stability – ABC CARDIOL

ABC

Editorial

Beetroot Juice May Be a Dietary Ingredient to Protect Vascular Endothelium

The first Dietary Recommendations originated in 1941 by order of President Franklin Roosevelt, when he convened the “National Conference on Nutrition in Defense” to guarantee a population fit for war, minimizing diseases due to deficiency of nutrients.In the same year, the American Medical Association declared that “nutrition research should be encouraged” with primary objectives of “estimating the amounts of essential nutrients in foods,” “detection of nutritional deficiency states,” and more precise determination of “optimal and minimum requirements” for each nutrient.

In humans, after absorption through the stomach wall, 25% of the nitrate consumed enters the entero-salivary circulation, where it is reduced to nitrite (NO₂) by bacterial nitrate reductases of facultative anaerobes on the dorsal surface of the tongue.^,This nitrite is swallowed and, in the stomach’s acidic environment, is reduced to nitric oxide (NO) or re-enters the circulation as nitrite. Thus, dietary nitrate may represent an intravascular source of the pleiotropic vasoprotective molecule NO and acts as a potent dilator of blood pressure and delays atherogenesis by inhibiting the recruitment of inflammatory cells and platelet aggregation. Thus, protecting the vascular endothelium influences numerous cardiovascular pathologies (prehypertension, hypertension, atherosclerosis, and stroke) associated with endothelial dysfunction and decreased NObioactivity. Recently, studies have shown that nitrite confers marked protection against ischemia/reperfusion (I/R) injury to the myocardium, kidney, lung, and cerebral vasculature.^,

[…]

Read Full Article

ABC

Artigo Original

Reliability of brachial artery flow-mediated dilatation measurement using ultrasound

Cláudia de Mello Meirelles et al. Sandra Pereira Leite Carlos Antonio Barbosa Montenegro Paulo Sergio Chagas Gomes

OBJECTIVE: To determine the reliability of the baseline (BBAB) and post occlusion (POBAD) brachial artery diameters, brachial artery flow-mediated dilatations (BAFMD) measurements, and to quantify the typical error of the measurements (TEM). METHODS: Internal consistency (2 measurements on the same day) was determined in 10 volunteers, whereas stability (2 measurements on separate days) was determined in 13 volunteers. All the volunteers looked healthy and were nonsmokers. The brachial artery images were obtained using a two dimensional Doppler ultrasound instrument: a 14 MHz transducer was used. The distances between the intima-lumen interfaces were measured before and after the blood flow had been stopped by means of a cuff on the arm for five minutes. BAFMD was considered as the percentile increase of POBAD in relation to BBAD. RESULTS: ANOVA did not identify any significant differences between the measurements taken on the same and separate days. For BAFMD, the intraclass correlation coefficients between the measurements taken on the same and separate days were: R = 0.7001 and R = 0.8420, respectively (p < 0.05). The variation coefficients were 5.8% and 12.4% and the relative SMEs were 13.8% and 14.9%, respectively, for the measurements taken on the same and separate days. Analysis of the Bland-Altman graphs indicated that the variables did not present heteroscedastic errors. CONCLUSION: The BBAD, POBAD and BAFMD measurements using the manual ultrasound technique were highly reliable for both the same and separate day measurements and therefore can be used to diagnose and monitor endothelial function.

Read Full Article

Beetroot Juice May Be a Dietary Ingredient to Protect Vascular Endothelium

Reliability of brachial artery flow-mediated dilatation measurement using ultrasound

Electronic Document Format (Vancouver)

Electronic Document Format (ABNT)

Electronic Document Format (APA)

Electronic Document Format (ISO)

Electronic Document Format (Vancouver)

Electronic Document Format (ABNT)

Electronic Document Format (APA)

Electronic Document Format (ISO)