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Swim training attenuates myocardial remodeling and the pulmonary congestion in wistar rats with secondary heart failure to myocardial infarction
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Swim training attenuates myocardial remodeling and the pulmonary congestion in wistar rats with secondary heart failure to myocardial infarction

Leslie Andrews Portes et al. Paulo José Ferreira Tucci

OBJECTIVE: To evaluate the effects of swimming on pulmonary water content in animals with heart failure (HF) after myocardial infarction (MI). METHODS: After coronary occlusion, MI size 20%<MI 40% of the LV large. The animals swam for 60 min/day, 5 days/week for 8 weeks. The wet weight of lung, liver, atriums, LV and right ventricle (RV) as well as the dry weight of the liver and lung were determined. ANOVA and Tukey test were used for statistical analysis. RESULTS: An increase in the atrium/body weight ratio was noted in the sedentary animals with moderate (MImod-SED: n=8) and large (MIlg-SED: n=10) infarctions in comparison to the sedentary control (C-SED: n=14) and trained (C-TR: n=16) rats. An increase in the RV/body weight and LV/body weight ratios was noted in the MIlg-SED. The heart/body weight ratio was higher in MIlg-SED when compared to the other groups. The infarcted trained animals presented diminished hypertrophy. The pulmonary water content was higher in MIlg-SED animals (81±0.4%) than in C-SED animals (79±0.4%). No differences were found for the other comparisons (C-TR: 79±0.4%; MImod-SED: 80±0.3%; MImod-TR: 80±0.6%; MIlg-TR: 79±0.7%). CONCLUSION: The increase of cardiac mass and pulmonary water content presented by MIlg-SED was diminished in the trained animals. The results suggest that the practice of physical exercise can diminish HF and contribute to favorable cardiac remodeling.

  • myocardial hypertrophy
  • Myocardial Infarction
  • Rats
  • swimming pulmonary water content
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Creative Commons Attribution (CC BY) Creative Commons license
28/07/2006 DOI: 10.1590/S0066-782X2006001400008 Views 1

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Portes LA, Tucci PJF. Swim training attenuates myocardial remodeling and the pulmonary congestion in wistar rats with secondary heart failure to myocardial infarction. Arquivos Brasileiros de Cardiologia 2006;87(1):54-9.

Electronic Document Format (ABNT)

Portes, Leslie Andrews; Tucci, Paulo José Ferreira. Swim training attenuates myocardial remodeling and the pulmonary congestion in wistar rats with secondary heart failure to myocardial infarction. Arquivos Brasileiros de Cardiologia, v. 87, n. 1, p. 54-59, Jul. 2006.

Electronic Document Format (APA)

Portes, L. A., & Tucci, P. J. F. (2006). Swim training attenuates myocardial remodeling and the pulmonary congestion in wistar rats with secondary heart failure to myocardial infarction. Arquivos Brasileiros de Cardiologia, 87(1), 54-59.

Electronic Document Format (ISO)

Portes, Leslie Andrews and Tucci, Paulo José Ferreira. Swim training attenuates myocardial remodeling and the pulmonary congestion in wistar rats with secondary heart failure to myocardial infarction. Arquivos Brasileiros de Cardiologia [online]. 2006, vol. 87, n. 1, [cited 2026-10-14], pp. 54-59. Available from: <https://journals.cardiol.br/en/article/swim-training-attenuates-myocardial-remodeling-and-the-pulmonary-congestion-in-wistar-rats-with-secondary-heart-failure-to-myocardial-infarction/>. ISSN 0066-782X

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