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  2. Palavra-chave: hypercholesterolemia
ABC
Original Article

Prevalence of dyslipidemia and risk factors in Campos dos Goytacazes, in the Brazilian State of Rio de Janeiro

Luiz José de Souza et al. João Tadeu Damian Souto Filho Thiago Ferreira de Souza Aldo Franklin Ferreira Reis … Carlos Gicovate Neto Diogo Assed Bastos Vitor Azevedo Côrtes Félix Elias Barros Chalita Cláudio Luiz Teixeira

OBJECTIVE: To determine the prevalence of dyslipidemias in adults in the city of Campos dos Goytacazes, in the Brazilian state of Rio de Janeiro, and to identify its relation to risk factors. METHODS: Cross-sectional, population-based, observational study with sampling through conglomerates and stratified according to socioeconomic levels, sex, and age, with 1,039 individuals. Risk factors, familial history, blood pressure, anthropometric measurements, glucose, triglycerides and cholesterol were determined. RESULTS: The following prevalences were observed: of dyslipidemias 24.2%; of hypercholesterolemia, 4.2%; of elevated LDL-C, 3.5%; of low HDL-C, 18.3%; and of hypertriglyceridemia, 17.1%. The following mean levels were observed: cholesterol, 187.6± 33.7 mg/dL; LDL-C, 108.7±26.8 mg/dL; HDL-C, 48.5±7.7 mg/dL; and triglycerides, 150.1±109.8 mg/dL. The following variables showed a positive correlation with dyslipidemia: increased age (P<0.001), male sex (P<0.001), low familial income (P<0.001), familial history (P<0.01), overweight/obesity (P<0.001), waist measure (P<0.001), high blood pressure (P<0.001), and diabetes mellitus (P<0.001). The following variables had no influence on dyslipidemias: ethnicity, educational level, smoking habits, and sedentary lifestyle. CONCLUSION: The frequency of lipid changes in the population studied was high, suggesting that measures for the early diagnosis should be taken, in association with implementation of programs for primary and secondary prevention of atherosclerosis.

  • Dyslipidemias
  • hypercholesterolemia
  • hyperlipidemia
  • Hypertriglyceridemia
  • prevalence
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Creative Commons Attribution (CC BY) Creative Commons license
09/10/2003 DOI: 10.1590/S0066-782X2003001100005 Visualizações 2
ABC
Original Article

Coronary heart disease clinical manifestation and risk factors in Japanese immigrants and their descendents in the city of São Paulo

Reynaldo Vicente Amato et al. Luiz Antonio Machado César Antonio de Pádua Mansur Whady Armindo Hueb … José Renato Martines Martins Caio de Brito Vianna José Antonio Franchini Ramires

OBJECTIVE: To assess whether a difference exists in coronary heart disease clinical manifestations and the prevalence of risk factors between Japanese immigrants and their descendents in the city of São Paulo. METHODS: Retrospective analysis of coronary artery disease clinical manifestations and the prevalence of risk factors, comparing 128 Japanese immigrants (Japanese group) with 304 Japanese descendents (Nisei group). RESULTS: The initial manifestation of the disease was earlier in the Nisei group (mean = 53 years), a difference of 12 years when compared with that in the Japanese group (mean = 65 years) (P<0.001). Myocardial infarction was the first manifestation in both groups (P = 0.83). The following parameters were independently associated with early coronary events: smoking (OR = 2.25; 95% CI = 1.35-3.77; P<0.002); Nisei group (OR = 10.22; 95% CI = 5.64-18.5; P<0.001); and female sex (OR = 5.04; 95% CI = 2.66-9.52; P<0.001). CONCLUSION: The clinical presentation of coronary heart disease in the Japanese and their descendents in the city of São Paulo was similar, but coronary heart disease onset occurred approximately 12 years earlier in the Nisei group than in the Japanese group.

  • coronary heart disease
  • Diabetes mellitus
  • hypercholesterolemia
  • Hypertriglyceridemia
  • systemic arterial hypertension
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Creative Commons Attribution (CC BY) Creative Commons license
09/10/2003 DOI: 10.1590/S0066-782X2003001100003
ABC
Original Article

Impact of nutritional counseling in reducing serum cholesterol in public health service patients

Maria da Conceição Rosado Batista et al. Sylvia do Carmo Castro Franceschini

OBJECTIVE: To assess the impact of nutritional attention on the lipid profile and nutritional status of hypercholesterolemic patients attended in health centers of Belo Horizonte. METHODS: Using nutritional attendance patient record cards from two health units, the evolution of the lipid profile and the nutritional state (BMI) was monitored of 96 hypercholesterolemic patients who received diet. The patients were appraised at the following moments: initial (1st consultation), after 3 months (2nd consultation) and last consultation (variable for each patient). RESULTS: On the first attendance, 44,4% of the patients presented not only high total cholesterol and LDL-c, but also hypertriglyceridemia and 70.3% were overweight or obese, but most patients (75.6%) presented adequate HDL-c levels. There was significant reduction in the BMI, total cholesterol, LDL-c values (p < 0.01) and also in the triglyceride levels (p < 0.05) in the first three months, without alteration in the HDL-c levels. A significant reduction (p < 0.01) was observed in the frequency of individuals with high cholesterol (from 89.6% down to 47.9%), high and very high LDL-c (from 82.6% down to 45.7%), as well as high and very high triglyceride (from 43.6% down to 16.7%). The observed reduction in frequency of the low HDL-c was statistically meaningless. CONCLUSION: This study evidences the effect of the nutritional attention on lipid profile in hypercholesterolemic patients, reinforcing the need for a multiprofessional team to attend them at the public health services.

  • Diet
  • hypercholesterolemia
  • nutritional status
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Creative Commons Attribution (CC BY) Creative Commons license
02/04/2003 DOI: 10.1590/S0066-782X2003000200005 Visualizações 1
ABC
Original Article

Comparison of the effect of two HMG CoA reductase inhibitors on LDL susceptibility to oxidation

Vera Lúcia Portal et al. Emílio H. Moriguchi José Luiz da Costa Vieira Sadi Schio … Eduardo T. Mastalir Fabiana Buffé Eleni Borges Bortolini Ricardo Santalucia Brüch Rubem Rodrigues

OBJECTIVE: To study the differences between fluvastatin and pravastatin regarding LDL susceptibility to oxidation, plasma levels of total cholesterol (TC), HDL-C, LDL-C and triglycerides (TG) in hypercholesterolemic patients with established coronary heart disease (CHD). METHODS: A double-blind randomized parallel study was conducted that included 41 hypercholesterolemic outpatients with CHD treated at the Instituto de Cardiologia do Rio Grande do Sul. The inclusion criteria were LDL-C above 100 mg/dL and triglycerides below 400 mg/dL based on 2 measures. After 4 weeks on a low cholesterol diet, those patients that fullfilled the inclusion criteria were randomized into 2 groups: the fluvastatin group (fluvastatin 40 mg/day) and the pravastatin group (pravastatin 20 mg/day), for 24 weeks of treatment. LDL susceptibility to oxidation was analyzed with copper-induced production of conjugated dienes (Cu2+) and water-soluble free radical initiator azo-bis (2′-2’amidinopropanil) HCl (AAPH). Spectroscopy nuclear magnetic resonance was used for determination of lipids. RESULTS: After 24 weeks of drug therapy, fluvastatin and pravastatin significantly reduced LDL susceptibility to oxidation as demonstrated by the reduced rate of oxidation (azo and Cu) and by prolonged azo-induced lag time (azo lag). The TC, LDL-C, and TG reduced significantly and HDL-C increased significantly. No differences between the drugs were observed. CONCLUSION: In hypercholesterolemic patients with CHD, both fluvastatin and pravastatin reduced LDL susceptibility to oxidation.

  • hypercholesterolemia
  • LDL oxidation
  • statins
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02/04/2003 DOI: 10.1590/S0066-782X2003000200004
ABC
Original Article

Prescription and adherence to statins of patients with coronary artery disease and hypercholesterolemia

Antonio P. Mansur et al. André P. L. Mattar Cristiane E. Tsubo Danielle T. Simão … Fábio R. Yoshi Kuang Daci

OBJECTIVE: Statins have proved to be safe and effective in the secondary prevention of coronary artery disease, but the level of prescription and the reasons for nonadherence to treatment in many coronariopathy treatment centers has not been determined. The purpose of this study was to identify reasons for nonadherence to statin therapy. METHODS: We analyzed 207 consecutive patients with coronary artery disease and hypercholesterolemia (total cholesterol > or = 200mg/dL or LDL – cholesterol > or = 130mg/dL). Patients’ average age was 61.7±10 year; 111 (53.6%) male were and 94 (46.6%) were female. We analyzed the level of prescription and adherence to treatment with statins. RESULTS: Statins were prescribed for 139 (67%) patients, but only 85 (41%) used the drug. In spite of being indicated, statins were not prescribed in 68 (33%) patients. Of 54 (26%) patients, nonadherent to statins, 67% did not use the drug due to its high cost, 31% due to the lack of instruction, and only 2% due to side effects. Total cholesterol (260.3±42.2 vs 226.4±51.9; p<0.0001) and LDL cholesterol (174.6±38.1 vs 149.6±36.1; p<0.0001) were lower in patients on medication. HDL-cholesterol increased from 37.6±9.6 to 41.5±12.9mg/dL (p=0.02), and triglycerides were not modified in patients using statins. CONCLUSION: The prescription of statins in patients with coronary artery disease and dyslipidemia is high; however, its adherence is far from satisfactory, due to the high cost of the medication. Reduction in total cholesterol and LDL cholesterol levels did not reach the targets recommended by the Brazilian Consensus on Dyslipidemia.

  • adherence
  • Coronary Artery Disease
  • hypercholesterolemia
  • statins
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08/01/2002 DOI: 10.1590/S0066-782X2001000200002 Visualizações 1

Como citar este artigo

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Souza LJ, Souto Filho JTD, Souza TF, Reis AFF, Gicovate Neto C, Bastos DA, Côrtes VA, et al. Prevalence of dyslipidemia and risk factors in Campos dos Goytacazes, in the Brazilian State of Rio de Janeiro. Arquivos Brasileiros de Cardiologia 2003;81(3):257-64.

Formato de Documento Eletrônico (ABNT)

Souza, Luiz José de; Souto Filho, João Tadeu Damian; Souza, Thiago Ferreira de; Reis, Aldo Franklin Ferreira; Gicovate Neto, Carlos; Bastos, Diogo Assed; Côrtes, Vitor Azevedo; Chalita, Félix Elias Barros; Teixeira, Cláudio Luiz. Prevalence of dyslipidemia and risk factors in Campos dos Goytacazes, in the Brazilian State of Rio de Janeiro. Arquivos Brasileiros de Cardiologia, v. 81, n. 3, p. 257-264, out. 2003.

Formato de Documento Eletrônico (APA)

Souza, L. J. , Souto Filho, J. T. D., Souza, T. F. , Reis, A. F. F., Gicovate Neto, C., Bastos, D. A., Côrtes, V. A., Chalita, F. E. B., & Teixeira, C. L. (2003). Prevalence of dyslipidemia and risk factors in Campos dos Goytacazes, in the Brazilian State of Rio de Janeiro. Arquivos Brasileiros de Cardiologia, 81(3), 257-264.

Formato de Documento Eletrônico (ISO)

Souza, Luiz José de and Souto Filho, João Tadeu Damian and Souza, Thiago Ferreira de and Reis, Aldo Franklin Ferreira and Gicovate Neto, Carlos and Bastos, Diogo Assed and Côrtes, Vitor Azevedo and Chalita, Félix Elias Barros and Teixeira, Cláudio Luiz. Prevalence of dyslipidemia and risk factors in Campos dos Goytacazes, in the Brazilian State of Rio de Janeiro. Arquivos Brasileiros de Cardiologia [online]. 2003, vol. 81, n. 3, [citado 2026-10-14], pp. 257-264. Disponível em: <https://journals.cardiol.br/article/prevalence-of-dyslipidemia-and-risk-factors-in-campos-dos-goytacazes-in-the-brazilian-state-of-rio-de-janeiro-2/>. ISSN 0066-782X

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Amato RV, César LAM, Mansur AP, Hueb WA, Martins JRM, Vianna CB, Ramires JAF, et al. Coronary heart disease clinical manifestation and risk factors in Japanese immigrants and their descendents in the city of São Paulo. Arquivos Brasileiros de Cardiologia 2003;81(3):234-8.

Formato de Documento Eletrônico (ABNT)

Amato, Reynaldo Vicente; César, Luiz Antonio Machado; Mansur, Antonio de Pádua; Hueb, Whady Armindo; Martins, José Renato Martines; Vianna, Caio de Brito; Ramires, José Antonio Franchini. Coronary heart disease clinical manifestation and risk factors in Japanese immigrants and their descendents in the city of São Paulo. Arquivos Brasileiros de Cardiologia, v. 81, n. 3, p. 234-238, out. 2003.

Formato de Documento Eletrônico (APA)

Amato, R. V., César, L. A. M., Mansur, A. P., Hueb, W. A., Martins, J. R. M., Vianna, C. B., & Ramires, J. A. F. (2003). Coronary heart disease clinical manifestation and risk factors in Japanese immigrants and their descendents in the city of São Paulo. Arquivos Brasileiros de Cardiologia, 81(3), 234-238.

Formato de Documento Eletrônico (ISO)

Amato, Reynaldo Vicente and César, Luiz Antonio Machado and Mansur, Antonio de Pádua and Hueb, Whady Armindo and Martins, José Renato Martines and Vianna, Caio de Brito and Ramires, José Antonio Franchini. Coronary heart disease clinical manifestation and risk factors in Japanese immigrants and their descendents in the city of São Paulo. Arquivos Brasileiros de Cardiologia [online]. 2003, vol. 81, n. 3, [citado 2026-10-14], pp. 234-238. Disponível em: <https://journals.cardiol.br/article/coronary-heart-disease-clinical-manifestation-and-risk-factors-in-japanese-immigrants-and-their-descendents-in-the-city-of-sao-paulo-2/>. ISSN 0066-782X

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Batista MCR, Franceschini SCC. Impact of nutritional counseling in reducing serum cholesterol in public health service patients. Arquivos Brasileiros de Cardiologia 2003;80(2):167-70.

Formato de Documento Eletrônico (ABNT)

Batista, Maria da Conceição Rosado; Franceschini, Sylvia do Carmo Castro. Impact of nutritional counseling in reducing serum cholesterol in public health service patients. Arquivos Brasileiros de Cardiologia, v. 80, n. 2, p. 167-170, abr. 2003.

Formato de Documento Eletrônico (APA)

Batista, M. C. R., & Franceschini, S. C. C. (2003). Impact of nutritional counseling in reducing serum cholesterol in public health service patients. Arquivos Brasileiros de Cardiologia, 80(2), 167-170.

Formato de Documento Eletrônico (ISO)

Batista, Maria da Conceição Rosado and Franceschini, Sylvia do Carmo Castro. Impact of nutritional counseling in reducing serum cholesterol in public health service patients. Arquivos Brasileiros de Cardiologia [online]. 2003, vol. 80, n. 2, [citado 2026-10-14], pp. 167-170. Disponível em: <https://journals.cardiol.br/article/impact-of-nutritional-counseling-in-reducing-serum-cholesterol-in-public-health-service-patients-2/>. ISSN 0066-782X

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Portal VL, Moriguchi EH, Vieira JLC, Schio S, Mastalir ET, Buffé F, Bortolini EB, et al. Comparison of the effect of two HMG CoA reductase inhibitors on LDL susceptibility to oxidation. Arquivos Brasileiros de Cardiologia 2003;80(2):156-61.

Formato de Documento Eletrônico (ABNT)

Portal, Vera Lúcia; Moriguchi, Emílio H.; Vieira, José Luiz da Costa; Schio, Sadi; Mastalir, Eduardo T.; Buffé, Fabiana; Bortolini, Eleni Borges; Brüch, Ricardo Santalucia; Rodrigues, Rubem. Comparison of the effect of two HMG CoA reductase inhibitors on LDL susceptibility to oxidation. Arquivos Brasileiros de Cardiologia, v. 80, n. 2, p. 156-161, abr. 2003.

Formato de Documento Eletrônico (APA)

Portal, V. L., Moriguchi, E. H., Vieira, J. L. C., Schio, S., Mastalir, E. T., Buffé, F., Bortolini, E. B., Brüch, R. S., & Rodrigues, R. (2003). Comparison of the effect of two HMG CoA reductase inhibitors on LDL susceptibility to oxidation. Arquivos Brasileiros de Cardiologia, 80(2), 156-161.

Formato de Documento Eletrônico (ISO)

Portal, Vera Lúcia and Moriguchi, Emílio H. and Vieira, José Luiz da Costa and Schio, Sadi and Mastalir, Eduardo T. and Buffé, Fabiana and Bortolini, Eleni Borges and Brüch, Ricardo Santalucia and Rodrigues, Rubem. Comparison of the effect of two HMG CoA reductase inhibitors on LDL susceptibility to oxidation. Arquivos Brasileiros de Cardiologia [online]. 2003, vol. 80, n. 2, [citado 2026-10-14], pp. 156-161. Disponível em: <https://journals.cardiol.br/article/comparison-of-the-effect-of-two-hmg-coa-reductase-inhibitors-on-ldl-susceptibility-to-oxidation-2/>. ISSN 0066-782X

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Mansur AP, Mattar APL, Tsubo CE, Simão DT, Yoshi FR, Daci K. Prescription and adherence to statins of patients with coronary artery disease and hypercholesterolemia. Arquivos Brasileiros de Cardiologia 2002;76(2):115-8.

Formato de Documento Eletrônico (ABNT)

Mansur, Antonio P.; Mattar, André P. L.; Tsubo, Cristiane E.; Simão, Danielle T.; Yoshi, Fábio R.; Daci, Kuang. Prescription and adherence to statins of patients with coronary artery disease and hypercholesterolemia. Arquivos Brasileiros de Cardiologia, v. 76, n. 2, p. 115-118, jan. 2002.

Formato de Documento Eletrônico (APA)

Mansur, A. P., Mattar, A. P. L., Tsubo, C. E., Simão, D. T., Yoshi, F. R., & Daci, K. (2002). Prescription and adherence to statins of patients with coronary artery disease and hypercholesterolemia. Arquivos Brasileiros de Cardiologia, 76(2), 115-118.

Formato de Documento Eletrônico (ISO)

Mansur, Antonio P. and Mattar, André P. L. and Tsubo, Cristiane E. and Simão, Danielle T. and Yoshi, Fábio R. and Daci, Kuang. Prescription and adherence to statins of patients with coronary artery disease and hypercholesterolemia. Arquivos Brasileiros de Cardiologia [online]. 2002, vol. 76, n. 2, [citado 2026-10-14], pp. 115-118. Disponível em: <https://journals.cardiol.br/article/prescription-and-adherence-to-statins-of-patients-with-coronary-artery-disease-and-hypercholesterolemia-2/>. ISSN 0066-782X

  • Sobre a Família ABC
  • Regimento Interno
  • Conselho Editorial
  • Sociedade Brasileira de Cardiologia (SBC)

Edições

Diretrizes da SBC

  • Vídeos
  • Podcasts
  • Notícias