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  2. Palavra-chave: digital health
IJCS
Review Article

How Artificial Intelligence Can Transform Women's Healthcare Across All Life Stages

Larissa Neto Espíndola et al. Elise Sant’Ana Isaías Gláucia Maria Moraes de Oliveira Alexandra Monteiro

Abstract

Artificial intelligence (AI) has been driving significant transformations in healthcare by enhancing diagnostics, personalizing treatments, and optimizing clinical workflows. In women’s health, it offers innovative approaches for prevention, early detection, and management of various conditions throughout life — from adolescence to old age.

Over the past decade, advances in machine learning algorithms, neural networks, and natural language processing have enabled the analysis of large volumes of clinical data with previously unimaginable precision and speed. However, the integration of AI into women’s healthcare remains underutilized, representing a valuable opportunity to reduce social inequalities that influence adverse health outcomes.

However, the use of AI in women’s healthcare raises important ethical concerns, particularly the need to protect patients’ sensitive data, avoid algorithmic biases that may perpetuate stigma or inequality, and ensure safe, equitable, and responsible implementation. Ethical governance — with national and international guidelines and regulations — is essential to ensure that AI benefits all women, including vulnerable and underrepresented populations, without exacerbating existing disparities.

This manuscript aims to synthesize the main applications of AI in women’s health across different life stages, identifying advances, opportunities, and challenges in this context. Given the complexity and multidisciplinary nature of the topic, we conducted a scoping review – an appropriate methodology for exploring emerging and still underdeveloped fields. In addition to scientific databases, we included a complementary search in digital health app libraries to identify technological solutions already implemented or under development for women’s health.

  • Artificial Intelligence
  • Cardiovascular disease
  • digital health
  • eHealth
  • women's healthcare
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Creative Commons Attribution (CC BY) Creative Commons license
27/04/2026 DOI: 10.36660/ijcs.20250033 Visualizações 2
IJCS
Original Article

Impact of Digital Technology Intervention on Medication Compliance, Modification of Risk Factors, and Clinical Outcome in Patients With Acute Coronary Syndrome: A Follow-Up Study

C. J Devaraju et al. S Sunil Kumar K. S. Sadananda K Vinay Kumar … Veena Nanjappa K. S. Rajith K. S. Ravindranath

Abstract

Background

Coronary artery disease (CAD) is prevalent worldwide, presenting significant morbidity and mortality. Despite the advances in the management of CAD, the primary focus continues to be risk factor reduction, lifestyle changes, and medication adherence, all of which contribute considerably to favorable outcomes. Long-term CAD outcomes tend to be poor, especially in developing countries, due to medication non-compliance, a lack of education, and appropriate measures for the modification of risk factors.

Objectives

The present study aims to investigate the use of digital technology in assessing medication compliance, modifying risk factors, and evaluating clinical outcomes in patients with acute coronary syndrome (ACS).

Methods

A prospective, randomized study will be conducted with patients diagnosed with ACS at the Sri Jayadeva Institute of Cardiovascular Disease and Research, Mysore, and JSS Medical College, Mysore, India. A total of 522 patients will be randomized in a 1:1 ratio into either the digital intervention group or the control group. Digital technology registration will be completed during hospitalization, with guidance from the research team. Follow-up assessments will occur every three months for one year. Statistical analysis will be conducted at a 5% significance level. Categorical variables will be analyzed using the Z test for proportions or the Chi-square test, while continuous variables will be assessed using the independent sample t-test.

Results

The results will be presented after data collection and statistical analysis. This study aims to focus on clinical outcomes in patients with ACS, highlighting the importance of lifestyle modification, adherence to medications, and modifications of risk factors by digital technology, bridging the gap between patients and healthcare providers.

Conclusions

We intend for the outcomes of this study to produce an initiative for larger randomized control trials regarding web application in the management of ACS. Favorable outcomes could significantly impact the management of ACS, and web applications can be recommended as part of a routine standard of care established by societal guidelines.

  • acute coronary syndrome
  • digital health
  • digital technology
  • Risk Factors
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Creative Commons Attribution (CC BY) Creative Commons license
03/03/2025 DOI: 10.36660/ijcs.20240127 Visualizações 1
IJCS
Original Article

Virtual Reality and Physical Activity in Patients with Heart Failure: Technology Validation and User Satisfaction – Pilot Study

Ariele dos Santos Costa et al. Caroline Bublitz Barbosa Solange Guizilini Vagner Rogério dos Santos … Carla Roberta Miura Múcio Tavares de Oliveira Junior Anabela Gonçalves da Silva Rita Simone Lopes Moreira

Abstract

Background

Digital health uses innovative information technology for healthcare needs. Virtual reality (VR) is increasingly adopted in healthcare, including cardiovascular rehabilitation (CVR), to improve performance and adherence. However, digital interventions must consider users’ perspectives to prevent VR from becoming a barrier.

Objective

This study aimed to assess the usability and enjoyment of physical activity associated with VR among inpatients with heart failure (HF).

Method

A prospective pilot study was conducted with ten patients diagnosed with HF. Participants completed an exercise program on a cycle ergometer with immersive VR for lower limb training. Anxiety and depression symptoms, physical activity enjoyment, and system usability were evaluated. Statistical analysis included descriptive and inferential analyses with a 5% significance level (p<0.05). Pearson's test was used for correlation analysis.

Results

The population’s tendency to experience anxiety and depression was evaluated, and the sample favorably assessed the system’s usability, with a mean score of 68.2 (standard deviation ±17.8); exercise enjoyment scored 79.6 (±7.7). No significant correlations were found between anxiety and depression profiles and usability or exercise enjoyment, suggesting further study phases.

Conclusions

VR can complement rehabilitation programs for HF patients, potentially improving performance and adherence. Additional research is required to evaluate the effectiveness of VR-associated physical activity on clinical outcomes in HF patients.

  • digital health
  • Heart Failure
  • Rehabilitation
  • Virtual reality
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Creative Commons Attribution (CC BY) Creative Commons license
28/02/2025 DOI: 10.36660/ijcs.20240067 Visualizações 2

Como citar este artigo

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Espíndola LN, Isaías ES, Oliveira GMM, Monteiro A. How Artificial Intelligence Can Transform Women’s Healthcare Across All Life Stages. International Journal of Cardiovascular Sciences 2026;39:e20250033.

Formato de Documento Eletrônico (ABNT)

Espíndola, Larissa Neto; Isaías, Elise Sant’Ana; Oliveira, Gláucia Maria Moraes de; Monteiro, Alexandra. How Artificial Intelligence Can Transform Women’s Healthcare Across All Life Stages. International Journal of Cardiovascular Sciences, v. 39, e20250033, abr. 2026.

Formato de Documento Eletrônico (APA)

Espíndola, L. N., Isaías, E. S., Oliveira, G. M. M. , & Monteiro, A. (2026). How Artificial Intelligence Can Transform Women’s Healthcare Across All Life Stages. International Journal of Cardiovascular Sciences, 39, e20250033.

Formato de Documento Eletrônico (ISO)

Espíndola, Larissa Neto and Isaías, Elise Sant’Ana and Oliveira, Gláucia Maria Moraes de and Monteiro, Alexandra. How Artificial Intelligence Can Transform Women’s Healthcare Across All Life Stages. International Journal of Cardiovascular Sciences [online]. 2026, vol. 39, [citado 2026-10-14], e20250033. Disponível em: <https://journals.cardiol.br/article/how-artificial-intelligence-can-transform-womens-healthcare-across-all-life-stages-2/>. ISSN 2359-4802

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Devaraju CJ, Kumar SS, Sadananda KS, Kumar KV, Nanjappa V, Rajith KS, Ravindranath KS, et al. Impact of Digital Technology Intervention on Medication Compliance, Modification of Risk Factors, and Clinical Outcome in Patients With Acute Coronary Syndrome: A Follow-Up Study. International Journal of Cardiovascular Sciences 2025;38:e20240127.

Formato de Documento Eletrônico (ABNT)

Devaraju, C. J; Kumar, S Sunil; Sadananda, K. S.; Kumar, K Vinay; Nanjappa, Veena; Rajith, K. S.; Ravindranath, K. S.. Impact of Digital Technology Intervention on Medication Compliance, Modification of Risk Factors, and Clinical Outcome in Patients With Acute Coronary Syndrome: A Follow-Up Study. International Journal of Cardiovascular Sciences, v. 38, e20240127, mar. 2025.

Formato de Documento Eletrônico (APA)

Devaraju, C. J., Kumar, S. S., Sadananda, K. S., Kumar, K. V., Nanjappa, V., Rajith, K. S., & Ravindranath, K. S. (2025). Impact of Digital Technology Intervention on Medication Compliance, Modification of Risk Factors, and Clinical Outcome in Patients With Acute Coronary Syndrome: A Follow-Up Study. International Journal of Cardiovascular Sciences, 38, e20240127.

Formato de Documento Eletrônico (ISO)

Devaraju, C. J and Kumar, S Sunil and Sadananda, K. S. and Kumar, K Vinay and Nanjappa, Veena and Rajith, K. S. and Ravindranath, K. S.. Impact of Digital Technology Intervention on Medication Compliance, Modification of Risk Factors, and Clinical Outcome in Patients With Acute Coronary Syndrome: A Follow-Up Study. International Journal of Cardiovascular Sciences [online]. 2025, vol. 38, [citado 2026-10-14], e20240127. Disponível em: <https://journals.cardiol.br/article/impact-of-digital-technology-intervention-on-medication-compliance-modification-of-risk-factors-and-clinical-outcome-in-patients-with-acute-coronary-syndrome-a-follow-up-study-2/>. ISSN 2359-4802

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Costa AS, Barbosa CB, Guizilini S, Santos VR, Miura CR, Oliveira Junior MT, Silva AG, et al. Virtual Reality and Physical Activity in Patients with Heart Failure: Technology Validation and User Satisfaction – Pilot Study. International Journal of Cardiovascular Sciences 2025;38:e20240067.

Formato de Documento Eletrônico (ABNT)

Costa, Ariele dos Santos; Barbosa, Caroline Bublitz; Guizilini, Solange; Santos, Vagner Rogério dos; Miura, Carla Roberta; Oliveira Junior, Múcio Tavares de; Silva, Anabela Gonçalves da; Moreira, Rita Simone Lopes. Virtual Reality and Physical Activity in Patients with Heart Failure: Technology Validation and User Satisfaction – Pilot Study. International Journal of Cardiovascular Sciences, v. 38, e20240067, fev. 2025.

Formato de Documento Eletrônico (APA)

Costa, A. S., Barbosa, C. B., Guizilini, S., Santos, V. R. , Miura, C. R., Oliveira Junior, M. T. , Silva, A. G. , & Moreira, R. S. L. (2025). Virtual Reality and Physical Activity in Patients with Heart Failure: Technology Validation and User Satisfaction – Pilot Study. International Journal of Cardiovascular Sciences, 38, e20240067.

Formato de Documento Eletrônico (ISO)

Costa, Ariele dos Santos and Barbosa, Caroline Bublitz and Guizilini, Solange and Santos, Vagner Rogério dos and Miura, Carla Roberta and Oliveira Junior, Múcio Tavares de and Silva, Anabela Gonçalves da and Moreira, Rita Simone Lopes. Virtual Reality and Physical Activity in Patients with Heart Failure: Technology Validation and User Satisfaction – Pilot Study. International Journal of Cardiovascular Sciences [online]. 2025, vol. 38, [citado 2026-10-14], e20240067. Disponível em: <https://journals.cardiol.br/article/virtual-reality-and-physical-activity-in-patients-with-heart-failure-technology-validation-and-user-satisfaction-pilot-study-2/>. ISSN 2359-4802

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