Cardiac involvement in total generalized lipodystrophy (Berardinelli- Seip syndrome)
Total generalized lipodystrophy (Berardinelli–Seip Syndrome) is a rare hereditary disease characterized by insulin-resistant diabetes mellitus and a small quantity of adipose tissue and is of unknown origin. Common cardiovascular alterations related to this syndrome are cardiac hypertrophy and arterial hypertension. This article reports a case of Berardinelli–Seip syndrome and reviews the literature with special emphasis on the cardiovascular manifestations of this syndrome.
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