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  2. Palavra-chave: Obesity, Abdominal
IJCS
Original Article

Analysis of the Influence of Abdominal Obesity on Systemic Arterial Hypertension and on the Lipid Profile on Cardiometabolic Risk Stratification in Adult Women

Iury Matheus Lima Cavalcanti et al. Cristian Rodrigues do Nascimento Pedro Pereira Tenório Tiago Ferreira da Silva Araújo

Abstract

Background:

Obesity is a public health problem and has been associated with the development of metabolic disorders that have a strong relationship with the onset of cardiovascular diseases (CVD).

Objective:

The objective was to analyze the influence of abdominal obesity (AO) on systemic arterial hypertension (SAH) and on the lipid profile in cardiovascular risk stratification in adult women.

Methods:

Altogether, 91 women participated in the research. Lifestyle information was collected, in addition to the analysis of clinical measures of cardiovascular risk and biochemical parameters. Unpaired Student’s t-test, logistic regression, and Pearson’s correlation were performed for data analysis, with a value of p <0.05 considered significant.

Results:

The prevalence of AO was 62.6%. Logistic regression showed that AO increased the chance of developing SAH by 2.9-fold. The same behavior was observed in the TG/HDL-c lipid ratio (3.93 ± 0.3 vs. 2.16 ± 0.2), representing an 82% increase in obese women. The present study also demonstrated that the best anthropometric parameter to analyze cardiovascular risk in the studied population was the waist/height ratio (AUC = 0.707).

Conclusions:

It can therefore be concluded that AO plays a significant role in the development of SAH and changes in lipid values that predict increased cardiovascular risk, configuring a strong influence factor for CVD.

  • Adult
  • cardiovascular diseases
  • Hyperlipidemias
  • Hypertension
  • Lipidic Metabolism
  • Metabolic Syndrome
  • Obesity, Abdominal
  • Risk Stratification
  • Women
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Creative Commons Attribution (CC BY) Creative Commons license
01/04/2022 DOI: 10.36660/ijcs.20200415 Visualizações 1
IJCS
Editorial

Abdominal Subcutaneous Adipose Tissue, Diet, and Risk of Cardiovascular Disease: What do we Know?

Camila Weschenfelder et al. Penny M. Kris-Etherton

Excess adiposity increases the risk of cardiovascular disease (CVD) due to dyslipidemia, systemic inflammation and other risk factors. The distribution of body fat depots, and central adiposity in particular, is related to cardiometabolic diseases. The different adipose tissue depots in the body, ie, epicardial adipose tissue, visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT), have different biochemical characteristics and produce unique biologically active molecules that affect normal and pathological processes related to CVD risk. , Abdominal SAT is classified as superficial or deep. Deep subcutaneous adipose tissue (DSAT) has a higher ratio of saturated to monounsaturated fatty acids, and, consequently, is more saturated than superficial subcutaneous adipose tissue (SSAT). Despite being in the subcutaneous compartment, DSAT differs from VAT because of differences in gene transcription, having different metabolic functions than SSAT.

In Acute Coronary Syndrome (ACS) patients, coronary plaque instability is related to abnormal abdominal fat distribution. Analyses of the abdominal fat distribution of ACS patients have demonstrated that both VAT and SAT are positively correlated with vessel and plaque volumes, but not with plaque tissue components, the fibrous and lipid content of plaque. However, considering coronary plaque characteristics, a higher VAT/SAT ratio was independently associated with a higher percentage of plaque lipid content, with a lower percentage of fibrous volumes and a thinner fibrous cap thickness, characteristics that define greater plaque rupture vulnerability and a high risk for coronary events.

[…]

  • Abdominal Subcutaneous Fat
  • acute coronary syndrome
  • Diet
  • Inflammation
  • Metabolic Syndrome
  • Obesity, Abdominal
  • Risk Factors/prevention and control
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Creative Commons Attribution (CC BY) Creative Commons license
14/01/2022 DOI: 10.36660/ijcs.20210233 Visualizações 2

Como citar este artigo

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Cavalcanti IML, Nascimento CR, Tenório PP, Araújo TFS. Analysis of the Influence of Abdominal Obesity on Systemic Arterial Hypertension and on the Lipid Profile on Cardiometabolic Risk Stratification in Adult Women. International Journal of Cardiovascular Sciences 2022;35(5):625-34.

Formato de Documento Eletrônico (ABNT)

Cavalcanti, Iury Matheus Lima; Nascimento, Cristian Rodrigues do; Tenório, Pedro Pereira; Araújo, Tiago Ferreira da Silva. Analysis of the Influence of Abdominal Obesity on Systemic Arterial Hypertension and on the Lipid Profile on Cardiometabolic Risk Stratification in Adult Women. International Journal of Cardiovascular Sciences, v. 35, n. 5, p. 625-634, mar. 2022.

Formato de Documento Eletrônico (APA)

Cavalcanti, I. M. L., Nascimento, C. R. , Tenório, P. P., & Araújo, T. F. S. (2022). Analysis of the Influence of Abdominal Obesity on Systemic Arterial Hypertension and on the Lipid Profile on Cardiometabolic Risk Stratification in Adult Women. International Journal of Cardiovascular Sciences, 35(5), 625-634.

Formato de Documento Eletrônico (ISO)

Cavalcanti, Iury Matheus Lima and Nascimento, Cristian Rodrigues do and Tenório, Pedro Pereira and Araújo, Tiago Ferreira da Silva. Analysis of the Influence of Abdominal Obesity on Systemic Arterial Hypertension and on the Lipid Profile on Cardiometabolic Risk Stratification in Adult Women. International Journal of Cardiovascular Sciences [online]. 2022, vol. 35, n. 5, [citado 2026-10-14], pp. 625-634. Disponível em: <https://journals.cardiol.br/article/analysis-of-the-influence-of-abdominal-obesity-on-systemic-arterial-hypertension-and-on-the-lipid-profile-on-cardiometabolic-risk-stratification-in-adult-women-2/>. ISSN 2359-4802

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Weschenfelder C, Kris-Etherton PM. Abdominal Subcutaneous Adipose Tissue, Diet, and Risk of Cardiovascular Disease: What do we Know?. International Journal of Cardiovascular Sciences 2022;35(1):46-7.

Formato de Documento Eletrônico (ABNT)

Weschenfelder, Camila; Kris-Etherton, Penny M.. Abdominal Subcutaneous Adipose Tissue, Diet, and Risk of Cardiovascular Disease: What do we Know?. International Journal of Cardiovascular Sciences, v. 35, n. 1, p. 46-47, jan. 2022.

Formato de Documento Eletrônico (APA)

Weschenfelder, C., & Kris-Etherton, P. M. (2022). Abdominal Subcutaneous Adipose Tissue, Diet, and Risk of Cardiovascular Disease: What do we Know?. International Journal of Cardiovascular Sciences, 35(1), 46-47.

Formato de Documento Eletrônico (ISO)

Weschenfelder, Camila and Kris-Etherton, Penny M.. Abdominal Subcutaneous Adipose Tissue, Diet, and Risk of Cardiovascular Disease: What do we Know?. International Journal of Cardiovascular Sciences [online]. 2022, vol. 35, n. 1, [citado 2026-10-14], pp. 46-47. Disponível em: <https://journals.cardiol.br/article/abdominal-subcutaneous-adipose-tissue-diet-and-risk-of-cardiovascular-disease-what-do-we-know-2/>. ISSN 2359-4802

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