Sílvia Marinho Martins Alves et al. Bárbara Mariana dos Santos Silva Esthefany Dias Barbosa Carolina de Araújo Medeiros … Maria das Neves Dantas da Silveira Barros Maria da Glória Aureliano de Melo Cavalcanti Maria Elisa Lucena Sales de Melo Assunção Virginia Maria Barros de Lorena Afonso Luiz Tavares de Albuquerque Renata Amorim de Lucena Carlos Eduardo Lucena Montenegro Clodoval de Barros Pereira Júnior Lucas Reis da Costa Cristina de Fátima Velloso Carrazzone Wilson de Oliveira Júnior
Abstract
Chagas disease has become globalized as a result of the migratory process of infected patients to non-endemic areas. With the considerable number of individuals affected by the disease, detection and treatment of its chronic manifestations is a relevant and necessary issue. Growing attention has been paid to chronic Chagas cardiomyopathy (CCC), which includes heart failure, malignant arrhythmias, conduction disturbances and thromboembolic events. Many pharmacological and non-pharmacological treatments for CCC are still extrapolations of existing evidence on the treatment of other clinical conditions, highlighting the need of including this group of patients in future studies. In this review, we will discuss the most recent data from the literature and clinical practice on the diagnosis and treatment of CCC.