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  2. Keyword: Drug Prescriptions
Evidence-based therapy prescription in high-cardiovascular risk patients: the REACT study
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Special Article

Evidence-based therapy prescription in high-cardiovascular risk patients: the REACT study

Otávio Berwanger et al. Luiz Alberto Piva e Mattos José Fernando Vilela Martin Renato Delascio Lopes … Estevão Lanna Figueiredo Daniel Magnoni Dalton Bertolim Precoma Carlos Alberto Machado Jorge Ilha Guimarães Jadelson Pinheiro de Andrade

BACKGROUND: Data on outpatient care provided to patients at high cardiovascular risk in Brazil are insufficient. OBJECTIVE: To describe the profile and document the clinical practice of outpatient care in patients at high cardiovascular risk in Brazil, regarding the prescription of evidence-based therapies. METHODS: Prospective registry that documented the ambulatory clinical practice in individuals at high cardiovascular risk, which was defined as the presence of the following factors: coronary artery disease, cerebrovascular and peripheral vascular diseases, diabetes, or those with at least three of the following factors: hypertension, smoking, dyslipidemia, age > 70 years, family history of coronary artery disease, chronic kidney disease or asymptomatic carotid artery disease. Basal characteristics were assessed and the rate of prescription of pharmacological and non-pharmacological interventions was analyzed. RESULTS: A total of 2364 consecutive patients were included, of which 52.2% were males, with a mean age of 66.0 years (± 10.1). Of these, 78.3% used antiplatelet agents, 77.0% used statins and of patients with a history of myocardial infarction, 58.0% received beta-blockers. Concomitant use of these three classes of drugs was 34%; 50.9% of hypertensive, 67% of diabetic and 25.7% of dyslipidemic patients did not achieve the goals recommended by guidelines. The main predictors of prescription therapies with proven benefit were centers with a cardiologist and history of coronary artery disease. CONCLUSION: This national and representative registry identified important gaps in the incorporation of therapies with proven benefit, offering a realistic outlook of patients at high cardiovascular risk.

  • Cardiovascular Diseases
  • Cross-Sectional Studies
  • Drug Prescriptions
  • Mortality
  • Randomized controlled trials as topic
  • Review
  • Risk Factors
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Creative Commons Attribution (CC BY) Creative Commons license
15/04/2013 DOI: 10.5935/abc.20130062 Views 1

How to cite this article

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Electronic Document Format (Vancouver)

Berwanger O, Mattos LAP, Martin JFV, Lopes RD, Figueiredo EL, Magnoni D, Precoma DB, et al. Evidence-based therapy prescription in high-cardiovascular risk patients: the REACT study. Arquivos Brasileiros de Cardiologia 2013;100(3):212-20.

Electronic Document Format (ABNT)

Berwanger, Otávio; Mattos, Luiz Alberto Piva e; Martin, José Fernando Vilela; Lopes, Renato Delascio; Figueiredo, Estevão Lanna; Magnoni, Daniel; Precoma, Dalton Bertolim; Machado, Carlos Alberto; Guimarães, Jorge Ilha; Andrade, Jadelson Pinheiro de. Evidence-based therapy prescription in high-cardiovascular risk patients: the REACT study. Arquivos Brasileiros de Cardiologia, v. 100, n. 3, p. 212-220, Apr. 2013.

Electronic Document Format (APA)

Berwanger, O., Mattos, L. A. P. , Martin, J. F. V., Lopes, R. D., Figueiredo, E. L., Magnoni, D., Precoma, D. B., Machado, C. A., Guimarães, J. I., & Andrade, J. P. (2013). Evidence-based therapy prescription in high-cardiovascular risk patients: the REACT study. Arquivos Brasileiros de Cardiologia, 100(3), 212-220.

Electronic Document Format (ISO)

Berwanger, Otávio and Mattos, Luiz Alberto Piva e and Martin, José Fernando Vilela and Lopes, Renato Delascio and Figueiredo, Estevão Lanna and Magnoni, Daniel and Precoma, Dalton Bertolim and Machado, Carlos Alberto and Guimarães, Jorge Ilha and Andrade, Jadelson Pinheiro de. Evidence-based therapy prescription in high-cardiovascular risk patients: the REACT study. Arquivos Brasileiros de Cardiologia [online]. 2013, vol. 100, n. 3, [cited 2026-10-14], pp. 212-220. Available from: <https://journals.cardiol.br/en/article/evidence-based-therapy-prescription-in-high-cardiovascular-risk-patients-the-react-study/>. ISSN 0066-782X

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