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Chagas heart disease and contractility rate responsive pacing controlled by autonomic nervous system variations

Oswaldo Tadeu Greco et al. Roberto Vito Ardito Dorotéia Rossi Silva Souza Max Schaldach

PURPOSE: To analyse the performance of the artificial cardiac stimulation with the VVIR pacemaker whose sensor is adjusted by the variations of the autonomic nervous system in Chagas disease patients with deficiency of the conduction system. METHODS: Forty-seven Chagas disease patients have been studied, 28 male between 24 and 68 years old, 36 patients had complete AV block, 8 had 2nd degree AV block and the other 3 had sinus node disease. The patients were in class I (4), II (15), III (16) and IV (12) according to the NYHA. A 12-month-follow-up with constant clinical evaluations was carried out after pacemaker implantation. Patients were divided in 2 different groups according to the HR at rest – group 1: >65 beats per minute (bpm) and group 2: <=65bpm, for a comparative study considering: 1) HR at stress test after the implantation; 2) arterial blood pressure at rest after the implantation and, 3) evaluation of the identified electrodes such as TIR-60-UP and others. RESULTS: The group 1 had greater HR at rest, and a smaller variation of values at stress than group 2. This shows that with this type of stimulation system it is possible to control each patient separately. The values of blood pressure at rest and during stress were not different between groups. According to the factors analysed the TIR-60-UP electrode had the same performance as the others. CONCLUSION: The VVIR pacemaker with the sensor adjusted by the ANS variations has provided the Chagas patients with a restoration of their physiological mechanisms. 74% of them had the improvement of either one or 2 functional classes.

  • Autonomic Nervous System
  • Chagas disease
  • pacing
  • rate responsive pacing
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Creative Commons Attribution (CC BY) Creative Commons license
08/01/2002 DOI: 10.1590/S0066-782X1998001200004 Views 1

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Greco OT, Ardito RV, Souza DRS, Schaldach M. Chagas heart disease and contractility rate responsive pacing controlled by autonomic nervous system variations. Arquivos Brasileiros de Cardiologia 2002;71(6):751-6.

Electronic Document Format (ABNT)

Greco, Oswaldo Tadeu; Ardito, Roberto Vito; Souza, Dorotéia Rossi Silva; Schaldach, Max. Chagas heart disease and contractility rate responsive pacing controlled by autonomic nervous system variations. Arquivos Brasileiros de Cardiologia, v. 71, n. 6, p. 751-761, Jan. 2002.

Electronic Document Format (APA)

Greco, O. T., Ardito, R. V., Souza, D. R. S., & Schaldach, M. (2002). Chagas heart disease and contractility rate responsive pacing controlled by autonomic nervous system variations. Arquivos Brasileiros de Cardiologia, 71(6), 751-761.

Electronic Document Format (ISO)

Greco, Oswaldo Tadeu and Ardito, Roberto Vito and Souza, Dorotéia Rossi Silva and Schaldach, Max. Chagas heart disease and contractility rate responsive pacing controlled by autonomic nervous system variations. Arquivos Brasileiros de Cardiologia [online]. 2002, vol. 71, n. 6, [cited 2026-10-14], pp. 751-761. Available from: <https://journals.cardiol.br/en/article/chagas-heart-disease-and-contractility-rate-responsive-pacing-controlled-by-autonomic-nervous-system-variations/>. ISSN 0066-782X

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