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  2. Keyword: Cells Proliferation
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Editorial

PTEN in the Context of Myocardial Revascularization: The Iceberg Tip?

Leonardo Rufino Garcia et al. André Monti Garzesi Marcello Laneza Felicio Leonardo Antônio Mamede Zornoff

Cardiovascular diseases significantly contribute to morbidity and mortality in Brazil and worldwide. Within this group of diseases, coronary artery disease stands out, accounting for about 12% of total deaths in Brazil and is a leading cause of death in North America.

In addition to lifestyle changes such as smoking cessation, weight loss with regular physical activity, control of comorbidities, notably diabetes and arterial hypertension, and drug treatment with antiplatelet agents, beta-blockers, and statins, a significant number of patients require treatment aimed at myocardial revascularization. Diabetic, multivessel-diseased patients with obstructions in the left main coronary artery greater than 50% or with depressed left ventricular function benefit the most. This fact is due to different factors, including a decrease in ischemia and symptoms, an improvement in quality of life, a decrease in the occurrence of infarcts, and, above all, mortality improvement.

[…]

  • Apoptosis
  • Cardiovascular Diseases
  • Cells Proliferation
  • Coronary Artery Disease/surgery
  • Glycolysis
  • Lipogenesis
  • Myocardial Revascularization/surgery
  • Phosphatidyglinositol-3 Kinases/metabolism
  • PTEN-Phosphohydrolase
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Creative Commons Attribution (CC BY) Creative Commons license
07/04/2023 DOI: 10.36660/abc.20230170

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Garcia LR, Garzesi AM, Felicio ML, Zornoff LAM. PTEN in the Context of Myocardial Revascularization: The Iceberg Tip?. Arquivos Brasileiros de Cardiologia 2023;120(4):e20230170.

Electronic Document Format (ABNT)

Garcia, Leonardo Rufino; Garzesi, André Monti; Felicio, Marcello Laneza; Zornoff, Leonardo Antônio Mamede. PTEN in the Context of Myocardial Revascularization: The Iceberg Tip?. Arquivos Brasileiros de Cardiologia, v. 120, n. 4, e20230170, Apr. 2023.

Electronic Document Format (APA)

Garcia, L. R., Garzesi, A. M., Felicio, M. L., & Zornoff, L. A. M. (2023). PTEN in the Context of Myocardial Revascularization: The Iceberg Tip?. Arquivos Brasileiros de Cardiologia, 120(4), e20230170.

Electronic Document Format (ISO)

Garcia, Leonardo Rufino and Garzesi, André Monti and Felicio, Marcello Laneza and Zornoff, Leonardo Antônio Mamede. PTEN in the Context of Myocardial Revascularization: The Iceberg Tip?. Arquivos Brasileiros de Cardiologia [online]. 2023, vol. 120, n. 4, [cited 2026-10-14], e20230170. Available from: <https://journals.cardiol.br/en/article/pten-in-the-context-of-myocardial-revascularization-the-iceberg-tip/>. ISSN 0066-782X

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