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  1. Início
  2. Palavra-chave: Hypocalcemia
IJCS
Original Article

QTc, Tp-e Interval and Tp-e/QTc Ratio in Patients with Hypocalcemia-case Control Study

Begum Seyda Avci et al. Akkan Avci Arif Aksu Muge Gulen … Onder Yesiloglu Hasan Koca Salim Satar

Abstract

Background:

To the best of our knowledge, there are studies related to QT and QTc interval in patients with hypocalcemia, but there are no studies evaluating T wave peak and end interval (Tp-e interval), Tp-e/QT and Tp-e/QTc ratios used to evaluate cardiac arrhythmia risk and ventricular repolarization changes rates.

Objectives:

Therefore, we aimed to investigate whether there is a change in Tp-e interval, Tp-e/QT and Tp-e/QTc ratios in patients with hypocalcemia.

Methods:

Retrospectively, 29 patients with hypocalcemia in the emergency department were included in the study. Twenty-nine patients with similar age and sex distribution were included in the study as the control group. All patients underwent 12-lead electrocardiography (ECG). In addition to routine measurements, Tp-e interval, Tp-e/QT and Tp-e/QTc ratios were measured on ECG. The study data were grouped as patients with and without hypocalcemia.

Results:

The mean age of the patients was 66.24 ± 4.95 years. QTc interval, Tp-e interval and Tp-e/QTc values were found to be significantly higher in patients with hypocalcemia (p <0.001 for each). QTc interval, Tp-e interval and Tp-e/QTc ratio showed a significant negative correlation with calcium levels.

Conclusion:

Tp-e interval and Tp-e/QTc ratios are significantly increased in patients with hypocalcemia compared to those without hypocalcemia and this can be used more effectively in the follow-up of cardiac fatal arrhythmias.

  • Hypocalcemia
  • QTc
  • Tp-e interval
  • Tp-e/QTc ratio
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Creative Commons Attribution (CC BY) Creative Commons license
28/04/2021 DOI: 10.36660/ijcs.20200216 Visualizações 1
IJCS
Case Report

Cardiac Arrest Due to Hypocalcemia

Fernanda Aburesi Salvadori et al. Eduardo Martelli Moreira Murilo Bacchini Dias Amaro Nunes Duarte-Neto Edison Ferreira de Paiva

Discussion

Long QT syndrome (LQTS) can be congenital or acquired. The causes of acquired LQTS include hypocalcemia, due to prolongation of the phase 2 of the action potential (AP), medications (amiodarone, antidepressants and neuroleptics), hypokalemia, hypomagnesemia and severe bradycardia. – LQTS is associated with a specific polymorphic ventricular tachycardia (VT), named as torsades de pointes (TdP), because of the characteristic shift in the QRS axis that gives the impression of a “torsion”.

The QT interval is a marker of the AP duration. In LQTS patients, the AP is prolonged unevenly across the myocardium, so as to cause high dispersion of repolarization. The AP prolongation favors the formation of early afterdepolarization (EAD), which are deformities in the plateau and rapid repolarization phases (2 and 3) capable of inducing ventricular extrasystoles. EADs in the unevenly repolarized myocardium are the cause of TdP. Tachycardia is sustained due to focal electric activity and/or a reentrant mechanism. It may either cease spontaneously or degenerate into ventricular fibrillation and cardiac arrest , .

[…]

  • Cardiopulmonary Resuscitation
  • Heart Arrest
  • Hypertension
  • Hypocalcemia
  • Kidney Transplantation
  • renal dialysis
  • Renal Insufficiency
  • Tachycardia Ventricular
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Creative Commons Attribution (CC BY) Creative Commons license
23/11/2020 DOI: 10.36660/ijcs.20200034

Como citar este artigo

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Avci BS, Avci A, Aksu A, Gulen M, Yesiloglu O, Koca H, Satar S, et al. QTc, Tp-e Interval and Tp-e/QTc Ratio in Patients with Hypocalcemia-case Control Study. International Journal of Cardiovascular Sciences 2021;34(5 Supl 1):87-94.

Formato de Documento Eletrônico (ABNT)

Avci, Begum Seyda; Avci, Akkan; Aksu, Arif; Gulen, Muge; Yesiloglu, Onder; Koca, Hasan; Satar, Salim. QTc, Tp-e Interval and Tp-e/QTc Ratio in Patients with Hypocalcemia-case Control Study. International Journal of Cardiovascular Sciences, v. 34, n. 5 Supl 1, p. 87-94, abr. 2021.

Formato de Documento Eletrônico (APA)

Avci, B. S., Avci, A., Aksu, A., Gulen, M., Yesiloglu, O., Koca, H., & Satar, S. (2021). QTc, Tp-e Interval and Tp-e/QTc Ratio in Patients with Hypocalcemia-case Control Study. International Journal of Cardiovascular Sciences, 34(5 Supl 1), 87-94.

Formato de Documento Eletrônico (ISO)

Avci, Begum Seyda and Avci, Akkan and Aksu, Arif and Gulen, Muge and Yesiloglu, Onder and Koca, Hasan and Satar, Salim. QTc, Tp-e Interval and Tp-e/QTc Ratio in Patients with Hypocalcemia-case Control Study. International Journal of Cardiovascular Sciences [online]. 2021, vol. 34, n. 5 Supl 1, [citado 2026-10-14], pp. 87-94. Disponível em: <https://journals.cardiol.br/article/qtc-tp-e-interval-and-tp-e-qtc-ratio-in-patients-with-hypocalcemia-case-control-study-2/>. ISSN 2359-4802

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Salvadori FA, Moreira EM, Dias MB, Duarte-Neto AN, Paiva EF. Cardiac Arrest Due to Hypocalcemia. International Journal of Cardiovascular Sciences 2020;34(5 Supl 1):154-7.

Formato de Documento Eletrônico (ABNT)

Salvadori, Fernanda Aburesi; Moreira, Eduardo Martelli; Dias, Murilo Bacchini; Duarte-Neto, Amaro Nunes; Paiva, Edison Ferreira de. Cardiac Arrest Due to Hypocalcemia. International Journal of Cardiovascular Sciences, v. 34, n. 5 Supl 1, p. 154-157, nov. 2020.

Formato de Documento Eletrônico (APA)

Salvadori, F. A., Moreira, E. M., Dias, M. B., Duarte-Neto, A. N., & Paiva, E. F. (2020). Cardiac Arrest Due to Hypocalcemia. International Journal of Cardiovascular Sciences, 34(5 Supl 1), 154-157.

Formato de Documento Eletrônico (ISO)

Salvadori, Fernanda Aburesi and Moreira, Eduardo Martelli and Dias, Murilo Bacchini and Duarte-Neto, Amaro Nunes and Paiva, Edison Ferreira de. Cardiac Arrest Due to Hypocalcemia. International Journal of Cardiovascular Sciences [online]. 2020, vol. 34, n. 5 Supl 1, [citado 2026-10-14], pp. 154-157. Disponível em: <https://journals.cardiol.br/article/cardiac-arrest-due-to-hypocalcemia-2/>. ISSN 2359-4802

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