Limitations in the Diagnosis of Noncompaction Cardiomyopathy by Echocardiography
Critical analysis
The diagnostic criteria described by Jenni et al. and Chin et al. are based on the measurement of NCM and CM thicknesses. However, the criteria differ regarding the cardiac cycle point at which the measurements should be taken. Chin et al. propose the measurements of NCM and CM thickness be performed at end-diastole, while Jenni et al. propose them at end-systole.
The criteria proposed by Jenni et al. used an NCM/CM ratio > 2 at end-systole, generating higher specificity and lower sensitivity as compared to the criteria by Chin et al., who use the CM/(NCM + CM) ratio ≤ 0.5. However, the increase in sensitivity is due to a decrease in specificity, as compared to the criteria by Jenni et al.
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