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Ventricular resynchronization through biventricular cardiac pacing for the treatment of refractory heart failure in dilated cardiomyopathy
ABC
Original Article

Ventricular resynchronization through biventricular cardiac pacing for the treatment of refractory heart failure in dilated cardiomyopathy

Silas S. Galvão Fº et al. Cecília M. B. Barcellos J. Tarcísio M. Vasconcelos Jaime G. M. Arnez … Kátia N. Couceiro Leudo Campos Evandro Sbaraini Maurício G. Lyra Fernando S. O. Souza

OBJECTIVE: The biventricular pacing (BVP) approach has good results in the treatment of congestive heart failure (CHF) in patients (pts) with disorders of intraventricular conduction. METHODS: We have applied BVP to 28 pts, with left ventricular pacing using minitoracotomy in 3 pts and the transvenous aproach via coronary sinus in 25 pts. The mean duration of the QRS complexes was 187 ms, in the presence of the left branch block in 22 pts, and right branch block + divisional hemiblock in 6 pts. All pts had been considerated candidates to cardiac transplantation, and were under optimized drug therapy. Sixteen pts were in Functional Class (NYHA) IV, and 12 in class III. The ejection fraction varied from 22 to 46% (average = 34%). The pacing mode employed was biventricular triple-chamber in 22 pts, and bi-ventricular dual-chamber in 6 pts (one with ICD). RESULTS: The pts were followed up for a period that ranged from 10 days to 14 months (mean 5 months). All pts presented clinical improvement after implant, chaging the NYHA Functional Class at the end of follow-up to Class I (9pts), Class II (10 pts) and Class III (6 pts). The initial mean ejection fraction have-raised to 37%. Two pts died suddenly. One patient died due to a pulmonary fungal infection. CONCLUSION: Ventricular resynchronization through BVP, improved significantly the Functional Class and, therefore, the quality of life. Assessments of myocardial function acutely performed do not reflect the clinical improvement observed.

  • biventricular pacing
  • Heart Failure
  • ventricular resynchronization
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Creative Commons Attribution (CC BY) Creative Commons license
19/02/2002 DOI: 10.1590/S0066-782X2002000100004 Views 1
ABC
Original Article

Biventricular pacing improves clinical behavior and reduces prevalence of ventricular srrhythmia in patients with heart failure

Martino Martinelli Filho et al. Anísio A. A. Pedrosa Roberto Costa Silvana A. D. Nishioka … Sérgio F. Siqueira Wagner T. Tamaki Eduardo Sosa

PURPOSE: To analyze the influence of biventricular pacing (BP) on clinical behavior, ventricular arrhythmia (VA) prevalence, and left ventricular ejection fraction (LV EF) by gated ventriculography. METHODS: Twenty-four patients with left bundle branch block (LBBB) and NYHA class III and IV underwent pacemaker implantation and were randomized either to the conventional or BP group, all receiving BP after 6 months. RESULTS: Sixteen patients were in NYHA class IV (66.6%) and 8 were in class III (33.4%). After 1-year follow-up, 14 patients were in class II (70%) and 5 were in class III (25%). Two sudden cardiac deaths occurred. A significant reduction in QRS length was found with BP (p=0.006). A significant statistical increase, from a mean of 19.13 ± 5.19% (at baseline) to 25.33 ± 5.90% (with BP) was observed in LVEF Premature ventricular contraction prevalence decreased from a mean of 10,670.00 ± 12,595.39 SD or to a mean of 3,007.00 ± 3,216.63 SD PVC/24 h with BP (p<0.05). Regarding the hospital admission rate over 1 year, we observed a significant reduction from 60. To 16 admissions with BP (p<0.05). CONCLUSION: Patients with LBBB and severe heart failure experienced, with BP, a significant NYHA class and LVEF improvement. A reduction in the hospital admission rate and VA prevalence also occurred.

  • biventricular pacing
  • Heart Failure
  • ventricular arrhythmias
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Creative Commons Attribution (CC BY) Creative Commons license
19/02/2002 DOI: 10.1590/S0066-782X2002000100010 Views 1

How to cite this article

EndNote RIS

Electronic Document Format (Vancouver)

Fº SSG, Barcellos CMB, Vasconcelos JTM, Arnez JGM, Couceiro KN, Campos L, Sbaraini E, et al. Ventricular resynchronization through biventricular cardiac pacing for the treatment of refractory heart failure in dilated cardiomyopathy. Arquivos Brasileiros de Cardiologia 2002;78(1):45-50.

Electronic Document Format (ABNT)

Fº, Silas S. Galvão; Barcellos, Cecília M. B.; Vasconcelos, J. Tarcísio M.; Arnez, Jaime G. M.; Couceiro, Kátia N.; Campos, Leudo; Sbaraini, Evandro; Lyra, Maurício G.; Souza, Fernando S. O.. Ventricular resynchronization through biventricular cardiac pacing for the treatment of refractory heart failure in dilated cardiomyopathy. Arquivos Brasileiros de Cardiologia, v. 78, n. 1, p. 45-50, Feb. 2002.

Electronic Document Format (APA)

Fº, S. S. G., Barcellos, C. M. B., Vasconcelos, J. T. M., Arnez, J. G. M., Couceiro, K. N., Campos, L., Sbaraini, E., Lyra, M. G., & Souza, F. S. O. (2002). Ventricular resynchronization through biventricular cardiac pacing for the treatment of refractory heart failure in dilated cardiomyopathy. Arquivos Brasileiros de Cardiologia, 78(1), 45-50.

Electronic Document Format (ISO)

Fº, Silas S. Galvão and Barcellos, Cecília M. B. and Vasconcelos, J. Tarcísio M. and Arnez, Jaime G. M. and Couceiro, Kátia N. and Campos, Leudo and Sbaraini, Evandro and Lyra, Maurício G. and Souza, Fernando S. O.. Ventricular resynchronization through biventricular cardiac pacing for the treatment of refractory heart failure in dilated cardiomyopathy. Arquivos Brasileiros de Cardiologia [online]. 2002, vol. 78, n. 1, [cited 2026-10-14], pp. 45-50. Available from: <https://journals.cardiol.br/en/article/ventricular-resynchronization-through-biventricular-cardiac-pacing-for-the-treatment-of-refractory-heart-failure-in-dilated-cardiomyopathy/>. ISSN 0066-782X

EndNote RIS

Electronic Document Format (Vancouver)

Martinelli Filho M, Pedrosa AAA, Costa R, Nishioka SAD, Siqueira SF, Tamaki WT, Sosa E, et al. Biventricular pacing improves clinical behavior and reduces prevalence of ventricular srrhythmia in patients with heart failure. Arquivos Brasileiros de Cardiologia 2002;78(1):110-3.

Electronic Document Format (ABNT)

Martinelli Filho, Martino; Pedrosa, Anísio A. A.; Costa, Roberto; Nishioka, Silvana A. D.; Siqueira, Sérgio F.; Tamaki, Wagner T.; Sosa, Eduardo. Biventricular pacing improves clinical behavior and reduces prevalence of ventricular srrhythmia in patients with heart failure. Arquivos Brasileiros de Cardiologia, v. 78, n. 1, p. 110-113, Feb. 2002.

Electronic Document Format (APA)

Martinelli Filho, M., Pedrosa, A. A. A., Costa, R., Nishioka, S. A. D., Siqueira, S. F., Tamaki, W. T., & Sosa, E. (2002). Biventricular pacing improves clinical behavior and reduces prevalence of ventricular srrhythmia in patients with heart failure. Arquivos Brasileiros de Cardiologia, 78(1), 110-113.

Electronic Document Format (ISO)

Martinelli Filho, Martino and Pedrosa, Anísio A. A. and Costa, Roberto and Nishioka, Silvana A. D. and Siqueira, Sérgio F. and Tamaki, Wagner T. and Sosa, Eduardo. Biventricular pacing improves clinical behavior and reduces prevalence of ventricular srrhythmia in patients with heart failure. Arquivos Brasileiros de Cardiologia [online]. 2002, vol. 78, n. 1, [cited 2026-10-14], pp. 110-113. Available from: <https://journals.cardiol.br/en/article/biventricular-pacing-improves-clinical-behavior-and-reduces-prevalence-of-ventricular-srrhythmia-in-patients-with-heart-failure/>. ISSN 0066-782X

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