Environmental Pollutants

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Original Article

Effects of Air Pollutant Exposure on Acute Myocardial Infarction, According to Gender

Tássia Soldi Tuan et al. Taís Siqueira Venâncio Luiz Fernando Costa Nascimento

Abstract

Background:

There is evidence of the effects of air pollution on hospital admissions due to cardiovascular diseases, including myocardial infarction.

Objective:

To estimate the association between exposure to air pollutants and hospital admissions due to myocardial infarction according to gender, between January 1^st 2012 and December 31^st 2013, in São Jose dos Campos-SP.

Methods:

An ecological time series study was carried out with daily data of admissions due to AMI, pollutants CO, O₃, PM₁₀, SO₂, and NO₂, according to gender. We used the Poisson regression generalized linear model to estimate the relative risks of hospital admissions with lags of 0-5 days, adjusted for temperature, humidity, seasonality and days of the week.

Results:

There were 1837 admissions for ischemic heart diseases, with 636 women and 1201 men. For females, the risks were significant for CO in lag 0 (RR = 1,09), lag1 (RR = 1,08) and lag 5 (RR = 1,10) and SO₂ in lag 0 (RR = 1,10) and 3 (RR = 1,09). For men there was significance of the CO in, lag 3 and lag 5 (RR = 1,05). There was significance, regardless of gender, for CO at lag 1 (RR = 1,05) and lag 5 (RR = 1,07) and lag 0 for SO₂ (RR = 1,06).

Conclusion:

The data presented show the important role of CO and SO₂ in the genesis of myocardial infarction admissions, and responses to pollutant exposure are different if analyzed by gender and together – hence the importance of a stratified analyses.

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Effects of Air Pollutant Exposure on Acute Myocardial Infarction, According to Gender

Abstract

Background:

Objective:

Methods:

Results:

Conclusion:

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