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  • ABC Heart Failure & Cardiomyopathy
  • ABC Imagem Cardiovascular
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  2. mitral valve
IJCS
Case Report

Double-Orifice Mitral Valve with Severe Regurgitation Associated with Bicuspid Aortic Valve: A Case Report

Patricia Delgado Cedeño et al. Estefania Carolina Arteaga Herrera Cesar João Tumbaco Mite Elsie Valdivieso Valenzuela … Juan Javier Zuñiga Bohorquez Guillermo Navas Moreira

Introduction

Double-orifice mitral valve (DOMV) was first described in 1876 by the British pathologist William Smith Greenfield. It is a very rare congenital or acquired cardiac anomaly with limited epidemiologic data and no clear sex predilection.

Congenital DOMV rarely occurs in isolation and is commonly associated with other cardiac anomalies, such as aortic coarctation, patent ductus arteriosus, atrioventricular septal defects, and bicuspid aortic valve (BAV), among others. Functionally, it may behave normally and remain asymptomatic; however, symptoms may arise from mitral valve dysfunction, such as stenosis or regurgitation.

[…]

  • mitral valve
  • Mitral Valve Annuloplasty
  • Mitral Valve Insufficiency
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Creative Commons Attribution (CC BY) Creative Commons license
11/09/2026 DOI: 10.36660/ijcs.20250214 Visualizações 6
IJCS
Original Article

Women Undergoing Mitral Valve Replacement: A Retrospective Analysis

Júlia Lasserre Moreira et al. Pedro Henrique Andrade Araújo Salvatore Barletta José Augusto Baucia

Abstract

Background

Although cardiovascular disease is the leading cause of death in women, few data exist on risk factors and treatment of these diseases in women. This leads to a delay in the institution of appropriate therapies and worse outcomes in this population.

Objective

We aimed to identify predictors of morbidity and mortality in women undergoing isolated mitral valve replacement.

Methods

This was a retrospective cohort study with 104 women who underwent isolated mitral valve replacement at a referral hospital for treatment of cardiovascular diseases, performed from January 2011 to December 2016. Data were obtained from medical records. Statistical analysis was performed to calculate odds ratio, unpaired Student’s t-test, and binary logistic regression. P values <0.05 were considered statistically significant.

Results

Mean age of patients was 43.73 (±13.85) years. Most patients had a diagnosis of rheumatic disease prior to surgery (76%; N=79). Mortality rate was 4.9% (N = 5). There was a statistically higher risk of death among patients with reduced ejection fraction (EF) (<50%) (OR = 14.833, 95% CI 2.183 – 100.778, P=0.001) and older age (P = 0.009). There was an inverse association between a previous diagnosis of rheumatic disease and death (OR = 0.064, 95% CI 0.007 – 0.606, P=0.002). Logistic regression showed reduced EF at preoperative evaluation as a predictor of death and a diagnosis of rheumatic disease as a protective factor.

Conclusion

Older age and reduced EF were associated with postoperative mortality. Reduced EF was a predictor of death, and rheumatic disease was associated with better surgical outcomes.

  • mitral valve
  • Morbidity
  • Mortality
  • Thoracic Surgery
  • Women
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Creative Commons Attribution (CC BY) Creative Commons license
07/07/2021 DOI: 10.36660/ijcs.20200412 Visualizações 8
IJCS
Original Article

Bioprosthesis versus Mechanical Valve Heart Prosthesis: Assessment of Quality of Life

José Carlos Molero Junior et al. Rodrigo Daminello Raimundo, Joice Anaize Tonon do Amaral Luiz Carlos de Abreu João Roberto Breda

Abstract

Background:

The aim of this study was to evaluate the QoL of patients undergoing heart valve replacement using the SF-36 questionnaire, compare it between patients with mechanical prosthesis and patients with bioprosthesis, and correlate the results with sociodemographic variables.

Objective:

To assess the QoL of patients undergoing heart valve replacement and compare it between patients with bioprosthetic valves and patients with mechanical prosthetic valves.

Methods:

We included 36 consecutive patients (16 men) with a mean age of 51 years and six months, who underwent mitral or aortic valve replacement from September 2007 to December 2011. The study was conducted between March and May 2012 and involved the application of the SF-36 survey and a sociodemographic questionnaire. Statistical tests were performed, and data are expressed as absolute frequency and percentile, and median and interquartile range (P25 and P75) (Mann-Whitney test), considering a significance of 95%.

Results:

The average time of surgery was 32.5 months (8-61 months). Participants were asked about the practice of physical activity, and 41.7% were physically active. For the SF-36 domains, the highest scores were observed for the social domain whereas the lowest scores were found for mental health, with a mean of 89.25 and 54.44, respectively. In the statistical analysis, we found statistically higher values in emotional functional for patients with mechanical valve prosthesis (p = 0.0084).

Conclusion:

The QoL of the patients undergoing heart valve replacement improves considerably after the surgery, except for the mental health domain, probably due to the low practice of physical activity. The type of prosthesis seems not to influence the QoL or the patients in the late postoperative period.

  • Aortic Valve
  • heart valve prosthesis
  • mitral valve
  • Quality of life
  • Sickness Impact Profile
  • Stress, Psychological
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Creative Commons Attribution (CC BY) Creative Commons license
24/10/2019 DOI: 10.5935/2359-4802.20190074 Visualizações 10
ABC
Original Article

Surgical treatment of partial atrioventricular septal defect: functional analysis of the mitral valve in the postoperative period

Josué Viana Castro Neto et al. Paulo Chaccur Cláudio Leo Gelape Eliseu de Sousa Santos … Hélio Carlos Falcão Mário Issa Antoninho Sanfins Arnoni Flávio Sanches Almeida Camilo Abdulmassih Neto Jarbas Jackson Dinkhuysen Luís Carlos Bento Souza Paulo Paredes Paulista

OBJECTIVE: To study mitral valve function in the postoperative period after correction of the partial form of atrioventricular septal defect. METHODS: Fifty patients underwent surgical correction of the partial form of atrioventricular septal defect. Their mean age was 11.8 years and 62% of the patients were males. Preoperative echocardiography showed moderate and severe mitral insufficiency in 44% of the patients. The mitral valve cleft was sutured in 45 (90%) patients (group II – GII). Echocardiographies were performed in the early postoperative period, and 6 and 12 months after hospital discharge. RESULTS: The patients who had some type of arrhythmia in the postoperative period had ostium primum atrial septal defect of a larger size (2.74 x 2.08 cm). All 5 patients in group I (GI), who did not undergo closure of the cleft, had a competent mitral valve or mild mitral insufficiency in the preoperative period. One of these patients began to have moderate mitral insufficiency in the postoperative period. On the other hand, in GII, 88.8% and 82.2% of the patients had competent mitral valve or mild mitral insufficiency in the early and late postoperative periods, respectively. CONCLUSION: The mitral valve cleft was repaired in 90% of cases. Echocardiography revealed competent mitral valve or mild mitral insufficiency in 88.8% and 82.2% of GII patients in the early and late postoperative periods, respectively.

  • Cardiovascular Surgical Procedures
  • congenital heart diseases
  • mitral valve
  • partial atrioventricular septal defect
  • Surgery
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Creative Commons Attribution (CC BY) Creative Commons license
17/12/2002 DOI: 10.1590/S0066-782X2002001400002 Visualizações 6
ABC
Original Article

Percutaneous mechanical mitral commissurotomy performed with a Cribier's metallic valvulotome. Initial results

Maria Dias de Azeredo Bastos et al. César A. Esteves David Araújo Luciene Ap. M. A. Bastos … Magno Eistein Geraldo Paulino Santana Gilson José de Oliveira Luiz Brasil Antônio Calzada Delzirene Botelho Calzada José Pereira Rômulo Sales Nivaldo Gomes de Olivera

OBJECTIVE: To evaluate the immediate results of percutaneous mechanical mitral commissurotomy. METHODS: Thirty patients underwent percutaneous mechanical mitral commissurotomy performed with a Cribier’s metallic valvulotome from 8/11/99 to 2/4/00. Mean age was 30.7 years, and 73.3% were women. With regards to functional class, 63.3% were class III, and 36.7% were class IV. The echocardiographic score had a mean value of 7.5± 1.8. RESULTS: The mitral valve area increased from 0.97±0.15cm² to 2.16±0.50cm² (p>0.0001). The mean diastolic gradient decreased from 17.9±5.0mmHg to 3.2±1.4mmHg. The mean left atrial pressure decreased from 23.6±5.4mmHg to 8.6±3.1mmHg, (p>0.0001). Systolic pressure in the pulmonary artery decreased from 52.7±18.3mmHg to 32.2±7.4mmHg. Twenty-nine cases were successful. One patient developed severe mitral regurgitation. Interatrial septal defect was observed and one patient. One patient had cardiac tamponade due to left ventricular perforation. No deaths occurred. CONCLUSION: This method has proven to be safe and efficient in the treatment of rheumatic mitral stenosis. The potential advantage is that it can be used multiple times after sterilization, which decreases procedural costs significantly.

  • commissurotomy
  • metallic valvulotome
  • mitral valve
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Creative Commons Attribution (CC BY) Creative Commons license
21/08/2001 DOI: 10.1590/S0066-782X2001000800003 Visualizações 7

Como citar este artigo

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Cedeño PD, Herrera ECA, Mite CJT, Valenzuela EV, Bohorquez JJZ, Moreira GN. Double-Orifice Mitral Valve with Severe Regurgitation Associated with Bicuspid Aortic Valve: A Case Report. International Journal of Cardiovascular Sciences 2026;39:e20250214.

Formato de Documento Eletrônico (ABNT)

Cedeño, Patricia Delgado; Herrera, Estefania Carolina Arteaga; Mite, Cesar João Tumbaco; Valenzuela, Elsie Valdivieso; Bohorquez, Juan Javier Zuñiga; Moreira, Guillermo Navas. Double-Orifice Mitral Valve with Severe Regurgitation Associated with Bicuspid Aortic Valve: A Case Report. International Journal of Cardiovascular Sciences, v. 39, e20250214, set. 2026.

Formato de Documento Eletrônico (APA)

Cedeño, P. D., Herrera, E. C. A., Mite, C. J. T., Valenzuela, E. V., Bohorquez, J. J. Z., & Moreira, G. N. (2026). Double-Orifice Mitral Valve with Severe Regurgitation Associated with Bicuspid Aortic Valve: A Case Report. International Journal of Cardiovascular Sciences, 39, e20250214.

Formato de Documento Eletrônico (ISO)

Cedeño, Patricia Delgado and Herrera, Estefania Carolina Arteaga and Mite, Cesar João Tumbaco and Valenzuela, Elsie Valdivieso and Bohorquez, Juan Javier Zuñiga and Moreira, Guillermo Navas. Double-Orifice Mitral Valve with Severe Regurgitation Associated with Bicuspid Aortic Valve: A Case Report. International Journal of Cardiovascular Sciences [online]. 2026, vol. 39, [citado 2026-11-15], e20250214. Disponível em: <https://journals.cardiol.br/article/double-orifice-mitral-valve-with-severe-regurgitation-associated-with-bicuspid-aortic-valve-a-case-report-2/>. ISSN 2359-4802

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Moreira JL, Barletta PHAAS, Baucia JA. Women Undergoing Mitral Valve Replacement: A Retrospective Analysis. International Journal of Cardiovascular Sciences 2021;34(4):431-42.

Formato de Documento Eletrônico (ABNT)

Moreira, Júlia Lasserre; Barletta, Pedro Henrique Andrade Araújo Salvatore; Baucia, José Augusto. Women Undergoing Mitral Valve Replacement: A Retrospective Analysis. International Journal of Cardiovascular Sciences, v. 34, n. 4, p. 431-442, jul. 2021.

Formato de Documento Eletrônico (APA)

Moreira, J. L., Barletta, P. H. A. A. S., & Baucia, J. A. (2021). Women Undergoing Mitral Valve Replacement: A Retrospective Analysis. International Journal of Cardiovascular Sciences, 34(4), 431-442.

Formato de Documento Eletrônico (ISO)

Moreira, Júlia Lasserre and Barletta, Pedro Henrique Andrade Araújo Salvatore and Baucia, José Augusto. Women Undergoing Mitral Valve Replacement: A Retrospective Analysis. International Journal of Cardiovascular Sciences [online]. 2021, vol. 34, n. 4, [citado 2026-11-15], pp. 431-442. Disponível em: <https://journals.cardiol.br/article/women-undergoing-mitral-valve-replacement-a-retrospective-analysis-2/>. ISSN 2359-4802

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Molero Junior JC, Raimundo RD, Amaral JAT, Abreu LC, Breda JR. Bioprosthesis versus Mechanical Valve Heart Prosthesis: Assessment of Quality of Life. International Journal of Cardiovascular Sciences 2019;33(1):36-42.

Formato de Documento Eletrônico (ABNT)

Molero Junior, José Carlos; Raimundo, Rodrigo Daminello; Amaral, Joice Anaize Tonon do; Abreu, Luiz Carlos de; Breda, João Roberto. Bioprosthesis versus Mechanical Valve Heart Prosthesis: Assessment of Quality of Life. International Journal of Cardiovascular Sciences, v. 33, n. 1, p. 36-42, out. 2019.

Formato de Documento Eletrônico (APA)

Molero Junior, J. C., Raimundo, R. D., Amaral, J. A. T. , Abreu, L. C. , & Breda, J. R. (2019). Bioprosthesis versus Mechanical Valve Heart Prosthesis: Assessment of Quality of Life. International Journal of Cardiovascular Sciences, 33(1), 36-42.

Formato de Documento Eletrônico (ISO)

Molero Junior, José Carlos and Raimundo, Rodrigo Daminello and Amaral, Joice Anaize Tonon do and Abreu, Luiz Carlos de and Breda, João Roberto. Bioprosthesis versus Mechanical Valve Heart Prosthesis: Assessment of Quality of Life. International Journal of Cardiovascular Sciences [online]. 2019, vol. 33, n. 1, [citado 2026-11-15], pp. 36-42. Disponível em: <https://journals.cardiol.br/article/bioprosthesis-versus-mechanical-valve-heart-prosthesis-assessment-of-quality-of-life-2/>. ISSN 2359-4802

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Castro Neto JV, Chaccur P, Gelape CL, Santos ES, Falcão HC, Issa M, Arnoni AS, et al. Surgical treatment of partial atrioventricular septal defect: functional analysis of the mitral valve in the postoperative period. Arquivos Brasileiros de Cardiologia 2002;79(5):450-3.

Formato de Documento Eletrônico (ABNT)

Castro Neto, Josué Viana; Chaccur, Paulo; Gelape, Cláudio Leo; Santos, Eliseu de Sousa; Falcão, Hélio Carlos; Issa, Mário; Arnoni, Antoninho Sanfins; Almeida, Flávio Sanches; Abdulmassih Neto, Camilo; Dinkhuysen, Jarbas Jackson; Souza, Luís Carlos Bento; Paulista, Paulo Paredes. Surgical treatment of partial atrioventricular septal defect: functional analysis of the mitral valve in the postoperative period. Arquivos Brasileiros de Cardiologia, v. 79, n. 5, p. 450-453, dez. 2002.

Formato de Documento Eletrônico (APA)

Castro Neto, J. V., Chaccur, P., Gelape, C. L., Santos, E. S., Falcão, H. C., Issa, M., Arnoni, A. S., Almeida, F. S., Abdulmassih Neto, C., Dinkhuysen, J. J., Souza, L. C. B., & Paulista, P. P. (2002). Surgical treatment of partial atrioventricular septal defect: functional analysis of the mitral valve in the postoperative period. Arquivos Brasileiros de Cardiologia, 79(5), 450-453.

Formato de Documento Eletrônico (ISO)

Castro Neto, Josué Viana and Chaccur, Paulo and Gelape, Cláudio Leo and Santos, Eliseu de Sousa and Falcão, Hélio Carlos and Issa, Mário and Arnoni, Antoninho Sanfins and Almeida, Flávio Sanches and Abdulmassih Neto, Camilo and Dinkhuysen, Jarbas Jackson and Souza, Luís Carlos Bento and Paulista, Paulo Paredes. Surgical treatment of partial atrioventricular septal defect: functional analysis of the mitral valve in the postoperative period. Arquivos Brasileiros de Cardiologia [online]. 2002, vol. 79, n. 5, [citado 2026-11-15], pp. 450-453. Disponível em: <https://journals.cardiol.br/article/surgical-treatment-of-partial-atrioventricular-septal-defect-functional-analysis-of-the-mitral-valve-in-the-postoperative-period-2/>. ISSN 0066-782X

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Bastos MDA, Esteves CA, Araújo D, Bastos LAMA, Eistein M, Santana GP, Oliveira GJ, et al. Percutaneous mechanical mitral commissurotomy performed with a Cribier’s metallic valvulotome. Initial results. Arquivos Brasileiros de Cardiologia 2001;77(2):126-31.

Formato de Documento Eletrônico (ABNT)

Bastos, Maria Dias de Azeredo; Esteves, César A.; Araújo, David; Bastos, Luciene Ap. M. A.; Eistein, Magno; Santana, Geraldo Paulino; Oliveira, Gilson José de; Brasil, Luiz; Calzada, Antônio; Calzada, Delzirene Botelho; Pereira, José; Sales, Rômulo; Olivera, Nivaldo Gomes de. Percutaneous mechanical mitral commissurotomy performed with a Cribier’s metallic valvulotome. Initial results. Arquivos Brasileiros de Cardiologia, v. 77, n. 2, p. 126-131, ago. 2001.

Formato de Documento Eletrônico (APA)

Bastos, M. D. A., Esteves, C. A., Araújo, D., Bastos, L. A. M. A., Eistein, M., Santana, G. P., Oliveira, G. J. , Brasil, L., Calzada, A., Calzada, D. B., Pereira, J., Sales, R., & Olivera, N. G. (2001). Percutaneous mechanical mitral commissurotomy performed with a Cribier’s metallic valvulotome. Initial results. Arquivos Brasileiros de Cardiologia, 77(2), 126-131.

Formato de Documento Eletrônico (ISO)

Bastos, Maria Dias de Azeredo and Esteves, César A. and Araújo, David and Bastos, Luciene Ap. M. A. and Eistein, Magno and Santana, Geraldo Paulino and Oliveira, Gilson José de and Brasil, Luiz and Calzada, Antônio and Calzada, Delzirene Botelho and Pereira, José and Sales, Rômulo and Olivera, Nivaldo Gomes de. Percutaneous mechanical mitral commissurotomy performed with a Cribier’s metallic valvulotome. Initial results. Arquivos Brasileiros de Cardiologia [online]. 2001, vol. 77, n. 2, [citado 2026-11-15], pp. 126-131. Disponível em: <https://journals.cardiol.br/article/percutaneous-mechanical-mitral-commissurotomy-performed-with-a-cribiers-metallic-valvulotome-initial-results-2/>. ISSN 0066-782X

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