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  2. Keyword: Receptors, Interleukin
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Review Article

Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure

Humberto Villacorta et al. Alan S. Maisel

Abstract

ST2 is a member of the interleukin-1 receptor family biomarker and circulating soluble ST2 concentrations are believed to reflect cardiovascular stress and fibrosis. Recent studies have demonstrated soluble ST2 to be a strong predictor of cardiovascular outcomes in both chronic and acute heart failure. It is a new biomarker that meets all required criteria for a useful biomarker. Of note, it adds information to natriuretic peptides (NPs) and some studies have shown it is even superior in terms of risk stratification. Since the introduction of NPs, this has been the most promising biomarker in the field of heart failure and might be particularly useful as therapy guide.

  • Biomarkers, Pharmacological
  • Heart Failure /therapy
  • Prognosis
  • Receptors, Interleukin
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Creative Commons Attribution (CC BY) Creative Commons license
15/01/2016 DOI: 10.5935/abc.20150151

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Villacorta H, Maisel AS. Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure. Arquivos Brasileiros de Cardiologia 2016;106(2):145-52.

Electronic Document Format (ABNT)

Villacorta, Humberto; Maisel, Alan S.. Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure. Arquivos Brasileiros de Cardiologia, v. 106, n. 2, p. 145-152, Jan. 2016.

Electronic Document Format (APA)

Villacorta, H., & Maisel, A. S. (2016). Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure. Arquivos Brasileiros de Cardiologia, 106(2), 145-152.

Electronic Document Format (ISO)

Villacorta, Humberto and Maisel, Alan S.. Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure. Arquivos Brasileiros de Cardiologia [online]. 2016, vol. 106, n. 2, [cited 2026-10-14], pp. 145-152. Available from: <https://journals.cardiol.br/en/article/soluble-st2-testing-a-promising-biomarker-in-the-management-of-heart-failure/>. ISSN 0066-782X

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