Quantification of Myocardial Ischemia: Comparison between Myocardial SPECT and ¹³NH₃ PET/TC

Introduction

Myocardial perfusion is a very important tool to diagnose and quantify hypoperfusion related to coronary artery disease (CAD). Single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is a widely available nuclear medicine imaging tool. Cardiac ¹³N-ammonia positron emission tomography/computed tomography (¹³NH₃ PET/CT) has increased its capability to provide quantitative measures of myocardial blood flow at rest and under stress, as well as of coronary flow reserve (CFR), in addition to better image quality.

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