Review Article

Atrial Functional Mitral Regurgitation

Abstract

Secondary mitral insufficiency (MI) in the setting of ventricular disease has always been a topic at conferences and has achieved extensive pathophysiological knowledge over the years. More recently, with the increasing incidence of atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF), a new phenotype that had been little discussed has come to light: atrial functional mitral regurgitation. In this entity, special attention should be addressed to the left atrium and the mitral annulus because, in early stages, they present normal left ventricular dimensions and function.

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