Coronary CT Angiography in Asymptomatic Patients: Is There Evidence For Using It?

Abstract

Cardiovascular diseases are the leading cause of death worldwide, and their clinical management is complicated by 3 main pathophysiological factors: a) a long onset period, often decades before a clinical event; b) a silent clinical course; and c) a multifactorial and heterogeneous pathogenesis among different population subgroups. Coronary CT angiography is the best available tool for diagnosing and phenotyping coronary artery disease, whether obstructive or non-obstructive. This allows early diagnosis and monitoring of the disease, which is essential for deciding who should be treated, determining the therapeutic approach, and for better patient adherence to clinical treatment. Early and accurate diagnosis generally results in better clinical outcomes.