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  2. Palavra-chave: Cross-Sectional Studies
IJCS
Original Article

Reliability between Cardiovascular Risk Assessment Tools: A Pilot Study

Rodrigo Conill Marasciulo et al. Ana Maria Nunes de Faria Stamm Guilherme Thomé Garcia Antônio Carlos Estima Marasciulo … Ariel Córdova Rosa Alexandre Augusto de Costa Remor Cristian Battistella

Abstract

Background

The prevention of cardiovascular disease (CVD) is important in clinical practice due to its high morbidity and mortality. Different guidelines have recommended the use of different cardiovascular risk assessment tools, which may have implications on therapeutic decisions.

Objective

To evaluate the agreement rate between the Framingham risk score (FRS) and the Systematic Coronary Risk Evaluation (SCORE) tool on CVD risk assessment in disease-free subjects.

Methods

Cross-sectional study with a sample of 51 subjects treated at the outpatient clinic of a university hospital in Brazil between January 2014 and January 2015. The FRS and two versions of the European SCORE (SCORE-High and SCORE-Low) were used to assess CVD risk; patients were classified as low/moderate risk (< 20% and <5%, respectively) or high risk (≥ 20% and ≥5%, respectively). The agreement rate was evaluated using kappa statistics, a test for interrater reliability that ranges from -1 to 1, and results above 0.6 represent a high agreement rate.

Results

The FRS classified a higher proportion of subjects as high risk for CVD (35.3% [18/51] vs. 23.5% [12/51] with the SCORE-High and 13.7% [7/51] with SCORE-Low). However, there was a high agreement rate between FRS and SCORE-High (k=0.628). The agreement between FRS and SCORE-Low was poor (k=0.352).

Conclusions

There was a high agreement rate between FRS and SCORE-High in cardiovascular risk assessment in the study sample. (Int J Cardiovasc Sci. 2020; [online].ahead print, PP.0-0)

  • Cardiovascular Diseases/prevention and control
  • Cross-Sectional Studies
  • diabetes
  • Hypertension
  • Morbidity
  • Mortality
  • Risk Assessment
  • Risk Factors
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Creative Commons Attribution (CC BY) Creative Commons license
07/07/2020 DOI: 10.36660/ijcs.20190157 Visualizações 1
IJCS
Original Article

Cardiovascular Disease in Patients with Ankylosing Spondylitis from the Rheumatology Outpatient Clinic of the UFMS-affiliated Hospital

Delcio Gonçalves da Silva Junior et al. Izaias Pereira da Costa

Abstract

Background:

Cardiovascular diseases are a major cause of morbidity and mortality today. Despite its wide distribution, it presents particularly prevalent in certain groups of individuals, particularly when exposed to a higher degree of inflammation, giving increased cardiovascular risk. Rheumatic diseases expose their holders to this increased cardiovascular risk condition; however only recently have been associated with spondyloarthritis, particularly ankylosing spondylitis (AS). For being a classically autoimmune disease related to HLA histocompatibility system, AS may present phenotypic variations in different ethnic groups with possible diverse cardiovascular consequences.

Objectives:

To estimate the prevalence of cardiovascular disease (CVD) and the cardiovascular risk profile, correlating the time since diagnosis and activity of ankylosing spondylitis (AS) in patients from the rheumatology outpatient clinic of the UFMS-affiliated hospital.

Methods:

Of 55 patients with AS, 42 were selected consecutively and compared to a control group (CG) in a cross-sectional study. Patients with diabetes, indigenous background and pregnant women were excluded. Quantitative variables were assessed by use of Student t test, while qualitative variables, by chi-square test. The patients underwent electrocardiography, echocardiography and carotid Doppler examination, measurement of serum lipid levels and inflammatory markers, and were stratified according to global cardiovascular risk. The AS activity and impairment were evaluated by use of the BASMI, BASDAI, BASFI and ASDAS.

Results:

Mean age, 42.87 ± 12.37 years; time since AS diagnosis, 10.76 ± 8.74 years. There was no difference in cardiovascular risk stratification between the groups, most of the patients being at high or moderate risk (AS: 64.3%, and CG: 52%, p = 0.134). The prevalence of manifest CVD (2%) showed no difference between the groups, except for right bundle-branch block (AS: 14%, and CG: 2%, p = 0.027). The prevalence of subclinical CVD showed no difference between the groups, except for higher carotid medial-intimal thickness (CIMT) in the AS group (AS: 1.82 ± 2.63, and CG: 0.67 ± 0.16, p = 0.018). There was no correlation between AS activity or inflammatory markers and CVD, but with time since AS diagnosis and CIMT (p = 0.039, r = 0.328).

Conclusions:

Prevalence of CVD and risk factors was similar in the groups. Subclinical atherosclerosis degree was higher in the AS group, related to the time since diagnosis, but was independent of the cardiovascular risk factors or inflammation. Most patients with AS are at high cardiovascular risk.

  • cardiovascular diseases
  • Cross-Sectional Studies
  • Risk Factors
  • Spondylitis, Ankylosing / complications
  • Spondylitis, Ankylosing / diagnosis
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Creative Commons Attribution (CC BY) Creative Commons license
01/01/2019 DOI: 10.5935/2359-4802.20180076

Como citar este artigo

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Marasciulo RC, Stamm AMNF, Garcia GT, Marasciulo ACE, Rosa AC, Remor AAC, Battistella C, et al. Reliability between Cardiovascular Risk Assessment Tools: A Pilot Study. International Journal of Cardiovascular Sciences 2020;33(6):618-26.

Formato de Documento Eletrônico (ABNT)

Marasciulo, Rodrigo Conill; Stamm, Ana Maria Nunes de Faria; Garcia, Guilherme Thomé; Marasciulo, Antônio Carlos Estima; Rosa, Ariel Córdova; Remor, Alexandre Augusto de Costa; Battistella, Cristian. Reliability between Cardiovascular Risk Assessment Tools: A Pilot Study. International Journal of Cardiovascular Sciences, v. 33, n. 6, p. 618-626, jul. 2020.

Formato de Documento Eletrônico (APA)

Marasciulo, R. C., Stamm, A. M. N. F., Garcia, G. T., Marasciulo, A. C. E., Rosa, A. C., Remor, A. A. C., & Battistella, C. (2020). Reliability between Cardiovascular Risk Assessment Tools: A Pilot Study. International Journal of Cardiovascular Sciences, 33(6), 618-626.

Formato de Documento Eletrônico (ISO)

Marasciulo, Rodrigo Conill and Stamm, Ana Maria Nunes de Faria and Garcia, Guilherme Thomé and Marasciulo, Antônio Carlos Estima and Rosa, Ariel Córdova and Remor, Alexandre Augusto de Costa and Battistella, Cristian. Reliability between Cardiovascular Risk Assessment Tools: A Pilot Study. International Journal of Cardiovascular Sciences [online]. 2020, vol. 33, n. 6, [citado 2026-10-14], pp. 618-626. Disponível em: <https://journals.cardiol.br/article/reliability-between-cardiovascular-risk-assessment-tools-a-pilot-study-2/>. ISSN 2359-4802

EndNote RIS

Formato de Documento Eletrônico (Vancouver)

Silva Junior DG, Costa IP. Cardiovascular Disease in Patients with Ankylosing Spondylitis from the Rheumatology Outpatient Clinic of the UFMS-affiliated Hospital. International Journal of Cardiovascular Sciences 2019;32(1):10-8.

Formato de Documento Eletrônico (ABNT)

Silva Junior, Delcio Gonçalves da; Costa, Izaias Pereira da. Cardiovascular Disease in Patients with Ankylosing Spondylitis from the Rheumatology Outpatient Clinic of the UFMS-affiliated Hospital. International Journal of Cardiovascular Sciences, v. 32, n. 1, p. 10-18, dez. 2018.

Formato de Documento Eletrônico (APA)

Silva Junior, D. G. , & Costa, I. P. (2019). Cardiovascular Disease in Patients with Ankylosing Spondylitis from the Rheumatology Outpatient Clinic of the UFMS-affiliated Hospital. International Journal of Cardiovascular Sciences, 32(1), 10-18.

Formato de Documento Eletrônico (ISO)

Silva Junior, Delcio Gonçalves da and Costa, Izaias Pereira da. Cardiovascular Disease in Patients with Ankylosing Spondylitis from the Rheumatology Outpatient Clinic of the UFMS-affiliated Hospital. International Journal of Cardiovascular Sciences [online]. 2019, vol. 32, n. 1, [citado 2026-10-14], pp. 10-18. Disponível em: <https://journals.cardiol.br/article/cardiovascular-disease-in-patients-with-ankylosing-spondylitis-from-the-rheumatology-outpatient-clinic-of-the-ufms-affiliated-hospital-2/>. ISSN 2359-4802

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