fernandes E, Dopico R, Mariano L, Mingas O, Ramos D, Gonçalves L, et al. Left Pulmonary Artery Aneurysm in an Adult Patient With Uncorrected Tetralogy of Fallot and Patent Ductus Arteriosus: A Case Report. International Journal of Cardiovascular Sciences 2025;38:e20240249.

Formato de Documento Eletrônico (ABNT)

Vicente, Miguel Bernardino Antunes; Fernandes, Elsa; Dopico, Roger; Mariano, Luis; Mingas, Odete; Ramos, Domingos; Gonçalves, Lino. Left Pulmonary Artery Aneurysm in an Adult Patient With Uncorrected Tetralogy of Fallot and Patent Ductus Arteriosus: A Case Report. International Journal of Cardiovascular Sciences, v. 38, e20240249, jun. 2025.

Formato de Documento Eletrônico (APA)

Vicente, M. B. A., Fernandes, E., Dopico, R., Mariano, L., Mingas, O., Ramos, D., & Gonçalves, L. (2025). Left Pulmonary Artery Aneurysm in an Adult Patient With Uncorrected Tetralogy of Fallot and Patent Ductus Arteriosus: A Case Report. International Journal of Cardiovascular Sciences, 38, e20240249.

Formato de Documento Eletrônico (ISO)

Vicente, Miguel Bernardino Antunes and Fernandes, Elsa and Dopico, Roger and Mariano, Luis and Mingas, Odete and Ramos, Domingos and Gonçalves, Lino. Left Pulmonary Artery Aneurysm in an Adult Patient With Uncorrected Tetralogy of Fallot and Patent Ductus Arteriosus: A Case Report. International Journal of Cardiovascular Sciences [online]. 2025, vol. 38, [citado 2026-10-14], e20240249. Disponível em: <https://journals.cardiol.br/article/left-pulmonary-artery-aneurysm-in-an-adult-patient-with-uncorrected-tetralogy-of-fallot-and-patent-ductus-arteriosus-a-case-report-2/>. ISSN 2359-4802

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Küçük U, Kırılmaz B. The Relationship between Basal Serum Lipoprotein(a) Levels and the Pulmonary Artery to Ascending Aorta Ratio in COVID-19 Survivors. International Journal of Cardiovascular Sciences 2023;36:e20220208.

Formato de Documento Eletrônico (ABNT)

Küçük, Uğur; Kırılmaz, Bahadır. The Relationship between Basal Serum Lipoprotein(a) Levels and the Pulmonary Artery to Ascending Aorta Ratio in COVID-19 Survivors. International Journal of Cardiovascular Sciences, v. 36, e20220208, set. 2023.

Formato de Documento Eletrônico (APA)

Küçük, U., & Kırılmaz, B. (2023). The Relationship between Basal Serum Lipoprotein(a) Levels and the Pulmonary Artery to Ascending Aorta Ratio in COVID-19 Survivors. International Journal of Cardiovascular Sciences, 36, e20220208.

Formato de Documento Eletrônico (ISO)

Küçük, Uğur and Kırılmaz, Bahadır. The Relationship between Basal Serum Lipoprotein(a) Levels and the Pulmonary Artery to Ascending Aorta Ratio in COVID-19 Survivors. International Journal of Cardiovascular Sciences [online]. 2023, vol. 36, [citado 2026-10-14], e20220208. Disponível em: <https://journals.cardiol.br/article/the-relationship-between-basal-serum-lipoproteina-levels-and-the-pulmonary-artery-to-ascending-aorta-ratio-in-covid-19-survivors-2/>. ISSN 2359-4802

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