Resistance to Loop Diuretics: How to Address it in the Current Scenario?

Conclusion

Resistance to diuretics is a frequent reality in many patients with HF and is associated with a worse prognosis. Several recent studies have addressed this problem by seeking alternative treatments for LD, either with more frequent monitoring or using natriuresis to help when combining diuretics. It is always important to seek the treatment of congestion with adequate doses of LD, association with SGLT2 inhibitors and, in refractory cases, consider the association of other classes of diuretics such as acetazolamide or thiazides.

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