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Validating Artificial Intelligence before the Bedside: ChatGPT-4 vs Mini in Guideline-Based Hypertension Content

Cláudio Tinoco Mesquita et al. Fernanda Azevedo Silva Ana Beatriz Costa do Couto

The rapid integration of artificial intelligence (AI) into medical practice is a reality. From clinical decision support and study design to chatbot tools and the production of educational materials, large language models (LLMs) are increasingly used in daily practice. In this context, studies like the study of Ataídes et al., evaluating the performance of LLM-based materials, are crucial.

Hypertension is one of the leading causes of premature death; therefore, the World Health Organization (WHO) invests in prevention campaigns. It is a disease that affects multiple organs, causing a major impact on the entire body. The condition is defined by a systolic blood pressure (BP) of 140 mmHg or higher, or a diastolic BP of 90 mmHg, according to Brazilian Society of Cardiology guidelines. The number of individuals diagnosed with hypertension increases each year, and studies indicate that the population’s eating habits are characterized by high consumption of ultra-processed foods.

[…]

  • Artificial Intelligence
  • ChatGPT
  • Clinical Guidelines
  • Hypertension
  • validation
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Creative Commons Attribution (CC BY) Creative Commons license
05/06/2026 DOI: 10.36660/abc.20260254i Views 4

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Mesquita CT, Silva FA, Couto ABC. Validating Artificial Intelligence before the Bedside: ChatGPT-4 vs Mini in Guideline-Based Hypertension Content. Arquivos Brasileiros de Cardiologia 2026;123(2):e20260254.

Electronic Document Format (ABNT)

Mesquita, Cláudio Tinoco; Silva, Fernanda Azevedo; Couto, Ana Beatriz Costa do. Validating Artificial Intelligence before the Bedside: ChatGPT-4 vs Mini in Guideline-Based Hypertension Content. Arquivos Brasileiros de Cardiologia, v. 123, n. 2, e20260254, Jun. 2026.

Electronic Document Format (APA)

Mesquita, C. T., Silva, F. A., & Couto, A. B. C. (2026). Validating Artificial Intelligence before the Bedside: ChatGPT-4 vs Mini in Guideline-Based Hypertension Content. Arquivos Brasileiros de Cardiologia, 123(2), e20260254.

Electronic Document Format (ISO)

Mesquita, Cláudio Tinoco and Silva, Fernanda Azevedo and Couto, Ana Beatriz Costa do. Validating Artificial Intelligence before the Bedside: ChatGPT-4 vs Mini in Guideline-Based Hypertension Content. Arquivos Brasileiros de Cardiologia [online]. 2026, vol. 123, n. 2, [cited 2026-10-14], e20260254. Available from: <https://journals.cardiol.br/en/article/validating-artificial-intelligence-before-the-bedside-chatgpt-4-vs-mini-in-guideline-based-hypertension-content/>. ISSN 0066-782X

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