How to Evaluate Cardiac Autonomic Modulation
Cardiac autonomic nervous system dysfunction has been implicated in several different pathological scenarios with a wide range of clinical relevance and risk. Early detection of autonomic changes, either provoked for therapeutic purposes or as a complication of a primary disorder, such as diabetes mellitus (DM) is of essence for the best management of patients.
Classic (linear) analysis of heart rate variability (HRV) has been routinely used to assess autonomic behavior in diabetic patients in order to promptly detect neuropathy, one of the most common and overlooked complications and a significant cardiovascular risk factor.
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