Cardiac Magnetic Resonance and Amyloidosis: How can it Assist Clinical Reasoning?

Evaluation of cardiac morphology

CA leads to changes in cardiac structure. In the atria, dilatation and increased thickness of the septum usually occur, while, in more advanced phases, there may be slow flow and thrombi, which, when arrhythmias are present, may be difficult to identify via CMR.

The ventricular myocardium usually shows increased thickness, typically at levels higher than those observed in patients with arterial hypertension; the levels are typically greater in forms of transthyretin amyloidosis than in light chain amyloidosis, and they may involve both ventricles. ^,

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