A Rare and Fatal Association With SLE: Lutembacher Syndrome With Huge Atrial Septal Defect

Introduction

Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by periods of relapse and remission, with the potential to damage multiple organs depending on disease activity and individual susceptibility. Valvular heart disease is one of the cardiac manifestations associated with SLE. Lutembacher syndrome (LS) is an exceedingly rare clinical syndrome defined by the presence of a combination of congenital or acquired ostium secundum atrial septal defect (ASD) and congenital or acquired mitral stenosis (MS). First reported by Lutembacher in 1916, this syndrome is more frequently observed in young adults, with a higher prevalence among females. In this case report, we present the case of a young pregnant woman with SLE who visited the cardiology clinic complaining of palpitations. Eventually, she was diagnosed with LS.

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